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    Arl3 ADP-ribosylation factor-like 3 [ Mus musculus (house mouse) ]

    Gene ID: 56350, updated on 31-Jan-2019

    Summary

    Official Symbol
    Arl3provided by MGI
    Official Full Name
    ADP-ribosylation factor-like 3provided by MGI
    Primary source
    MGI:MGI:1929699
    See related
    Ensembl:ENSMUSG00000025035
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Expression
    Broad expression in testis adult (RPKM 63.8), CNS E18 (RPKM 46.9) and 20 other tissues See more
    Orthologs

    Genomic context

    See Arl3 in Genome Data Viewer
    Location:
    19; 19 C3
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 19 NC_000085.6 (46531105..46573181, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 19 NC_000085.5 (46605599..46647575, complement)

    Chromosome 19 - NC_000085.6Genomic Context describing neighboring genes Neighboring gene SUFU negative regulator of hedgehog signaling Neighboring gene tripartite motif-containing 8 Neighboring gene sideroflexin 2 Neighboring gene WW domain binding protein 1 like

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    GDP binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    GDP binding ISO
    Inferred from Sequence Orthology
    more info
     
    GTP binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    GTP binding ISO
    Inferred from Sequence Orthology
    more info
     
    GTPase activating protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    GTPase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    magnesium ion binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    microtubule binding ISO
    Inferred from Sequence Orthology
    more info
     
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    Golgi to plasma membrane transport IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    cell division IEA
    Inferred from Electronic Annotation
    more info
     
    cilium assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cilium assembly ISO
    Inferred from Sequence Orthology
    more info
     
    intraciliary transport IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    kidney development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    mitotic cytokinesis ISO
    Inferred from Sequence Orthology
    more info
     
    photoreceptor cell development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    post-Golgi vesicle-mediated transport ISO
    Inferred from Sequence Orthology
    more info
     
    protein localization to ciliary membrane IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    protein localization to cilium ISO
    Inferred from Sequence Orthology
    more info
     
    protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    small GTPase mediated signal transduction ISO
    Inferred from Sequence Orthology
    more info
     
    smoothened signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
     
    axoneme IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cell projection IEA
    Inferred from Electronic Annotation
    more info
     
    centrosome ISO
    Inferred from Sequence Orthology
    more info
     
    ciliary basal body IDA
    Inferred from Direct Assay
    more info
    PubMed 
    ciliary transition zone IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    cytoplasmic microtubule ISO
    Inferred from Sequence Orthology
    more info
     
    cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    microtubule cytoskeleton IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    midbody ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    photoreceptor connecting cilium ISO
    Inferred from Sequence Orthology
    more info
     
    spindle microtubule ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    ADP-ribosylation factor-like protein 3
    Names
    ADP-ribosylation-like 3

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001355233.1NP_001342162.1  ADP-ribosylation factor-like protein 3 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC156982
      Conserved Domains (1) summary
      cd04155
      Location:3168
      Arl3; Arf-like 3 (Arl3) GTPase
    2. NM_019718.3NP_062692.1  ADP-ribosylation factor-like protein 3 isoform 1

      See identical proteins and their annotated locations for NP_062692.1

      Status: VALIDATED

      Source sequence(s)
      AC156982
      Consensus CDS
      CCDS38010.1
      UniProtKB/Swiss-Prot
      Q9WUL7
      UniProtKB/TrEMBL
      Q543P7
      Related
      ENSMUSP00000026009.8, ENSMUST00000026009.8
      Conserved Domains (1) summary
      cd04155
      Location:3176
      Arl3; Arf-like 3 (Arl3) GTPase

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000085.6 Reference GRCm38.p4 C57BL/6J

      Range
      46531105..46573181 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006527223.2XP_006527286.1  ADP-ribosylation factor-like protein 3 isoform X1

      Conserved Domains (1) summary
      cd04155
      Location:3168
      Arl3; Arf-like 3 (Arl3) GTPase
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