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    Arpc3 actin related protein 2/3 complex, subunit 3 [ Mus musculus (house mouse) ]

    Gene ID: 56378, updated on 23-Jun-2021

    Summary

    Official Symbol
    Arpc3provided by MGI
    Official Full Name
    actin related protein 2/3 complex, subunit 3provided by MGI
    Primary source
    MGI:MGI:1928375
    See related
    Ensembl:ENSMUSG00000029465
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    p21; p21-Ar; p21Arc; p21-ARC; 1110006A04Rik
    Expression
    Ubiquitous expression in placenta adult (RPKM 128.4), large intestine adult (RPKM 106.1) and 28 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Arpc3 in Genome Data Viewer
    Location:
    5; 5 F
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (122529941..122544244)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (122391878..122406181)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 5 NC_000071.5 (122841937..122856187)

    Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene VPS29 retromer complex component Neighboring gene family with sequence similarity 216, member A Neighboring gene GPN-loop GTPase 3 Neighboring gene predicted gene, 32853 Neighboring gene anaphase promoting complex subunit 7 Neighboring gene ATPase, Ca++ transporting, cardiac muscle, slow twitch 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • 1110006A04Rik

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables actin binding IEA
    Inferred from Electronic Annotation
    more info
     
    contributes_to actin filament binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    contributes_to actin filament binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables structural constituent of cytoskeleton ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in Arp2/3 complex-mediated actin nucleation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in Arp2/3 complex-mediated actin nucleation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of actin filament polymerization IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    part_of Arp2/3 protein complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of Arp2/3 protein complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of Arp2/3 protein complex TAS
    Traceable Author Statement
    more info
    PubMed 
    located_in cell leading edge ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cell projection IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    part_of filamentous actin ISO
    Inferred from Sequence Orthology
    more info
     
    located_in growth cone leading edge ISO
    Inferred from Sequence Orthology
    more info
     
    located_in lamellipodium IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in lamellipodium ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    actin-related protein 2/3 complex subunit 3
    Names
    Arp2/3 complex subunit p21-Arc
    arp2/3 complex 21 kDa subunit

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_019824.4NP_062798.1  actin-related protein 2/3 complex subunit 3

      See identical proteins and their annotated locations for NP_062798.1

      Status: VALIDATED

      Source sequence(s)
      AK003485, BY790451, CJ220494
      Consensus CDS
      CCDS19648.1
      UniProtKB/Swiss-Prot
      Q9JM76
      Related
      ENSMUSP00000099584.5, ENSMUST00000102525.11
      Conserved Domains (1) summary
      pfam04062
      Location:1173
      P21-Arc; ARP2/3 complex ARPC3 (21 kDa) subunit

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000071.7 Reference GRCm39 C57BL/6J

      Range
      122529941..122544244
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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