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    Sinhcaf SIN3-HDAC complex associated factor [ Mus musculus (house mouse) ]

    Gene ID: 56306, updated on 5-Aug-2018

    Summary

    Official Symbol
    Sinhcafprovided by MGI
    Official Full Name
    SIN3-HDAC complex associated factorprovided by MGI
    Primary source
    MGI:MGI:1929091
    See related
    Ensembl:ENSMUSG00000039985 Vega:OTTMUSG00000024045
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Tera; Ppcs1; Fam60a; Pptcs1
    Expression
    Biased expression in CNS E11.5 (RPKM 31.1), CNS E14 (RPKM 11.8) and 12 other tissues See more
    Orthologs

    Genomic context

    See Sinhcaf in Genome Data Viewer
    Location:
    6; 6 G3
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 6 NC_000072.6 (148921057..148946432, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 6 NC_000072.5 (148869579..148894954, complement)

    Chromosome 6 - NC_000072.6Genomic Context describing neighboring genes Neighboring gene caprin family member 2 Neighboring gene ribosomal protein S29 pseudogene Neighboring gene RIKEN cDNA 3010003L21 gene Neighboring gene DENN/MADD domain containing 5B Neighboring gene 60S ribosomal protein L27 pseudogene Neighboring gene cytochrome c, somatic pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    negative regulation of cell differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of cell migration IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    negative regulation of cell migration ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of cell proliferation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    Sin3 complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Sin3 complex ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    SIN3-HDAC complex-associated factor; protein FAM60A
    Names
    family with sequence similarity 60, member A
    pluripotent cell-specific 1
    teratocarcinoma expressed, serine rich

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001355645.1NP_001342574.1  SIN3-HDAC complex-associated factor isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC140327
      Conserved Domains (1) summary
      pfam15396
      Location:2198
      FAM60A; Protein Family FAM60A
    2. NM_001361398.1NP_001348327.1  SIN3-HDAC complex-associated factor isoform 2

      Status: VALIDATED

      Source sequence(s)
      AK145384, AK166569, BC076599, BU697039, BY029378, CD560982
      Conserved Domains (1) summary
      pfam15396
      Location:296
      FAM60A; Protein Family FAM60A
    3. NM_019643.4NP_062617.2  SIN3-HDAC complex-associated factor isoform 1

      See identical proteins and their annotated locations for NP_062617.2

      Status: VALIDATED

      Source sequence(s)
      AC140327
      Consensus CDS
      CCDS20713.1
      UniProtKB/Swiss-Prot
      Q8C8M1
      Related
      ENSMUSP00000050952.8, OTTMUSP00000028527, ENSMUST00000054080.14
      Conserved Domains (1) summary
      pfam15396
      Location:2198
      FAM60A; Protein Family FAM60A

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000072.6 Reference GRCm38.p4 C57BL/6J

      Range
      148921057..148946432 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006507074.3XP_006507137.1  protein FAM60A isoform X2

      See identical proteins and their annotated locations for XP_006507137.1

      UniProtKB/Swiss-Prot
      Q8C8M1
      Conserved Domains (1) summary
      pfam15396
      Location:2198
      FAM60A; Protein Family FAM60A
    2. XM_006507073.3XP_006507136.1  protein FAM60A isoform X1

    3. XM_006507075.2XP_006507138.1  protein FAM60A isoform X2

      See identical proteins and their annotated locations for XP_006507138.1

      UniProtKB/Swiss-Prot
      Q8C8M1
      Related
      ENSMUSP00000107187.1, OTTMUSP00000028532, ENSMUST00000111562.7, OTTMUST00000058790
      Conserved Domains (1) summary
      pfam15396
      Location:2198
      FAM60A; Protein Family FAM60A
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