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    Ruvbl1 RuvB-like protein 1 [ Mus musculus (house mouse) ]

    Gene ID: 56505, updated on 2-Oct-2018

    Summary

    Official Symbol
    Ruvbl1provided by MGI
    Official Full Name
    RuvB-like protein 1provided by MGI
    Primary source
    MGI:MGI:1928760
    See related
    Ensembl:ENSMUSG00000030079 Vega:OTTMUSG00000023968
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Tip49a; Pontin52; 2510009G06Rik
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 29.2), liver E14 (RPKM 28.2) and 28 other tissues See more
    Orthologs

    Genomic context

    See Ruvbl1 in Genome Data Viewer
    Location:
    6; 6 D1
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 6 NC_000072.6 (88465423..88497566)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 6 NC_000072.5 (88415417..88447560)

    Chromosome 6 - NC_000072.6Genomic Context describing neighboring genes Neighboring gene DnaJ heat shock protein family (Hsp40) member B8 Neighboring gene eukaryotic elongation factor, selenocysteine-tRNA-specific Neighboring gene predicted gene, 46965 Neighboring gene Sec61 alpha 1 subunit (S. cerevisiae) Neighboring gene kelch repeat and BTB (POZ) domain containing 12

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    ADP binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    ATP binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    ATP-dependent 3'-5' DNA helicase activity ISO
    Inferred from Sequence Orthology
    more info
     
    ATP-dependent 5'-3' DNA helicase activity IEA
    Inferred from Electronic Annotation
    more info
     
    ATP-dependent DNA helicase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    ATPase activity ISO
    Inferred from Sequence Orthology
    more info
     
    ATPase binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    DNA helicase activity ISO
    Inferred from Sequence Orthology
    more info
     
    TBP-class protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    TFIID-class transcription factor complex binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    helicase activity IEA
    Inferred from Electronic Annotation
    more info
     
    hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    transcription coactivator activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    DNA recombination IEA
    Inferred from Electronic Annotation
    more info
     
    DNA repair IEA
    Inferred from Electronic Annotation
    more info
     
    box C/D snoRNP assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    cell division IEA
    Inferred from Electronic Annotation
    more info
     
    cellular response to DNA damage stimulus IEA
    Inferred from Electronic Annotation
    more info
     
    chromatin organization IEA
    Inferred from Electronic Annotation
    more info
     
    chromatin remodeling IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    histone H2A acetylation ISO
    Inferred from Sequence Orthology
    more info
     
    histone H4 acetylation ISO
    Inferred from Sequence Orthology
    more info
     
    histone acetylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    positive regulation of canonical Wnt signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of plasminogen activation ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of fibroblast apoptotic process ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of growth IEA
    Inferred from Electronic Annotation
    more info
     
    regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    Ino80 complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Ino80 complex ISO
    Inferred from Sequence Orthology
    more info
     
    MLL1 complex ISO
    Inferred from Sequence Orthology
    more info
     
    NuA4 histone acetyltransferase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    NuA4 histone acetyltransferase complex ISO
    Inferred from Sequence Orthology
    more info
     
    R2TP complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    R2TP complex ISO
    Inferred from Sequence Orthology
    more info
     
    Swr1 complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Swr1 complex ISO
    Inferred from Sequence Orthology
    more info
     
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    nuclear matrix ISO
    Inferred from Sequence Orthology
    more info
     
    nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    protein-containing complex ISO
    Inferred from Sequence Orthology
    more info
     
    ribonucleoprotein complex IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    ruvB-like 1
    Names
    49 kDa TATA box-binding protein-interacting protein
    49 kDa TBP-interacting protein
    DNA helicase p50
    Pontin 52
    NP_062659.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_019685.3NP_062659.1  ruvB-like 1

      Status: VALIDATED

      Source sequence(s)
      AC153694, AF100694, AK132783
      Consensus CDS
      CCDS20336.1
      UniProtKB/Swiss-Prot
      P60122
      UniProtKB/TrEMBL
      Q3U1C2
      Related
      ENSMUSP00000032165.9, OTTMUSP00000028402, ENSMUST00000032165.15, OTTMUST00000058579
      Conserved Domains (1) summary
      pfam06068
      Location:14416
      TIP49; TIP49 C-terminus

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000072.6 Reference GRCm38.p4 C57BL/6J

      Range
      88465423..88497566
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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