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    Rev1 REV1, DNA directed polymerase [ Mus musculus (house mouse) ]

    Gene ID: 56210, updated on 23-Jun-2021

    Summary

    Official Symbol
    Rev1provided by MGI
    Official Full Name
    REV1, DNA directed polymeraseprovided by MGI
    Primary source
    MGI:MGI:1929074
    See related
    Ensembl:ENSMUSG00000026082
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    RE; Rev1l; AU022044; 1110027I23Rik
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 8.2), CNS E14 (RPKM 7.3) and 27 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Rev1 in Genome Data Viewer
    Location:
    1; 1 B
    Exon count:
    28
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (38091867..38169191, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (38052786..38129921, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 1 NC_000067.5 (38109631..38186507, complement)

    Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene thioredoxin domain containing 9 Neighboring gene eukaryotic translation initiation factor 5B Neighboring gene predicted gene, 34448 Neighboring gene predicted gene 5099 Neighboring gene AF4/FMR2 family, member 3 Neighboring gene predicted gene 16150

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC66950

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables DNA-directed DNA polymerase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables damaged DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables deoxycytidyl transferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables deoxycytidyl transferase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables nucleotidyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within DNA biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within DNA repair IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in DNA repair IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within cellular response to DNA damage stimulus IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in error-free translesion synthesis IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in error-prone translesion synthesis IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within error-prone translesion synthesis IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in response to UV ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    DNA repair protein REV1
    Names
    REV1 homolog
    rev1-like terminal deoxycytidyl transferase
    NP_001346216.1
    NP_001346217.1
    NP_062516.2
    XP_006496216.2
    XP_006496217.2
    XP_006496218.2
    XP_006496219.1
    XP_006496224.1
    XP_006496225.1
    XP_017177324.1
    XP_017177325.1
    XP_030111499.1
    XP_030111501.1
    XP_036008367.1
    XP_036008368.1
    XP_036008369.1
    XP_036008370.1
    XP_036008371.1
    XP_036008372.1
    XP_036008373.1
    XP_036008374.1
    XP_036008375.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001359287.1NP_001346216.1  DNA repair protein REV1 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC114583
      Conserved Domains (3) summary
      cd01701
      Location:16333
      PolY_Rev1; DNA polymerase Rev1
      cd12145
      Location:666759
      Rev1_C; C-terminal domain of the Y-family polymerase Rev1
      cd19318
      Location:516551
      Rev1_UBM2; Ubiquitin-Binding Motif 2 (UBM2) of Y-family polymerase Rev1
    2. NM_001359288.1NP_001346217.1  DNA repair protein REV1 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC114583
      Conserved Domains (3) summary
      cd12145
      Location:634727
      Rev1_C; C-terminal domain of the Y-family polymerase Rev1
      cd19318
      Location:484519
      Rev1_UBM2; Ubiquitin-Binding Motif 2 (UBM2) of Y-family polymerase Rev1
      cl28996
      Location:1301
      PolY; Y-family of DNA polymerases
    3. NM_019570.4NP_062516.2  DNA repair protein REV1 isoform 1

      See identical proteins and their annotated locations for NP_062516.2

      Status: VALIDATED

      Source sequence(s)
      AK048838, BC058093
      Consensus CDS
      CCDS14899.1
      UniProtKB/Swiss-Prot
      Q920Q2
      Related
      ENSMUSP00000027251.7, ENSMUST00000027251.12
      Conserved Domains (4) summary
      cd01701
      Location:346822
      PolY_Rev1; DNA polymerase Rev1
      cd12145
      Location:11551248
      Rev1_C; C-terminal domain of the Y-family polymerase Rev1
      cd17719
      Location:48131
      BRCT_Rev1; BRCT domain of DNA repair protein Rev1 and similar proteins
      cd19318
      Location:10051040
      Rev1_UBM2; Ubiquitin-Binding Motif 2 (UBM2) of Y-family polymerase Rev1

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000067.7 Reference GRCm39 C57BL/6J

      Range
      38091867..38169191 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030255641.2XP_030111501.1  DNA repair protein REV1 isoform X3

      Conserved Domains (4) summary
      cd01701
      Location:346812
      PolY_Rev1; DNA polymerase Rev1
      cd12145
      Location:11451238
      Rev1_C; C-terminal domain of the Y-family polymerase Rev1
      cd17719
      Location:48131
      BRCT_Rev1; BRCT domain of DNA repair protein Rev1 and similar proteins
      cd19318
      Location:9951030
      Rev1_UBM2; Ubiquitin-Binding Motif 2 (UBM2) of Y-family polymerase Rev1
    2. XM_036152478.1XP_036008371.1  DNA repair protein REV1 isoform X2

