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    Ivd isovaleryl coenzyme A dehydrogenase [ Mus musculus (house mouse) ]

    Gene ID: 56357, updated on 22-Aug-2021

    Summary

    Official Symbol
    Ivdprovided by MGI
    Official Full Name
    isovaleryl coenzyme A dehydrogenaseprovided by MGI
    Primary source
    MGI:MGI:1929242
    See related
    Ensembl:ENSMUSG00000027332
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    AI463340; 1300016K07Rik; 6720455E18Rik
    Expression
    Ubiquitous expression in adrenal adult (RPKM 99.3), heart adult (RPKM 88.5) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Ivd in Genome Data Viewer
    Location:
    2; 2 E5
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (118692440..118713390)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (118861959..118882909)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (118687736..118707093)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene predicted gene, 38629 Neighboring gene kinetochore-localized astrin/SPAG5 binding Neighboring gene predicted gene, 39913 Neighboring gene predicted gene, 32798 Neighboring gene predicted gene, 32957 Neighboring gene bromo adjacent homology domain containing 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables acyl-CoA dehydrogenase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables butyryl-CoA dehydrogenase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables flavin adenine dinucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables isovaleryl-CoA dehydrogenase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables isovaleryl-CoA dehydrogenase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables oxidoreductase activity, acting on the CH-CH group of donors IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in branched-chain amino acid catabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in fatty acid beta-oxidation using acyl-CoA dehydrogenase ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in leucine catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in leucine catabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in mitochondrial matrix ISO
    Inferred from Sequence Orthology
    more info
     
    located_in mitochondrial membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in mitochondrion HDA PubMed 
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    isovaleryl-CoA dehydrogenase, mitochondrial
    Names
    butyryl-CoA dehydrogenase
    NP_062800.1
    XP_006499988.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_019826.4NP_062800.1  isovaleryl-CoA dehydrogenase, mitochondrial precursor

      See identical proteins and their annotated locations for NP_062800.1

      Status: VALIDATED

      Source sequence(s)
      AL772255
      Consensus CDS
      CCDS16586.1
      UniProtKB/Swiss-Prot
      Q9JHI5
      Related
      ENSMUSP00000028807.6, ENSMUST00000028807.6
      Conserved Domains (2) summary
      cd01156
      Location:42421
      IVD; Isovaleryl-CoA dehydrogenase
      PLN02519
      Location:43417
      PLN02519; isovaleryl-CoA dehydrogenase

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      118692440..118713390
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006499925.1XP_006499988.1  isovaleryl-CoA dehydrogenase, mitochondrial isoform X1

      Conserved Domains (1) summary
      cd01156
      Location:42386
      IVD; Isovaleryl-CoA dehydrogenase
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