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    Pdlim5 PDZ and LIM domain 5 [ Mus musculus (house mouse) ]

    Gene ID: 56376, updated on 23-Jun-2021

    Summary

    Official Symbol
    Pdlim5provided by MGI
    Official Full Name
    PDZ and LIM domain 5provided by MGI
    Primary source
    MGI:MGI:1927489
    See related
    Ensembl:ENSMUSG00000028273
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    En; Enh; LIM; Enh1; Enh2; Enh3; C87059; AI987914; 1110001A05Rik
    Expression
    Broad expression in heart adult (RPKM 41.4), bladder adult (RPKM 16.5) and 27 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Pdlim5 in Genome Data Viewer
    Location:
    3; 3 H1
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (141945346..142101480, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (142239585..142395719, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 3 NC_000069.5 (141903568..142058630, complement)

    Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene unc-5 netrin receptor C Neighboring gene bone morphogenetic protein receptor, type 1B Neighboring gene GABA(A) receptor-associated protein-like 2 pseudogene 3 Neighboring gene VISTA enhancer mm1018 Neighboring gene predicted gene, 33189

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables actin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables actin binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables actinin binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables muscle alpha-actinin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables protein N-terminus binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein kinase C binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in actin cytoskeleton organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in cell growth involved in cardiac muscle cell development ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in heart development IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in muscle structure development IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in regulation of dendritic spine morphogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of synapse assembly ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    is_active_in Z disc IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in Z disc IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in actin cytoskeleton ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in adherens junction IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in cell junction IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cell projection IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    part_of filamentous actin IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in postsynaptic density ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in stress fiber IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in synapse IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    PDZ and LIM domain protein 5
    Names
    enigma homolog
    enigma-like PDZ and LIM domains protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001190852.1NP_001177781.1  PDZ and LIM domain protein 5 isoform ENH1e

      See identical proteins and their annotated locations for NP_001177781.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) represents the longest transcript and it encodes the longest protein (isoform ENH1e).
      Source sequence(s)
      AC139128, AC158581, AK147999, BY227455, DV551664
      Consensus CDS
      CCDS80038.1
      UniProtKB/Swiss-Prot
      Q8CI51
      UniProtKB/TrEMBL
      D9J302
      Related
      ENSMUSP00000142737.2, ENSMUST00000195975.5
      Conserved Domains (5) summary
      cd09453
      Location:438489
      LIM1_ENH; The first LIM domain of the Enigma Homolog (ENH) family
      cd00992
      Location:1082
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam15229
      Location:303413
      POM121; POM121 family
      pfam15936
      Location:105185
      DUF4749; Domain of unknown function (DUF4749)
      cl02475
      Location:556610
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
    2. NM_001190853.1NP_001177782.1  PDZ and LIM domain protein 5 isoform ENH4

      See identical proteins and their annotated locations for NP_001177782.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (5) has multiple differences, compared to variant 4. The resulting protein (isoform ENH4) has a shorter and distinct C-terminus when compared to isoform ENH1e.
      Source sequence(s)
      AC139128, AC158581, AK009464
      Consensus CDS
      CCDS57258.1
      UniProtKB/TrEMBL
      Q9CRA2
      Related
      ENSMUSP00000087595.6, ENSMUST00000090134.12
      Conserved Domains (2) summary
      cd00992
      Location:1082
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam15936
      Location:100171
      DUF4749; Domain of unknown function (DUF4749)
    3. NM_001190854.1NP_001177783.1  PDZ and LIM domain protein 5 isoform ENH1b

      See identical proteins and their annotated locations for NP_001177783.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (6) lacks three alternate exons, compared to variant 4. The resulting protein (isoform ENH1b) is shorter, compared to isoform ENH1e.
      Source sequence(s)
      AC139128, AC158581, AK147999, BY227455, DV551664
      Consensus CDS
      CCDS80035.1
      UniProtKB/Swiss-Prot
      Q8CI51
      UniProtKB/TrEMBL
      D9J2Z9
      Related
      ENSMUSP00000142899.2, ENSMUST00000198381.5
      Conserved Domains (5) summary
      PHA03381
      Location:136323
      PHA03381; tegument protein VP22; Provisional
      cd09453
      Location:306357
      LIM1_ENH; The first LIM domain of the Enigma Homolog (ENH) family
      cd00992
      Location:1082
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam15936
      Location:105185
      DUF4749; Domain of unknown function (DUF4749)
      cl02475
      Location:424478
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
    4. NM_001190855.1NP_001177784.1  PDZ and LIM domain protein 5 isoform ENH1c

