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    Adrm1 adhesion regulating molecule 1 [ Mus musculus (house mouse) ]

    Gene ID: 56436, updated on 31-Jan-2019

    Summary

    Official Symbol
    Adrm1provided by MGI
    Official Full Name
    adhesion regulating molecule 1provided by MGI
    Primary source
    MGI:MGI:1929289
    See related
    Ensembl:ENSMUSG00000039041
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Arm1; ARM-1; Gp110; Rpn13; AA408205; AU043535; 1110063P18Rik; 2510006J17Rik
    Expression
    Ubiquitous expression in adrenal adult (RPKM 108.3), duodenum adult (RPKM 65.5) and 28 other tissues See more
    Orthologs

    Genomic context

    See Adrm1 in Genome Data Viewer
    Location:
    2; 2 H4
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 2 NC_000068.7 (180171490..180176284)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (179906293..179910988)

    Chromosome 2 - NC_000068.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 46782 Neighboring gene oxysterol binding protein-like 2 Neighboring gene predicted gene, 29886 Neighboring gene microRNA 7005 Neighboring gene laminin, alpha 5 Neighboring gene microRNA 3091 Neighboring gene ribosomal protein S21

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    endopeptidase activator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    endopeptidase activator activity ISO
    Inferred from Sequence Orthology
    more info
     
    protease binding ISO
    Inferred from Sequence Orthology
    more info
     
    proteasome binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    proteasome binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    ubiquitin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    Sertoli cell development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    adipose tissue development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    follicle-stimulating hormone signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    oogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    ovarian follicle development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of growth hormone receptor signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    proteasome assembly ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of T cell differentiation in thymus IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    seminiferous tubule development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    spermatid development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    thymus development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    transcription elongation from RNA polymerase II promoter ISO
    Inferred from Sequence Orthology
    more info
     
    ubiquitin-dependent protein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    proteasome complex ISO
    Inferred from Sequence Orthology
    more info
     
    proteasome regulatory particle, lid subcomplex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    proteasomal ubiquitin receptor ADRM1
    Names
    110 kDa cell membrane glycoprotein
    glycoprotein 110
    rpn13 homolog

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_019822.3NP_062796.2  proteasomal ubiquitin receptor ADRM1

      See identical proteins and their annotated locations for NP_062796.2

      Status: PROVISIONAL

      Source sequence(s)
      AL663027
      Consensus CDS
      CCDS17171.1
      UniProtKB/Swiss-Prot
      Q9JKV1
      Related
      ENSMUSP00000050076.4, ENSMUST00000061437.4
      Conserved Domains (2) summary
      cd13314
      Location:24128
      PH_Rpn13; Pleckstrin homology-like domain of Regulatory Particle Non-ATPase 13
      pfam16550
      Location:274381
      RPN13_C; UCH-binding domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000068.7 Reference GRCm38.p4 C57BL/6J

      Range
      180171490..180176284
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006500680.3XP_006500743.1  proteasomal ubiquitin receptor ADRM1 isoform X1

      UniProtKB/TrEMBL
      A0A1S6GWG3
      Conserved Domains (2) summary
      cd13314
      Location:87191
      PH_Rpn13; Pleckstrin homology-like domain of Regulatory Particle Non-ATPase 13
      pfam16550
      Location:337444
      RPN13_C; UCH-binding domain
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