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    Tmed2 transmembrane p24 trafficking protein 2 [ Mus musculus (house mouse) ]

    Gene ID: 56334, updated on 5-Aug-2018

    Summary

    Official Symbol
    Tmed2provided by MGI
    Official Full Name
    transmembrane p24 trafficking protein 2provided by MGI
    Primary source
    MGI:MGI:1929269
    See related
    Ensembl:ENSMUSG00000029390 Vega:OTTMUSG00000024462
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Rnp24; Sid394; p24beta1; 1110032D12Rik; 1810020N21Rik
    Expression
    Ubiquitous expression in placenta adult (RPKM 136.3), ovary adult (RPKM 134.4) and 28 other tissues See more
    Orthologs

    Genomic context

    See Tmed2 in Genome Data Viewer
    Location:
    5; 5 F
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 5 NC_000071.6 (124540791..124550503)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 5 NC_000071.5 (124990800..125000512)

    Chromosome 5 - NC_000071.6Genomic Context describing neighboring genes Neighboring gene small nuclear ribonucleoprotein 35 (U11/U12) Neighboring gene Rab interacting lysosomal protein-like 1 Neighboring gene ribosomal protein L32 5C pseudogene Neighboring gene DEAD (Asp-Glu-Ala-Asp) box polypeptide 55 Neighboring gene eukaryotic translation initiation factor 2B, subunit 1 (alpha)

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 
    • Chemically induced (ENU) (1)  1 citation

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC102446

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    ER to Golgi vesicle-mediated transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Golgi organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    embryonic morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    embryonic placenta development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    heart looping IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    in utero embryonic development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    intracellular protein transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    labyrinthine layer blood vessel development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    maternal placenta development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    multicellular organism growth IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    neural tube closure IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of gene expression IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    post-anal tail morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    somite rostral/caudal axis specification IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    somitogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    COPI-coated vesicle ISO
    Inferred from Sequence Orthology
    more info
     
    COPII-coated ER to Golgi transport vesicle IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
     
    endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
     
    endoplasmic reticulum-Golgi intermediate compartment IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    endoplasmic reticulum-Golgi intermediate compartment ISO
    Inferred from Sequence Orthology
    more info
     
    integral component of membrane ISO
    Inferred from Sequence Orthology
    more info
     
    intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
     
    zymogen granule membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    transmembrane emp24 domain-containing protein 2
    Names
    COPI-coated vesicle membrane protein p24
    Sid394p
    coated vesicle membrane protein
    membrane protein p24A
    p24 family protein beta-1
    sid 394
    transmembrane emp24 domain trafficking protein 2

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_019770.2NP_062744.1  transmembrane emp24 domain-containing protein 2 precursor

      See identical proteins and their annotated locations for NP_062744.1

      Status: PROVISIONAL

      Source sequence(s)
      BC083140
      Consensus CDS
      CCDS19679.1
      UniProtKB/Swiss-Prot
      Q9R0Q3
      UniProtKB/TrEMBL
      A2RS53
      Related
      ENSMUSP00000054834.4, OTTMUSP00000029237, ENSMUST00000060226.10, OTTMUST00000059995
      Conserved Domains (1) summary
      pfam01105
      Location:20196
      EMP24_GP25L; emp24/gp25L/p24 family/GOLD

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000071.6 Reference GRCm38.p4 C57BL/6J

      Range
      124540791..124550503
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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