      See identical proteins and their annotated locations for NP_001177784.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (7) lacks two alternate exons, compared to variant 4. The resulting protein (isoform ENH1c) is shorter when it is compared to isoform ENH1e.
      Source sequence(s)
      AC139128, AC158581, AK147999, BY227455, DV551664
      Consensus CDS
      CCDS80036.1
      UniProtKB/Swiss-Prot
      Q8CI51
      UniProtKB/TrEMBL
      D9J300
      Related
      ENSMUSP00000143343.2, ENSMUST00000200043.5
      Conserved Domains (5) summary
      cd09453
      Location:350401
      LIM1_ENH; The first LIM domain of the Enigma Homolog (ENH) family
      cd00992
      Location:1082
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam15229
      Location:215325
      POM121; POM121 family
      pfam15936
      Location:105185
      DUF4749; Domain of unknown function (DUF4749)
      cl02475
      Location:468522
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
    5. NM_001190856.1NP_001177785.1  PDZ and LIM domain protein 5 isoform ENH1d

      See identical proteins and their annotated locations for NP_001177785.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (8) lacks an alternate exon, compared to variant 4. The resulting protein (isoform ENH1d) is shorter when it is compared to isoform ENH1e.
      Source sequence(s)
      AC139128, AC158581, AK147999, BY227455, DV551664
      Consensus CDS
      CCDS80037.1
      UniProtKB/Swiss-Prot
      Q8CI51
      UniProtKB/TrEMBL
      D9J301
      Related
      ENSMUSP00000142460.2, ENSMUST00000196220.5
      Conserved Domains (5) summary
      cd09453
      Location:398449
      LIM1_ENH; The first LIM domain of the Enigma Homolog (ENH) family
      cd00992
      Location:1082
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam15229
      Location:263373
      POM121; POM121 family
      pfam15936
      Location:105185
      DUF4749; Domain of unknown function (DUF4749)
      cl02475
      Location:516570
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
    6. NM_001190857.1NP_001177786.1  PDZ and LIM domain protein 5 isoform ENH3a

      See identical proteins and their annotated locations for NP_001177786.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (9) has multiple differences in the 3' end, compared to variant 4. The resulting protein (isoform ENH3a) has a shorter and distinct C-terminus when compared to isoform ENH1e.
      Source sequence(s)
      AA061806, AC139128, BY227455, CA534475, CB597177
      Consensus CDS
      CCDS80039.1
      UniProtKB/TrEMBL
      D9J303
      Related
      ENSMUSP00000132647.4, ENSMUST00000168967.9
      Conserved Domains (2) summary
      cd00992
      Location:1082
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam15936
      Location:105201
      DUF4749; Domain of unknown function (DUF4749)
    7. NM_019808.3NP_062782.2  PDZ and LIM domain protein 5 isoform ENH1

      See identical proteins and their annotated locations for NP_062782.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) uses a different splice site and lacks alternate segments, compared to variant 4. The resulting protein (isoform ENH1) is shorter when it is compared to isoform ENH1e. This isoform has also been called ENH1/1a.
      Source sequence(s)
      AC139128, AC158581, AK147999, BY227455, DV551664
      Consensus CDS
      CCDS17875.1
      UniProtKB/Swiss-Prot
      Q8CI51
      Related
      ENSMUSP00000029941.10, ENSMUST00000029941.16
      Conserved Domains (5) summary
      cd09453
      Location:415466
      LIM1_ENH; The first LIM domain of the Enigma Homolog (ENH) family
      cd00992
      Location:1082
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam15741
      Location:75388
      LRIF1; Ligand-dependent nuclear receptor-interacting factor 1
      pfam15936
      Location:214294
      DUF4749; Domain of unknown function (DUF4749)
      cl02475
      Location:533587
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
    8. NM_019809.3NP_062783.2  PDZ and LIM domain protein 5 isoform ENH2

      See identical proteins and their annotated locations for NP_062783.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses a different splice site and has multiple differences in the 3' end, compared to variant 4. The resulting protein (isoform ENH2) is shorter and has a distinct C-terminus when it is compared to isoform ENH1e.
      Source sequence(s)
      AC139128, AC158581, AI391027, AK009464, BY227455, BY741234
      Consensus CDS
      CCDS17876.1
      UniProtKB/TrEMBL
      Q9CRA2
      Related
      ENSMUSP00000143098.2, ENSMUST00000196908.5
      Conserved Domains (2) summary
      cd00992
      Location:1082
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam15936
      Location:214294
      DUF4749; Domain of unknown function (DUF4749)
    9. NM_022554.3NP_072048.2  PDZ and LIM domain protein 5 isoform ENH3b

      See identical proteins and their annotated locations for NP_072048.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) has multiple differences, compared to variant 4. The resulting protein (isoform ENH3b) has a shorter and distinct C-terminus when it is compared to isoform ENH1e. The encoded isoform was previously known as ENH3b.
      Source sequence(s)
      AA512794, AC139128, BY227455, CA534475
      Consensus CDS
      CCDS38656.1
      UniProtKB/TrEMBL
      E9Q8P5
      Related
      ENSMUSP00000128752.3, ENSMUST00000170361.9
      Conserved Domains (2) summary
      cd00992
      Location:1082
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam15936
      Location:105206
      DUF4749; Domain of unknown function (DUF4749)

