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    Pex3 peroxisomal biogenesis factor 3 [ Mus musculus (house mouse) ]

    Gene ID: 56535, updated on 23-Jun-2021

    Summary

    Official Symbol
    Pex3provided by MGI
    Official Full Name
    peroxisomal biogenesis factor 3provided by MGI
    Primary source
    MGI:MGI:1929646
    See related
    Ensembl:ENSMUSG00000019809
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1700014F15Rik; 2810027F19Rik; 2900010N04Rik
    Expression
    Ubiquitous expression in testis adult (RPKM 24.6), bladder adult (RPKM 9.4) and 24 other tissues See more
    Orthologs
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    Genomic context

    See Pex3 in Genome Data Viewer
    Location:
    10; 10 A2
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (13399586..13428886, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (13523842..13553142, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 10 NC_000076.5 (13243648..13272948, complement)

    Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene phosphatase and actin regulator 2 Neighboring gene predicted gene, 46211 Neighboring gene fucosidase, alpha-L- 2, plasma Neighboring gene adenosine deaminase, tRNA-specific 2 Neighboring gene uncharacterized LOC118567825 Neighboring gene androgen-induced 1 Neighboring gene predicted gene, 53613

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables lipid binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein-macromolecule adaptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in peroxisome membrane biogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in peroxisome organization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein import into peroxisome membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in protein import into peroxisome membrane ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
     
    located_in integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in integral component of peroxisomal membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in integral component of peroxisomal membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in integral component of plasma membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in peroxisomal membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in peroxisome ISO
    Inferred from Sequence Orthology
    more info
     
    part_of protein-containing complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of protein-lipid complex ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    peroxisomal biogenesis factor 3
    Names
    peroxin-3
    peroxisomal assembly protein 3
    peroxisomal assembly protein PEX3

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001164195.1NP_001157667.1  peroxisomal biogenesis factor 3 isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an alternate exon in the 3' coding region, compared to variant 1. The resulting isoform (2) has a shorter and distinct C-terminus, compared to isoform 1.
      Source sequence(s)
      AC153979, AK005978, AV256241
      Consensus CDS
      CCDS48503.1
      UniProtKB/TrEMBL
      E9QA46
      Related
      ENSMUSP00000128512.2, ENSMUST00000170376.8
      Conserved Domains (1) summary
      pfam04882
      Location:11345
      Peroxin-3; Peroxin-3
    2. NM_001347361.1NP_001334290.1  peroxisomal biogenesis factor 3 isoform 3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) contains an alternate exon in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at a downstream start codon, compared to variant 1. The encoded isoform (3) has a shorter N-terminus and is shorter than isoform 1.
      Source sequence(s)
      AC153979, AK005315, AK013522
      Consensus CDS
      CCDS83681.1
      UniProtKB/TrEMBL
      D3Z6X4
      Related
      ENSMUSP00000101178.2, ENSMUST00000105539.2
    3. NM_019961.3NP_064345.1  peroxisomal biogenesis factor 3 isoform 1

      See identical proteins and their annotated locations for NP_064345.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
      Source sequence(s)
      AC153979, AK146934, CJ299039
      Consensus CDS
      CCDS23702.1
      UniProtKB/Swiss-Prot
      Q9QXY9
      UniProtKB/TrEMBL
      Q3UIG2
      Related
      ENSMUSP00000019945.9, ENSMUST00000019945.15
      Conserved Domains (1) summary
      pfam04882
      Location:11361
      Peroxin-3; Peroxin-3

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000076.7 Reference GRCm39 C57BL/6J

      Range
      13399586..13428886 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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