      Conserved Domains (4) summary
      cd01701
      Location:346821
      PolY_Rev1; DNA polymerase Rev1
      cd12145
      Location:11541247
      Rev1_C; C-terminal domain of the Y-family polymerase Rev1
      cd17719
      Location:48131
      BRCT_Rev1; BRCT domain of DNA repair protein Rev1 and similar proteins
      cd19318
      Location:10041039
      Rev1_UBM2; Ubiquitin-Binding Motif 2 (UBM2) of Y-family polymerase Rev1
    3. XM_006496155.5XP_006496218.2  DNA repair protein REV1 isoform X3

      Conserved Domains (4) summary
      cd01701
      Location:346812
      PolY_Rev1; DNA polymerase Rev1
      cd12145
      Location:11451238
      Rev1_C; C-terminal domain of the Y-family polymerase Rev1
      cd17719
      Location:48131
      BRCT_Rev1; BRCT domain of DNA repair protein Rev1 and similar proteins
      cd19318
      Location:9951030
      Rev1_UBM2; Ubiquitin-Binding Motif 2 (UBM2) of Y-family polymerase Rev1
    4. XM_036152474.1XP_036008367.1  DNA repair protein REV1 isoform X5

      Conserved Domains (4) summary
      cd01701
      Location:346779
      PolY_Rev1; DNA polymerase Rev1
      cd12145
      Location:11121205
      Rev1_C; C-terminal domain of the Y-family polymerase Rev1
      cd17719
      Location:48131
      BRCT_Rev1; BRCT domain of DNA repair protein Rev1 and similar proteins
      cd19318
      Location:962997
      Rev1_UBM2; Ubiquitin-Binding Motif 2 (UBM2) of Y-family polymerase Rev1
    5. XM_006496154.5XP_006496217.2  DNA repair protein REV1 isoform X2

      Conserved Domains (4) summary
      cd01701
      Location:346821
      PolY_Rev1; DNA polymerase Rev1
      cd12145
      Location:11541247
      Rev1_C; C-terminal domain of the Y-family polymerase Rev1
      cd17719
      Location:48131
      BRCT_Rev1; BRCT domain of DNA repair protein Rev1 and similar proteins
      cd19318
      Location:10041039
      Rev1_UBM2; Ubiquitin-Binding Motif 2 (UBM2) of Y-family polymerase Rev1
    6. XM_006496153.5XP_006496216.2  DNA repair protein REV1 isoform X1

      Conserved Domains (4) summary
      cd01701
      Location:346822
      PolY_Rev1; DNA polymerase Rev1
      cd12145
      Location:11551248
      Rev1_C; C-terminal domain of the Y-family polymerase Rev1
      cd17719
      Location:48131
      BRCT_Rev1; BRCT domain of DNA repair protein Rev1 and similar proteins
      cd19318
      Location:10051040
      Rev1_UBM2; Ubiquitin-Binding Motif 2 (UBM2) of Y-family polymerase Rev1
    7. XM_036152475.1XP_036008368.1  DNA repair protein REV1 isoform X1

      Conserved Domains (4) summary
      cd01701
      Location:346822
      PolY_Rev1; DNA polymerase Rev1
      cd12145
      Location:11551248
      Rev1_C; C-terminal domain of the Y-family polymerase Rev1
      cd17719
      Location:48131
      BRCT_Rev1; BRCT domain of DNA repair protein Rev1 and similar proteins
      cd19318
      Location:10051040
      Rev1_UBM2; Ubiquitin-Binding Motif 2 (UBM2) of Y-family polymerase Rev1
    8. XM_036152479.1XP_036008372.1  DNA repair protein REV1 isoform X2

      Conserved Domains (4) summary
      cd01701
      Location:346821
      PolY_Rev1; DNA polymerase Rev1
      cd12145
      Location:11541247
      Rev1_C; C-terminal domain of the Y-family polymerase Rev1
      cd17719
      Location:48131
      BRCT_Rev1; BRCT domain of DNA repair protein Rev1 and similar proteins
      cd19318
      Location:10041039
      Rev1_UBM2; Ubiquitin-Binding Motif 2 (UBM2) of Y-family polymerase Rev1
    9. XM_030255639.2XP_030111499.1  DNA repair protein REV1 isoform X1

      Conserved Domains (4) summary
      cd01701
      Location:346822
      PolY_Rev1; DNA polymerase Rev1
      cd12145
      Location:11551248
      Rev1_C; C-terminal domain of the Y-family polymerase Rev1
      cd17719
      Location:48131
      BRCT_Rev1; BRCT domain of DNA repair protein Rev1 and similar proteins
      cd19318
      Location:10051040
      Rev1_UBM2; Ubiquitin-Binding Motif 2 (UBM2) of Y-family polymerase Rev1
    10. XM_006496156.4XP_006496219.1  DNA repair protein REV1 isoform X4