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000069.7 Reference GRCm39 C57BL/6J

      Range
      141945346..142101480 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017319659.2XP_017175148.1  PDZ and LIM domain protein 5 isoform X11

      Conserved Domains (4) summary
      cd09453
      Location:424475
      LIM1_ENH; The first LIM domain of the Enigma Homolog (ENH) family
      cd00992
      Location:1082
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cl02475
      Location:542596
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
      pfam15936
      Location:115181
      DUF4749; Domain of unknown function (DUF4749)
    2. XM_036163173.1XP_036019066.1  PDZ and LIM domain protein 5 isoform X14

      Conserved Domains (4) summary
      cd09453
      Location:354405
      LIM1_ENH; The first LIM domain of the Enigma Homolog (ENH) family
      cd00992
      Location:1082
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam15936
      Location:105195
      DUF4749; Domain of unknown function (DUF4749)
      cl02475
      Location:472526
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
    3. XM_006501748.2XP_006501811.1  PDZ and LIM domain protein 5 isoform X15

      Conserved Domains (5) summary
      PHA03381
      Location:132329
      PHA03381; tegument protein VP22; Provisional
      cd09453
      Location:312363
      LIM1_ENH; The first LIM domain of the Enigma Homolog (ENH) family
      cd00992
      Location:1082
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cl02475
      Location:430484
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
      pfam15936
      Location:105201
      DUF4749; Domain of unknown function (DUF4749)
    4. XM_036163172.1XP_036019065.1  PDZ and LIM domain protein 5 isoform X13

      Conserved Domains (4) summary
      cd09453
      Location:360411
      LIM1_ENH; The first LIM domain of the Enigma Homolog (ENH) family
      cd00992
      Location:1082
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam15936
      Location:105201
      DUF4749; Domain of unknown function (DUF4749)
      cl02475
      Location:478532
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
    5. XM_006501745.2XP_006501808.1  PDZ and LIM domain protein 5 isoform X9

      Conserved Domains (4) summary
      cd09453
      Location:444495
      LIM1_ENH; The first LIM domain of the Enigma Homolog (ENH) family
      cd00992
      Location:1082
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cl02475
      Location:562616
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
      pfam15936
      Location:105201
      DUF4749; Domain of unknown function (DUF4749)
    6. XM_006501744.2XP_006501807.1  PDZ and LIM domain protein 5 isoform X8

      Conserved Domains (5) summary
      cd09453
      Location:449500
      LIM1_ENH; The first LIM domain of the Enigma Homolog (ENH) family
      cd09457
      Location:508559
      LIM2_ENH; The second LIM domain of the Enigma Homolog (ENH) family
      cd00992
      Location:1082
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cl02475
      Location:567621
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
      pfam15936
      Location:105206
      DUF4749; Domain of unknown function (DUF4749)
    7. XM_036163170.1XP_036019063.1  PDZ and LIM domain protein 5 isoform X6

      Conserved Domains (5) summary
      cd09453
      Location:507558
      LIM1_ENH; The first LIM domain of the Enigma Homolog (ENH) family
      cd09457
      Location:566617
      LIM2_ENH; The second LIM domain of the Enigma Homolog (ENH) family
      cd09459
      Location:625679
      LIM3_ENH; The third LIM domain of the Enigma Homolog (ENH) family
      cd00992
      Location:1082
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam15936
      Location:214304
      DUF4749; Domain of unknown function (DUF4749)
    8. XM_006501740.2XP_006501803.1  PDZ and LIM domain protein 5 isoform X3

      Conserved Domains (5) summary
      cd09453
      Location:547598
      LIM1_ENH; The first LIM domain of the Enigma Homolog (ENH) family
      cd09457
      Location:606657
      LIM2_ENH; The second LIM domain of the Enigma Homolog (ENH) family
      cd09459
      Location:665719
      LIM3_ENH; The third LIM domain of the Enigma Homolog (ENH) family
      cd00992
      Location:1082
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam15936
      Location:214304
      DUF4749; Domain of unknown function (DUF4749)
    9. XM_036163171.1XP_036019064.1  PDZ and LIM domain protein 5 isoform X12

      Conserved Domains (5) summary
      cd09453
      Location:421472
      LIM1_ENH; The first LIM domain of the Enigma Homolog (ENH) family
      cd09459
      Location:539593
      LIM3_ENH; The third LIM domain of the Enigma Homolog (ENH) family
      PHA03307
      Location:82403
      PHA03307; transcriptional regulator ICP4; Provisional
      cd00992
      Location:1082
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cl02475
      Location:480531
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
    10. XM_006501739.2XP_006501802.1  PDZ and LIM domain protein 5 isoform X2

