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    Pex3 peroxisomal biogenesis factor 3 [ Mus musculus (house mouse) ]

    Gene ID: 56535, updated on 25-Jul-2018

    Summary

    Official Symbol
    Pex3provided by MGI
    Official Full Name
    peroxisomal biogenesis factor 3provided by MGI
    Primary source
    MGI:MGI:1929646
    See related
    Ensembl:ENSMUSG00000019809 Vega:OTTMUSG00000020905
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1700014F15Rik; 2810027F19Rik; 2900010N04Rik
    Expression
    Ubiquitous expression in testis adult (RPKM 24.6), bladder adult (RPKM 9.4) and 24 other tissues See more
    Orthologs

    Genomic context

    See Pex3 in Genome Data Viewer
    Location:
    10; 10 A2
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 10 NC_000076.6 (13523842..13553150, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 10 NC_000076.5 (13243648..13272948, complement)

    Chromosome 10 - NC_000076.6Genomic Context describing neighboring genes Neighboring gene phosphatase and actin regulator 2 Neighboring gene predicted gene, 46211 Neighboring gene fucosidase, alpha-L- 2, plasma Neighboring gene adenosine deaminase, tRNA-specific 2 Neighboring gene androgen-induced 1 Neighboring gene predicted gene, 32172 Neighboring gene predicted gene, 32105

    Genomic regions, transcripts, and products

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 

    Pathways from BioSystems

    General gene information

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    lipid binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein dimerization activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    peroxisome membrane biogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    peroxisome organization ISO
    Inferred from Sequence Orthology
    more info
     
    protein import into peroxisome membrane ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
     
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    integral component of peroxisomal membrane ISO
    Inferred from Sequence Orthology
    more info
     
    integral component of plasma membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    peroxisomal membrane ISO
    Inferred from Sequence Orthology
    more info
     
    peroxisome ISO
    Inferred from Sequence Orthology
    more info
     
    protein-containing complex ISO
    Inferred from Sequence Orthology
    more info
     
    protein-lipid complex ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    peroxisomal biogenesis factor 3
    Names
    peroxin-3
    peroxisomal assembly protein 3
    peroxisomal assembly protein PEX3

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001164195.1NP_001157667.1  peroxisomal biogenesis factor 3 isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an alternate exon in the 3' coding region, compared to variant 1. The resulting isoform (2) has a shorter and distinct C-terminus, compared to isoform 1.
      Source sequence(s)
      AC153979, AK005978, AV256241
      Consensus CDS
      CCDS48503.1
      UniProtKB/TrEMBL
      E9QA46
      Related
      ENSMUSP00000128512.1, ENSMUST00000170376.7
      Conserved Domains (1) summary
      pfam04882
      Location:11345
      Peroxin-3; Peroxin-3
    2. NM_001347361.1NP_001334290.1  peroxisomal biogenesis factor 3 isoform 3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) contains an alternate exon in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at a downstream start codon, compared to variant 1. The encoded isoform (3) has a shorter N-terminus and is shorter than isoform 1.
      Source sequence(s)
      AC153979, AK005315, AK013522
      Consensus CDS
      CCDS83681.1
      UniProtKB/TrEMBL
      D3Z6X4
    3. NM_019961.3NP_064345.1  peroxisomal biogenesis factor 3 isoform 1

      See identical proteins and their annotated locations for NP_064345.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
      Source sequence(s)
      AC153979, AK146934, CJ299039
      Consensus CDS
      CCDS23702.1
      UniProtKB/Swiss-Prot
      Q9QXY9
      UniProtKB/TrEMBL
      Q3UIG2
      Related
      ENSMUSP00000019945.8, OTTMUSP00000022888, ENSMUST00000019945.14, OTTMUST00000049414
      Conserved Domains (1) summary
      pfam04882
      Location:11361
      Peroxin-3; Peroxin-3

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000076.6 Reference GRCm38.p4 C57BL/6J

      Range
      13523842..13553150 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006512807.3XP_006512870.1  peroxisomal biogenesis factor 3 isoform X1

      Related
      ENSMUSP00000101178.1, OTTMUSP00000022899, ENSMUST00000105539.1, OTTMUST00000049426
      Conserved Domains (1) summary
      pfam04882
      Location:1295
      Peroxin-3; Peroxin-3
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