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    Plag1 pleiomorphic adenoma gene 1 [ Mus musculus (house mouse) ]

    Gene ID: 56711, updated on 28-Jun-2021

    Summary

    Official Symbol
    Plag1provided by MGI
    Official Full Name
    pleiomorphic adenoma gene 1provided by MGI
    Primary source
    MGI:MGI:1891916
    See related
    Ensembl:ENSMUSG00000003282
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Expression
    Broad expression in limb E14.5 (RPKM 2.3), CNS E11.5 (RPKM 1.2) and 15 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Plag1 in Genome Data Viewer
    Location:
    4; 4 A1
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (3895209..3938429, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (3898769..3938430, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 4 NC_000070.5 (3828305..3865552, complement)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 32823 Neighboring gene predicted gene, 24125 Neighboring gene Moloney sarcoma oncogene Neighboring gene coiled-coil-helix-coiled-coil-helix domain containing 7 Neighboring gene ubiquitin protein ligase E3 component n-recognin 5 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1)  1 citation
    • Endonuclease-mediated (1) 

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Component Evidence Code Pubs
    located_in centrosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nuclear speck ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    zinc finger protein PLAG1
    Names
    C2H2 zinc finger protein PLAG1
    pleiomorphic adenoma gene 1 protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_019969.3NP_064353.2  zinc finger protein PLAG1

      See identical proteins and their annotated locations for NP_064353.2

      Status: VALIDATED

      Source sequence(s)
      AL807387, BC139283, CJ178210
      Consensus CDS
      CCDS17941.1
      UniProtKB/Swiss-Prot
      Q9QYE0
      Related
      ENSMUSP00000003369.4, ENSMUST00000003369.10
      Conserved Domains (3) summary
      COG5189
      Location:58139
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
      sd00017
      Location:3656
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:79103
      zf-H2C2_2; Zinc-finger double domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      3895209..3938429 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006538116.5XP_006538179.1  zinc finger protein PLAG1 isoform X1

      See identical proteins and their annotated locations for XP_006538179.1

      UniProtKB/Swiss-Prot
      Q9QYE0
      Conserved Domains (3) summary
      COG5189
      Location:58139
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
      sd00017
      Location:3656
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:79103
      zf-H2C2_2; Zinc-finger double domain
    2. XM_036164269.1XP_036020162.1  zinc finger protein PLAG1 isoform X1

      Conserved Domains (3) summary
      COG5189
      Location:58139
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
      sd00017
      Location:3656
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:79103
      zf-H2C2_2; Zinc-finger double domain
    3. XM_006538122.5XP_006538185.1  zinc finger protein PLAG1 isoform X3

      See identical proteins and their annotated locations for XP_006538185.1

      Conserved Domains (3) summary
      COG5236
      Location:39154
      COG5236; Uncharacterized conserved protein, contains RING Zn-finger [General function prediction only]
      sd00017
      Location:7090
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cd20908
      Location:1058
      SUF4-like; N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins
    4. XM_036164273.1XP_036020166.1  zinc finger protein PLAG1 isoform X3

      Conserved Domains (3) summary
      COG5236
      Location:39154
      COG5236; Uncharacterized conserved protein, contains RING Zn-finger [General function prediction only]
      sd00017
      Location:7090
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cd20908
      Location:1058
      SUF4-like; N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins
    5. XM_036164272.1XP_036020165.1  zinc finger protein PLAG1 isoform X3

      Conserved Domains (3) summary
      COG5236
      Location:39154
      COG5236; Uncharacterized conserved protein, contains RING Zn-finger [General function prediction only]
      sd00017
      Location:7090
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cd20908
      Location:1058
      SUF4-like; N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins
    6. XM_036164271.1XP_036020164.1  zinc finger protein PLAG1 isoform X2

      Conserved Domains (3) summary
      COG5236
      Location:41156
      COG5236; Uncharacterized conserved protein, contains RING Zn-finger [General function prediction only]
      sd00017
      Location:7292
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cd20908
      Location:1260
      SUF4-like; N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins
    7. XM_017320331.3XP_017175820.1  zinc finger protein PLAG1 isoform X1

      UniProtKB/Swiss-Prot
      Q9QYE0
      Conserved Domains (3) summary
      COG5189
      Location:58139
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
      sd00017
      Location:3656
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:79103
      zf-H2C2_2; Zinc-finger double domain
    8. XM_036164270.1XP_036020163.1  zinc finger protein PLAG1 isoform X1

      Conserved Domains (3) summary
      COG5189
      Location:58139
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
      sd00017
      Location:3656
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:79103
      zf-H2C2_2; Zinc-finger double domain
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