Format

Send to:

Choose Destination
    • Showing Current items.

    Nudt3 nudix (nucleotide diphosphate linked moiety X)-type motif 3 [ Mus musculus (house mouse) ]

    Gene ID: 56409, updated on 12-Aug-2018

    Summary

    Official Symbol
    Nudt3provided by MGI
    Official Full Name
    nudix (nucleotide diphosphate linked moiety X)-type motif 3provided by MGI
    Primary source
    MGI:MGI:1928484
    See related
    Ensembl:ENSMUSG00000024213 Vega:OTTMUSG00000018655
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Dipp; Dipp1; AA960325; 1110011B09Rik
    Expression
    Ubiquitous expression in CNS E18 (RPKM 71.3), adrenal adult (RPKM 66.7) and 28 other tissues See more
    Orthologs

    Genomic context

    See Nudt3 in Genome Data Viewer
    Location:
    17; 17 A3.3
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 17 NC_000083.6 (27579382..27623452, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 17 NC_000083.5 (27716336..27760397, complement)

    Chromosome 17 - NC_000083.6Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA C130040N14 gene Neighboring gene high mobility group AT-hook 1 Neighboring gene expressed sequence AI413582 Neighboring gene ribosomal protein S10 Neighboring gene predicted gene 15420 Neighboring gene protein kinase C and casein kinase substrate in neurons 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 

    Pathways from BioSystems

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    bis(5'-adenosyl)-hexaphosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    bis(5'-adenosyl)-pentaphosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    diphosphoinositol-polyphosphate diphosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    diphosphoinositol-polyphosphate diphosphatase activity ISO
    Inferred from Sequence Orthology
    more info
     
    endopolyphosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    m7G(5')pppN diphosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    magnesium ion binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    adenosine 5'-(hexahydrogen pentaphosphate) catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    diadenosine hexaphosphate catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    diadenosine pentaphosphate catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    diphosphoinositol polyphosphate catabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    diphosphoinositol polyphosphate metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    diphosphoinositol polyphosphate phosphohydrolase 1
    Names
    DIPP-1
    diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 1
    NP_001277975.1
    NP_062811.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001291046.1NP_001277975.1  diphosphoinositol polyphosphate phosphohydrolase 1 isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an alternate 5' terminal exon compared to variant 1. The resulting protein (isoform 1) is shorter and has a distinct N-terminus compared to isoform 1.
      Source sequence(s)
      AC127341, AC131800, BU919402
      Consensus CDS
      CCDS70776.1
      UniProtKB/TrEMBL
      B2KF67
      Related
      ENSMUSP00000110536.1, OTTMUSP00000028938, ENSMUST00000114886.7, OTTMUST00000050575
      Conserved Domains (1) summary
      cd04666
      Location:4105
      Nudix_Hydrolase_9; Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly ...
    2. NM_019837.2NP_062811.1  diphosphoinositol polyphosphate phosphohydrolase 1 isoform 1

      See identical proteins and their annotated locations for NP_062811.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the longer protein (isoform 1).
      Source sequence(s)
      AC127341, AC131800
      Consensus CDS
      CCDS28566.1
      UniProtKB/Swiss-Prot
      Q9JI46
      Related
      ENSMUSP00000025050.5, OTTMUSP00000020186, ENSMUST00000025050.12, OTTMUST00000044911
      Conserved Domains (1) summary
      cd04666
      Location:19134
      Nudix_Hydrolase_9; Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly ...

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000083.6 Reference GRCm38.p4 C57BL/6J

      Range
      27579382..27623452 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCm38.p4 NOD/ShiLtJ

    Genomic

    1. NT_187005.1 Reference GRCm38.p4 NOD/ShiLtJ

      Range
      269320..313395 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Support Center