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    Scoc short coiled-coil protein [ Mus musculus (house mouse) ]

    Gene ID: 56367, updated on 27-Jan-2018

    Summary

    Official Symbol
    Scocprovided by MGI
    Official Full Name
    short coiled-coil proteinprovided by MGI
    Primary source
    MGI:MGI:1927654
    See related
    Ensembl:ENSMUSG00000063253 Vega:OTTMUSG00000061552
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    SCOCO; AA415030; 0610011C06Rik; 2810002J11Rik
    Expression
    Biased expression in CNS E18 (RPKM 38.4), frontal lobe adult (RPKM 34.5) and 14 other tissues See more
    Orthologs

    Genomic context

    See Scoc in Genome Data Viewer
    Location:
    8; 8 C2
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 8 NC_000074.6 (83434492..83458439, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 8 NC_000074.5 (85958392..85982290, complement)

    Chromosome 8 - NC_000074.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 32377 Neighboring gene calmegin Neighboring gene pescadillo homolog pseudogene Neighboring gene predicted gene, 33242

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Pathways from BioSystems

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    positive regulation of macroautophagy ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of protein complex stability ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
     
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    colocalizes_with endosome ISO
    Inferred from Sequence Orthology
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    colocalizes_with trans-Golgi network ISO
    Inferred from Sequence Orthology
    more info
     

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001039137.3NP_001034226.1  short coiled-coil protein isoform a

      See identical proteins and their annotated locations for NP_001034226.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the longest protein (isoform a).
      Source sequence(s)
      AC155304, AU042937, BC092071, BC147069
      Consensus CDS
      CCDS22453.1
      UniProtKB/Swiss-Prot
      Q78YZ6
      Related
      ENSMUSP00000080221.3, OTTMUSP00000077847, ENSMUST00000081506.10, OTTMUST00000150153
      Conserved Domains (1) summary
      pfam10224
      Location:45116
      DUF2205; Predicted coiled-coil protein (DUF2205)
    2. NM_001285992.1NP_001272921.1  short coiled-coil protein isoform c

      See identical proteins and their annotated locations for NP_001272921.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) represents use of an alternate promotor, differs in the 5' UTR, and initiates translation from a downstream start codon compared to variant 1. The resulting protein (isoform c) is shorter and has a distinct N-terminus compared to isoform a.
      Source sequence(s)
      AK167488, AU042937, BC092071, BY251609
      Consensus CDS
      CCDS85570.1
      UniProtKB/Swiss-Prot
      Q78YZ6
      Related
      ENSMUSP00000128210.2, OTTMUSP00000077848, ENSMUST00000167525.2, OTTMUST00000150154
      Conserved Domains (1) summary
      pfam10224
      Location:272
      DUF2205; Predicted coiled-coil protein (DUF2205)
    3. NM_019708.4NP_062682.1  short coiled-coil protein isoform b

      See identical proteins and their annotated locations for NP_062682.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) represents use of an alternate promotor, differs in the 5' UTR, and initiates translation from a downstream start codon compared to variant 1. The resulting protein (isoform b) is shorter and has a distinct N-terminus compared to isoform a.
      Source sequence(s)
      AU042937, BC092071, BY251609
      Consensus CDS
      CCDS52608.1
      UniProtKB/Swiss-Prot
      Q78YZ6
      Related
      ENSMUSP00000148647.1, OTTMUSP00000077849, ENSMUST00000212031.1, OTTMUST00000150155
      Conserved Domains (1) summary
      pfam10224
      Location:273
      DUF2205; Predicted coiled-coil protein (DUF2205)

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000074.6 Reference GRCm38.p4 C57BL/6J

      Range
      83434492..83458439 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011248448.2XP_011246750.1  short coiled-coil protein isoform X1

      Conserved Domains (1) summary
      pfam10224
      Location:45115
      DUF2205; Predicted coiled-coil protein (DUF2205)
    2. XM_006531205.2XP_006531268.1  short coiled-coil protein isoform X3

      See identical proteins and their annotated locations for XP_006531268.1

      UniProtKB/Swiss-Prot
      Q78YZ6
      Conserved Domains (1) summary
      pfam10224
      Location:272
      DUF2205; Predicted coiled-coil protein (DUF2205)
    3. XM_006531204.3XP_006531267.1  short coiled-coil protein isoform X2

      See identical proteins and their annotated locations for XP_006531267.1

      UniProtKB/Swiss-Prot
      Q78YZ6
      Conserved Domains (1) summary
      pfam10224
      Location:273
      DUF2205; Predicted coiled-coil protein (DUF2205)
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