      Conserved Domains (4) summary
      cd01701
      Location:361837
      PolY_Rev1; DNA polymerase Rev1
      cd12145
      Location:11701263
      Rev1_C; C-terminal domain of the Y-family polymerase Rev1
      cd17719
      Location:63146
      BRCT_Rev1; BRCT domain of DNA repair protein Rev1 and similar proteins
      pfam14377
      Location:948969
      DUF4414; Domain of unknown function (DUF4414)
    11. XM_036152481.1XP_036008374.1  DNA repair protein REV1 isoform X7

      Conserved Domains (3) summary
      cd12145
      Location:634727
      Rev1_C; C-terminal domain of the Y-family polymerase Rev1
      cd19318
      Location:484519
      Rev1_UBM2; Ubiquitin-Binding Motif 2 (UBM2) of Y-family polymerase Rev1
      cl28996
      Location:1301
      PolY; Y-family of DNA polymerases
    12. XM_036152477.1XP_036008370.1  DNA repair protein REV1 isoform X1

      Conserved Domains (4) summary
      cd01701
      Location:346822
      PolY_Rev1; DNA polymerase Rev1
      cd12145
      Location:11551248
      Rev1_C; C-terminal domain of the Y-family polymerase Rev1
      cd17719
      Location:48131
      BRCT_Rev1; BRCT domain of DNA repair protein Rev1 and similar proteins
      cd19318
      Location:10051040
      Rev1_UBM2; Ubiquitin-Binding Motif 2 (UBM2) of Y-family polymerase Rev1
    13. XM_036152476.1XP_036008369.1  DNA repair protein REV1 isoform X1

      Conserved Domains (4) summary
      cd01701
      Location:346822
      PolY_Rev1; DNA polymerase Rev1
      cd12145
      Location:11551248
      Rev1_C; C-terminal domain of the Y-family polymerase Rev1
      cd17719
      Location:48131
      BRCT_Rev1; BRCT domain of DNA repair protein Rev1 and similar proteins
      cd19318
      Location:10051040
      Rev1_UBM2; Ubiquitin-Binding Motif 2 (UBM2) of Y-family polymerase Rev1
    14. XM_006496161.3XP_006496224.1  DNA repair protein REV1 isoform X6

      Conserved Domains (3) summary
      cd01701
      Location:16333
      PolY_Rev1; DNA polymerase Rev1
      cd12145
      Location:666759
      Rev1_C; C-terminal domain of the Y-family polymerase Rev1
      cd19318
      Location:516551
      Rev1_UBM2; Ubiquitin-Binding Motif 2 (UBM2) of Y-family polymerase Rev1
    15. XM_017321835.2XP_017177324.1  DNA repair protein REV1 isoform X7

      Conserved Domains (3) summary
      cd12145
      Location:634727
      Rev1_C; C-terminal domain of the Y-family polymerase Rev1
      cd19318
      Location:484519
      Rev1_UBM2; Ubiquitin-Binding Motif 2 (UBM2) of Y-family polymerase Rev1
      cl28996
      Location:1301
      PolY; Y-family of DNA polymerases
    16. XM_017321836.2XP_017177325.1  DNA repair protein REV1 isoform X6

      Conserved Domains (3) summary
      cd01701
      Location:16333
      PolY_Rev1; DNA polymerase Rev1
      cd12145
      Location:666759
      Rev1_C; C-terminal domain of the Y-family polymerase Rev1
      cd19318
      Location:516551
      Rev1_UBM2; Ubiquitin-Binding Motif 2 (UBM2) of Y-family polymerase Rev1
    17. XM_006496162.2XP_006496225.1  DNA repair protein REV1 isoform X7

      See identical proteins and their annotated locations for XP_006496225.1

      Conserved Domains (3) summary
      cd12145
      Location:634727
      Rev1_C; C-terminal domain of the Y-family polymerase Rev1
      cd19318
      Location:484519
      Rev1_UBM2; Ubiquitin-Binding Motif 2 (UBM2) of Y-family polymerase Rev1
      cl28996
      Location:1301
      PolY; Y-family of DNA polymerases
    18. XM_036152480.1XP_036008373.1  DNA repair protein REV1 isoform X6

      Related
      ENSMUST00000194650.6
      Conserved Domains (3) summary
      cd01701
      Location:16333
      PolY_Rev1; DNA polymerase Rev1
      cd12145
      Location:666759
      Rev1_C; C-terminal domain of the Y-family polymerase Rev1
      cd19318
      Location:516551
      Rev1_UBM2; Ubiquitin-Binding Motif 2 (UBM2) of Y-family polymerase Rev1
    19. XM_036152482.1XP_036008375.1  DNA repair protein REV1 isoform X7

      Conserved Domains (3) summary
      cd12145
      Location:634727
      Rev1_C; C-terminal domain of the Y-family polymerase Rev1
      cd19318
      Location:484519
      Rev1_UBM2; Ubiquitin-Binding Motif 2 (UBM2) of Y-family polymerase Rev1
      cl28996
      Location:1301
      PolY; Y-family of DNA polymerases
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