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    RPRM reprimo, TP53 dependent G2 arrest mediator homolog [ Homo sapiens (human) ]

    Gene ID: 56475, updated on 17-Sep-2024

    Summary

    Official Symbol
    RPRMprovided by HGNC
    Official Full Name
    reprimo, TP53 dependent G2 arrest mediator homologprovided by HGNC
    Primary source
    HGNC:HGNC:24201
    See related
    Ensembl:ENSG00000177519 MIM:612171; AllianceGenome:HGNC:24201
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    REPRIMO
    Summary
    Predicted to be involved in regulation of mitotic cell cycle. Predicted to act upstream of or within regulation of cell cycle. Predicted to be integral component of membrane. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    NEW
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    Genomic context

    See RPRM in Genome Data Viewer
    Location:
    2q23.3
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 2 NC_000002.12 (153477338..153478762, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 2 NC_060926.1 (153929892..153931316, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (154333852..154335276, complement)

    Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene polypeptide N-acetylgalactosaminyltransferase 13 Neighboring gene small nucleolar RNA SNORD56 Neighboring gene NANOG hESC enhancer GRCh37_chr2:154316044-154316575 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr2:154333443-154333946 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr2:154333947-154334450 Neighboring gene H3K27ac hESC enhancer GRCh37_chr2:154334451-154334954 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 12014 Neighboring gene NANOG hESC enhancer GRCh37_chr2:154352121-154352622 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:154354490-154355011 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:154355012-154355532 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:154355799-154356300 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:154365323-154365825 Neighboring gene tubulin alpha pseudogene 13 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr2:154391191-154391794 Neighboring gene NANOG hESC enhancer GRCh37_chr2:154400187-154400737 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr2:154449049-154450248 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:154575691-154576266 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:154576267-154576842 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:154621524-154622079 Neighboring gene DnaJ heat shock protein family (Hsp40) member A1 pseudogene 2 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr2:154747006-154747567 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:154769701-154770201 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr2:155097618-155098817 Neighboring gene PHB1 pseudogene 4

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • FLJ90327

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in regulation of cell cycle TAS
    Traceable Author Statement
    more info
    PubMed 
    involved_in regulation of mitotic cell cycle IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    protein reprimo
    Names
    candidate mediator of the p53 dependent G2 arrest
    reprimo, TP53 dependant G2 arrest mediator candidate
    reprimo, TP53 dependent G2 arrest mediator candidate

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_019845.3NP_062819.1  protein reprimo

      See identical proteins and their annotated locations for NP_062819.1

      Status: VALIDATED

      Source sequence(s)
      AA452090, BC002908
      Consensus CDS
      CCDS2198.1
      UniProtKB/Swiss-Prot
      B2R4V1, Q9NS64
      Related
      ENSP00000314946.3, ENST00000325926.4

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000002.12 Reference GRCh38.p14 Primary Assembly

      Range
      153477338..153478762 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060926.1 Alternate T2T-CHM13v2.0

      Range
      153929892..153931316 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)