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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_001333.2
- Range
-
624987..628610
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
-
NG_008322.2 RefSeqGene
- Range
-
5028..8618
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
NM_001303414.2 → NP_001290343.1 trypsin-2 isoform 1 preproprotein
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (1).
- Source sequence(s)
-
AC245427, BC005814, BC030260, CA867206, DQ846873
- Consensus CDS
-
CCDS83235.1
- UniProtKB/TrEMBL
- A6XMV8, A6XMV9, Q3SY20
- Related
- ENSP00000488437.1, ENST00000633969.1
- Conserved Domains (2) summary
-
- smart00020
Location:23 → 253
- Tryp_SPc; Trypsin-like serine protease
- cd00190
Location:24 → 256
- Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
-
NM_002770.4 → NP_002761.1 trypsin-2 isoform 2 preproprotein
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) lacks an in-frame exon compared to variant 1. The encoded isoform (2) is shorter than isoform 1.
- Source sequence(s)
-
AC245427, BC005814, BC030260, CA867206
- Consensus CDS
-
CCDS83236.1
- UniProtKB/Swiss-Prot
-
P07478
- UniProtKB/TrEMBL
- Q3SY20, Q5NV56
- Related
- ENSP00000488338.1, ENST00000539842.6
- Conserved Domains (2) summary
-
- smart00020
Location:23 → 239
- Tryp_SPc; Trypsin-like serine protease
- cd00190
Location:24 → 242
- Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
RNA
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NR_130149.2 RNA Sequence
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) lacks an internal exon and uses an alternate splice acceptor site at an internal exon compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
- Source sequence(s)
-
AC245427, BC005814, BC030260, CA867206, CA951033
- Related
-
ENST00000618750.2
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000007.14 Reference GRCh38.p14 Primary Assembly
- Range
-
142770970..142774560
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
Reference GRCh38.p14 ALT_REF_LOCI_1
Genomic
-
NT_187562.1 Reference GRCh38.p14 ALT_REF_LOCI_1
- Range
-
793943..797533
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
Alternate T2T-CHM13v2.0
Genomic
-
NC_060931.1 Alternate T2T-CHM13v2.0
- Range
-
144116104..144130278
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054358659.1 → XP_054214634.1 trypsin-2 isoform X1
- UniProtKB/TrEMBL
- A0A0J9YYC8, Q3SY20