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    NRIP3 nuclear receptor interacting protein 3 [ Homo sapiens (human) ]

    Gene ID: 56675, updated on 3-Apr-2024

    Summary

    Official Symbol
    NRIP3provided by HGNC
    Official Full Name
    nuclear receptor interacting protein 3provided by HGNC
    Primary source
    HGNC:HGNC:1167
    See related
    Ensembl:ENSG00000175352 MIM:613125; AllianceGenome:HGNC:1167
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    C11orf14; NY-SAR-105
    Summary
    Predicted to enable aspartic-type endopeptidase activity. Predicted to be involved in proteolysis. [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in testis (RPKM 15.1), brain (RPKM 14.4) and 4 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See NRIP3 in Genome Data Viewer
    Location:
    11p15.4
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (8980576..9004505, complement)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (9064768..9088208, complement)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (9002123..9025548, complement)

    Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene achaete-scute family bHLH transcription factor 3 Neighboring gene TMEM9 domain family member B Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3117 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3118 Neighboring gene TMEM9B antisense RNA 1 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:9000257-9001066 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:9024725-9025644 Neighboring gene NRIP3 divergent transcript Neighboring gene signal peptide, CUB domain and EGF like domain containing 2 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3119 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:9068585-9069086 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3120 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4398 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4399 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:9087649-9088150 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:9088151-9088650 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4400 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:9116861-9117362 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:9117363-9117862 Neighboring gene microRNA 5691 Neighboring gene keratin 8 pseudogene 41

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables aspartic-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    nuclear receptor-interacting protein 3
    Names
    sarcoma antigen NY-SAR-105

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_020645.3NP_065696.1  nuclear receptor-interacting protein 3

      See identical proteins and their annotated locations for NP_065696.1

      Status: VALIDATED

      Source sequence(s)
      AC026894, BC008835, DA249943
      Consensus CDS
      CCDS31422.1
      UniProtKB/Swiss-Prot
      Q86WD9, Q9NQ35
      UniProtKB/TrEMBL
      A0A8Q3WME3
      Related
      ENSP00000310205.3, ENST00000309166.8
      Conserved Domains (1) summary
      cd05480
      Location:110212
      NRIP_C; NRIP_C; putative nuclear receptor interacting protein

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

      Range
      8980576..9004505 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024448608.2XP_024304376.1  nuclear receptor-interacting protein 3 isoform X1

      Conserved Domains (1) summary
      cd05480
      Location:42144
      NRIP_C; putative nuclear receptor interacting protein
    2. XM_024448609.2XP_024304377.1  nuclear receptor-interacting protein 3 isoform X1

      Conserved Domains (1) summary
      cd05480
      Location:42144
      NRIP_C; putative nuclear receptor interacting protein
    3. XM_047427262.1XP_047283218.1  nuclear receptor-interacting protein 3 isoform X2

      UniProtKB/TrEMBL
      B7Z3Y4
      Related
      ENSP00000432451.1, ENST00000531090.5

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060935.1 Alternate T2T-CHM13v2.0

      Range
      9064768..9088208 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054369367.1XP_054225342.1  nuclear receptor-interacting protein 3 isoform X1

    2. XM_054369368.1XP_054225343.1  nuclear receptor-interacting protein 3 isoform X2

      UniProtKB/TrEMBL
      B7Z3Y4