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    Arl6 ADP-ribosylation factor-like 6 [ Mus musculus (house mouse) ]

    Gene ID: 56297, updated on 31-Jan-2019

    Summary

    Official Symbol
    Arl6provided by MGI
    Official Full Name
    ADP-ribosylation factor-like 6provided by MGI
    Primary source
    MGI:MGI:1927136
    See related
    Ensembl:ENSMUSG00000022722
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    BBS3; 1110018H24Rik; 2210411E14Rik
    Expression
    Broad expression in CNS E18 (RPKM 9.1), CNS E14 (RPKM 7.1) and 21 other tissues See more
    Orthologs

    Genomic context

    See Arl6 in Genome Data Viewer
    Location:
    16; 16 C1.3
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 16 NC_000082.6 (59613321..59639411, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 16 NC_000082.5 (59613147..59639165, complement)

    Chromosome 16 - NC_000082.6Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 1700022E09 gene Neighboring gene ribosomal oxygenase 2 Neighboring gene beta-gamma crystallin domain containing 3 Neighboring gene RIKEN cDNA 4930547E14 gene Neighboring gene Eph receptor A6 Neighboring gene ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c (subunit 9), isoform 1 pseudogene Neighboring gene uncharacterized LOC102636664

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    GTP binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    GTP binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    Ras protein signal transduction ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    Wnt signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    brain development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    cell projection organization IEA
    Inferred from Electronic Annotation
    more info
     
    cilium assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cilium assembly IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    cilium assembly ISO
    Inferred from Sequence Orthology
    more info
     
    fat cell differentiation IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    intracellular protein transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    protein ADP-ribosylation ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    protein localization to ciliary membrane ISO
    Inferred from Sequence Orthology
    more info
     
    protein localization to cilium IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    protein localization to cilium ISO
    Inferred from Sequence Orthology
    more info
     
    protein localization to non-motile cilium IDA
    Inferred from Direct Assay
    more info
    PubMed 
    protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    protein transport from ciliary membrane to plasma membrane IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of smoothened signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    retina layer formation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    vesicle-mediated transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    axoneme IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cell projection IEA
    Inferred from Electronic Annotation
    more info
     
    cilium ISO
    Inferred from Sequence Orthology
    more info
     
    cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    cytosol IDA
    Inferred from Direct Assay
    more info
    PubMed 
    membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    ADP-ribosylation factor-like protein 6
    Names
    ADP-ribosylation-like 6
    ADP-ribosylation-like factor homolog ARL6

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001347244.1NP_001334173.1  ADP-ribosylation factor-like protein 6 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC154473, AK003778, AK158832
      Consensus CDS
      CCDS84248.1
      UniProtKB/Swiss-Prot
      O88848
    2. NM_019665.3NP_062639.3  ADP-ribosylation factor-like protein 6 isoform 1

      See identical proteins and their annotated locations for NP_062639.3

      Status: VALIDATED

      Source sequence(s)
      AK160666, BY279441, CO040545
      Consensus CDS
      CCDS28259.1
      UniProtKB/Swiss-Prot
      O88848
      UniProtKB/TrEMBL
      Q3TUM2
      Related
      ENSMUSP00000023405.9, ENSMUST00000023405.15
      Conserved Domains (2) summary
      smart00178
      Location:11181
      SAR; Sar1p-like members of the Ras-family of small GTPases
      cd04157
      Location:19180
      Arl6; Arf-like 6 (Arl6) GTPase

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000082.6 Reference GRCm38.p4 C57BL/6J

      Range
      59613321..59639411 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006522398.3XP_006522461.1  ADP-ribosylation factor-like protein 6 isoform X1

      Related
      ENSMUSP00000097238.3, ENSMUST00000099646.9
      Conserved Domains (2) summary
      smart00178
      Location:11179
      SAR; Sar1p-like members of the Ras-family of small GTPases
      cd04157
      Location:19180
      Arl6; Arf-like 6 (Arl6) GTPase
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