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    Dnajb12 DnaJ heat shock protein family (Hsp40) member B12 [ Mus musculus (house mouse) ]

    Gene ID: 56709, updated on 31-Jan-2019

    Summary

    Official Symbol
    Dnajb12provided by MGI
    Official Full Name
    DnaJ heat shock protein family (Hsp40) member B12provided by MGI
    Primary source
    MGI:MGI:1931881
    See related
    Ensembl:ENSMUSG00000020109
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Dj10; mDj10
    Expression
    Ubiquitous expression in kidney adult (RPKM 29.5), adrenal adult (RPKM 24.3) and 28 other tissues See more
    Orthologs

    Genomic context

    See Dnajb12 in Genome Data Viewer
    Location:
    10; 10 B4
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 10 NC_000076.6 (59879591..59898016)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 10 NC_000076.5 (59342339..59360764)

    Chromosome 10 - NC_000076.6Genomic Context describing neighboring genes Neighboring gene mitochondrial calcium uptake 1 Neighboring gene heterogeneous nuclear ribonucleoprotein A3 pseudogene Neighboring gene predicted gene 7413 Neighboring gene predicted gene, 46226 Neighboring gene predicted gene, 40673 Neighboring gene DNA-damage-inducible transcript 4

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    Pathways from BioSystems

    • Protein processing in endoplasmic reticulum, organism-specific biosystem (from KEGG)
      Protein processing in endoplasmic reticulum, organism-specific biosystemThe endoplasmic reticulum (ER) is a subcellular organelle where proteins are folded with the help of lumenal chaperones. Newly synthesized peptides enter the ER via the sec61 pore and are glycosylate...
    • Protein processing in endoplasmic reticulum, conserved biosystem (from KEGG)
      Protein processing in endoplasmic reticulum, conserved biosystemThe endoplasmic reticulum (ER) is a subcellular organelle where proteins are folded with the help of lumenal chaperones. Newly synthesized peptides enter the ER via the sec61 pore and are glycosylate...

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    Hsp70 protein binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Hsp70 protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    ERAD pathway ISO
    Inferred from Sequence Orthology
    more info
     
    cellular protein-containing complex assembly ISO
    Inferred from Sequence Orthology
    more info
     
    cellular response to misfolded protein IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cellular response to misfolded protein ISO
    Inferred from Sequence Orthology
    more info
     
    chaperone cofactor-dependent protein refolding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    chaperone cofactor-dependent protein refolding ISO
    Inferred from Sequence Orthology
    more info
     
    ubiquitin-dependent ERAD pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
     
    endoplasmic reticulum membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    integral component of endoplasmic reticulum membrane ISO
    Inferred from Sequence Orthology
    more info
     
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    dnaJ homolog subfamily B member 12
    Names
    DnaJ (Hsp40) homolog, subfamily B, member 12
    DnaJ homolog 10

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_019965.2NP_064349.2  dnaJ homolog subfamily B member 12

      See identical proteins and their annotated locations for NP_064349.2

      Status: PROVISIONAL

      Source sequence(s)
      BC034162
      Consensus CDS
      CCDS23867.1
      UniProtKB/Swiss-Prot
      Q9QYI4
      Related
      ENSMUSP00000122056.1, ENSMUST00000146590.7
      Conserved Domains (2) summary
      pfam00226
      Location:111172
      DnaJ; DnaJ domain
      pfam09320
      Location:269369
      DUF1977; Domain of unknown function (DUF1977)

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000076.6 Reference GRCm38.p4 C57BL/6J

      Range
      59879591..59898016
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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