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    Ruvbl1 RuvB-like protein 1 [ Mus musculus (house mouse) ]

    Gene ID: 56505, updated on 8-Jul-2021

    Summary

    Official Symbol
    Ruvbl1provided by MGI
    Official Full Name
    RuvB-like protein 1provided by MGI
    Primary source
    MGI:MGI:1928760
    See related
    Ensembl:ENSMUSG00000030079
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Pon; Tip; Tip49a; Pontin52; 2510009G06Rik
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 29.2), liver E14 (RPKM 28.2) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Ruvbl1 in Genome Data Viewer
    Location:
    6; 6 D1
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (88442391..88474548)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (88465409..88497566)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 6 NC_000072.5 (88415417..88447560)

    Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC118567399 Neighboring gene eukaryotic elongation factor, selenocysteine-tRNA-specific Neighboring gene predicted gene, 44264 Neighboring gene predicted gene, 46965 Neighboring gene Sec61 alpha 1 subunit (S. cerevisiae) Neighboring gene kelch repeat and BTB (POZ) domain containing 12

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables 3'-5' DNA helicase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables 5'-3' DNA helicase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables ADP binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables ATP binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables ATPase binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables DNA helicase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables DNA helicase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables TBP-class protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables TFIID-class transcription factor complex binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables helicase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables transcription coactivator activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within DNA recombination IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within DNA repair IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in box C/D snoRNP assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within cell division IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within cellular response to DNA damage stimulus IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within chromatin organization IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in chromatin remodeling IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in histone H2A acetylation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in histone H4 acetylation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in histone acetylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in positive regulation of canonical Wnt signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of plasminogen activation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of fibroblast apoptotic process ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within regulation of growth IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    part_of Ino80 complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of Ino80 complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of MLL1 complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of NuA4 histone acetyltransferase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of NuA4 histone acetyltransferase complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of R2TP complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of R2TP complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of Swr1 complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of Swr1 complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nuclear matrix ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    part_of protein-containing complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of ribonucleoprotein complex IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    ruvB-like 1
    Names
    49 kDa TATA box-binding protein-interacting protein
    49 kDa TBP-interacting protein
    DNA helicase p50
    Pontin 52
    NP_062659.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_019685.3NP_062659.1  ruvB-like 1

      See identical proteins and their annotated locations for NP_062659.1

      Status: VALIDATED

      Source sequence(s)
      AC153694, AF100694, AK132783
      Consensus CDS
      CCDS20336.1
      UniProtKB/Swiss-Prot
      P60122
      UniProtKB/TrEMBL
      Q3U1C2
      Related
      ENSMUSP00000032165.10, ENSMUST00000032165.16
      Conserved Domains (1) summary
      COG1224
      Location:2455
      TIP49; DNA helicase TIP49, TBP-interacting protein [Transcription]

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000072.7 Reference GRCm39 C57BL/6J

      Range
      88442391..88474548
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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