      Conserved Domains (5) summary
      cd09453
      Location:553604
      LIM1_ENH; The first LIM domain of the Enigma Homolog (ENH) family
      cd09457
      Location:612663
      LIM2_ENH; The second LIM domain of the Enigma Homolog (ENH) family
      cd09459
      Location:671725
      LIM3_ENH; The third LIM domain of the Enigma Homolog (ENH) family
      cd00992
      Location:1082
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam15936
      Location:214310
      DUF4749; Domain of unknown function (DUF4749)
    11. XM_006501746.2XP_006501809.1  PDZ and LIM domain protein 5 isoform X10

      Conserved Domains (5) summary
      cd09453
      Location:426477
      LIM1_ENH; The first LIM domain of the Enigma Homolog (ENH) family
      cd09459
      Location:544598
      LIM3_ENH; The third LIM domain of the Enigma Homolog (ENH) family
      PHA03307
      Location:82408
      PHA03307; transcriptional regulator ICP4; Provisional
      cd00992
      Location:1082
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cl02475
      Location:485536
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
    12. XM_006501743.2XP_006501806.1  PDZ and LIM domain protein 5 isoform X7

      Conserved Domains (6) summary
      cd09453
      Location:474525
      LIM1_ENH; The first LIM domain of the Enigma Homolog (ENH) family
      cd09457
      Location:533584
      LIM2_ENH; The second LIM domain of the Enigma Homolog (ENH) family
      cd09459
      Location:592646
      LIM3_ENH; The third LIM domain of the Enigma Homolog (ENH) family
      PRK12323
      Location:79274
      PRK12323; DNA polymerase III subunit gamma/tau
      cd00992
      Location:1082
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam15936
      Location:214315
      DUF4749; Domain of unknown function (DUF4749)
    13. XM_006501741.2XP_006501804.1  PDZ and LIM domain protein 5 isoform X4

      Conserved Domains (6) summary
      cd09453
      Location:518569
      LIM1_ENH; The first LIM domain of the Enigma Homolog (ENH) family
      cd09457
      Location:577628
      LIM2_ENH; The second LIM domain of the Enigma Homolog (ENH) family
      cd09459
      Location:636690
      LIM3_ENH; The third LIM domain of the Enigma Homolog (ENH) family
      PHA03307
      Location:150537
      PHA03307; transcriptional regulator ICP4; Provisional
      cd00992
      Location:1082
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam15936
      Location:214315
      DUF4749; Domain of unknown function (DUF4749)
    14. XM_006501742.2XP_006501805.1  PDZ and LIM domain protein 5 isoform X5

      Conserved Domains (6) summary
      cd09453
      Location:514565
      LIM1_ENH; The first LIM domain of the Enigma Homolog (ENH) family
      cd09457
      Location:573624
      LIM2_ENH; The second LIM domain of the Enigma Homolog (ENH) family
      cd09459
      Location:632686
      LIM3_ENH; The third LIM domain of the Enigma Homolog (ENH) family
      PHA03307
      Location:150533
      PHA03307; transcriptional regulator ICP4; Provisional
      cd00992
      Location:1082
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam15936
      Location:214315
      DUF4749; Domain of unknown function (DUF4749)
    15. XM_006501738.2XP_006501801.1  PDZ and LIM domain protein 5 isoform X1

      Conserved Domains (6) summary
      cd09453
      Location:558609
      LIM1_ENH; The first LIM domain of the Enigma Homolog (ENH) family
      cd09457
      Location:617668
      LIM2_ENH; The second LIM domain of the Enigma Homolog (ENH) family
      cd09459
      Location:676730
      LIM3_ENH; The third LIM domain of the Enigma Homolog (ENH) family
      PHA03307
      Location:150540
      PHA03307; transcriptional regulator ICP4; Provisional
      cd00992
      Location:1082
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam15936
      Location:214315
      DUF4749; Domain of unknown function (DUF4749)
    16. XM_006501751.4XP_006501814.1  PDZ and LIM domain protein 5 isoform X17

      See identical proteins and their annotated locations for XP_006501814.1

      UniProtKB/TrEMBL
      D9J303
      Related
      ENSMUSP00000059267.9, ENSMUST00000058626.9
      Conserved Domains (2) summary
      cd00992
      Location:1082
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam15936
      Location:105201
      DUF4749; Domain of unknown function (DUF4749)
    17. XM_006501750.4XP_006501813.1  PDZ and LIM domain protein 5 isoform X16

      See identical proteins and their annotated locations for XP_006501813.1

      UniProtKB/TrEMBL
      E9Q8P5
      Conserved Domains (2) summary
      cd00992
      Location:1082
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam15936
      Location:105206
      DUF4749; Domain of unknown function (DUF4749)
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