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    Higd1a HIG1 domain family, member 1A [ Mus musculus (house mouse) ]

    Gene ID: 56295, updated on 5-Aug-2018

    Summary

    Official Symbol
    Higd1aprovided by MGI
    Official Full Name
    HIG1 domain family, member 1Aprovided by MGI
    Primary source
    MGI:MGI:1930666
    See related
    Ensembl:ENSMUSG00000038412 Vega:OTTMUSG00000062673
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Hig1; HIMP1; AI303276; AW049839; 2210020B17Rik; 7420700H20Rik
    Expression
    Ubiquitous expression in cerebellum adult (RPKM 19.8), frontal lobe adult (RPKM 17.3) and 28 other tissues See more
    Orthologs

    Genomic context

    See Higd1a in Genome Data Viewer
    Location:
    9; 9 F4
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 9 NC_000075.6 (121848560..121858357, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 9 NC_000075.5 (121757678..121767118, complement)

    Chromosome 9 - NC_000075.6Genomic Context describing neighboring genes Neighboring gene kelch-like 40 Neighboring gene hedgehog acyltransferase-like Neighboring gene coiled-coil domain containing 13 Neighboring gene atypical chemokine receptor 2 Neighboring gene cytochrome P450, family 8, subfamily b, polypeptide 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    molecular_function ND
    No biological Data available
    more info
     
    Component Evidence Code Pubs
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    mitochondrial inner membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    mitochondrion HDA PubMed 
    mitochondrion IDA
    Inferred from Direct Assay
    more info
    PubMed 
    mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     
    nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    protein-containing complex ISO
    Inferred from Sequence Orthology
    more info
     
    respiratory chain IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    HIG1 domain family member 1A, mitochondrial
    Names
    hypoxia induced gene 1
    hypoxia-inducible gene 1 protein

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001357837.1NP_001344766.1  HIG1 domain family member 1A, mitochondrial

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript. All six variants encode the same protein.
      Source sequence(s)
      AC165080, AI303276, AK018360, BE457620, CJ042199
      Conserved Domains (1) summary
      pfam04588
      Location:2876
      HIG_1_N; Hypoxia induced protein conserved region
    2. NM_001357838.1NP_001344767.1  HIG1 domain family member 1A, mitochondrial

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. All six variants encode the same protein.
      Source sequence(s)
      AA414831, AI303276, AK018360, BE457620
      Conserved Domains (1) summary
      pfam04588
      Location:2876
      HIG_1_N; Hypoxia induced protein conserved region
    3. NM_001357839.1NP_001344768.1  HIG1 domain family member 1A, mitochondrial

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. All six variants encode the same protein.
      Source sequence(s)
      AI303276, AK018360, BE457620, CJ042267
      Conserved Domains (1) summary
      pfam04588
      Location:2876
      HIG_1_N; Hypoxia induced protein conserved region
    4. NM_001357840.1NP_001344769.1  HIG1 domain family member 1A, mitochondrial

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) differs in the 5' UTR compared to variant 1. All six variants encode the same protein.
      Source sequence(s)
      AI303276, AK018360, BE457620, BE689839
      Conserved Domains (1) summary
      pfam04588
      Location:2876
      HIG_1_N; Hypoxia induced protein conserved region
    5. NM_001357841.1NP_001344770.1  HIG1 domain family member 1A, mitochondrial

      Status: VALIDATED

      Description
      Transcript Variant: This variant (6) differs in the 5' UTR compared to variant 1. All six variants encode the same protein.
      Source sequence(s)
      AI303276, AK018360, BE457620, BU851504
      Conserved Domains (1) summary
      pfam04588
      Location:2876
      HIG_1_N; Hypoxia induced protein conserved region
    6. NM_019814.5NP_062788.1  HIG1 domain family member 1A, mitochondrial

      See identical proteins and their annotated locations for NP_062788.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (5) differs in the 5' UTR compared to variant 1. All six variants encode the same protein.
      Source sequence(s)
      AI303276, AK018360, BE457620
      Consensus CDS
      CCDS40812.1
      UniProtKB/Swiss-Prot
      Q9JLR9
      UniProtKB/TrEMBL
      Q1XG81
      Related
      ENSMUSP00000054881.6, OTTMUSP00000079119, ENSMUST00000060251.7
      Conserved Domains (1) summary
      pfam04588
      Location:2876
      HIG_1_N; Hypoxia induced protein conserved region

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000075.6 Reference GRCm38.p4 C57BL/6J

      Range
      121848560..121858357 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006512201.1XP_006512264.1  HIG1 domain family member 1A, mitochondrial isoform X1

      UniProtKB/Swiss-Prot
      Q9JLR9
      UniProtKB/TrEMBL
      Q1XG81
      Related
      ENSMUSP00000149531.1, OTTMUSP00000079121, ENSMUST00000213124.1, OTTMUST00000152662
      Conserved Domains (1) summary
      pfam04588
      Location:2876
      HIG_1_N; Hypoxia induced protein conserved region
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