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    Set SET nuclear oncogene [ Mus musculus (house mouse) ]

    Gene ID: 56086, updated on 5-Aug-2018

    Summary

    Official Symbol
    Setprovided by MGI
    Official Full Name
    SET nuclear oncogeneprovided by MGI
    Primary source
    MGI:MGI:1860267
    See related
    Ensembl:ENSMUSG00000054766 Vega:OTTMUSG00000016726
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    TAF-I; I-2PP2A; AA407739; StF-IT-1; 2610030F17Rik; 5730420M11Rik
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 163.2), CNS E14 (RPKM 62.3) and 28 other tissues See more
    Orthologs

    Genomic context

    See Set in Genome Data Viewer
    Location:
    2; 2 B
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 2 NC_000068.7 (30061996..30072577)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (29917563..29927315)

    Chromosome 2 - NC_000068.7Genomic Context describing neighboring genes Neighboring gene spectrin alpha, non-erythrocytic 1 Neighboring gene microRNA 6997 Neighboring gene WD repeat domain 34 Neighboring gene protein kinase N3 Neighboring gene zinc finger, DHHC domain containing 12 Neighboring gene zyg-11 related, cell cycle regulator

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC118419

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    negative regulation of neuron apoptotic process ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of transcription, DNA-templated ISO
    Inferred from Sequence Orthology
    more info
     
    nucleosome assembly IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
     
    lipid droplet ISO
    Inferred from Sequence Orthology
    more info
     
    nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    perinuclear region of cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    protein-containing complex ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    protein SET
    Names
    SET translocation
    phosphatase 2A inhibitor I2PP2A
    template-activating factor I

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001204875.1NP_001191804.1  protein SET isoform 2

      See identical proteins and their annotated locations for NP_001191804.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) encodes the shorter isoform (2; also known as isoform beta).
      Source sequence(s)
      AK019960, BQ899734, BU756940
      Consensus CDS
      CCDS57162.1
      UniProtKB/Swiss-Prot
      Q9EQU5
      Related
      ENSMUSP00000070002.6, OTTMUSP00000018147, ENSMUST00000067996.6, OTTMUST00000040609
      Conserved Domains (1) summary
      pfam00956
      Location:37221
      NAP; Nucleosome assembly protein (NAP)
    2. NM_023871.4NP_076360.1  protein SET isoform 1

      See identical proteins and their annotated locations for NP_076360.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the longer isoform (1; also known as isoform alpha).
      Source sequence(s)
      AK019960, BC103791, BE331951, BU756940
      Consensus CDS
      CCDS15866.1
      UniProtKB/Swiss-Prot
      Q9EQU5
      UniProtKB/TrEMBL
      Q3T9S3
      Related
      ENSMUSP00000099930.3, OTTMUSP00000018110, ENSMUST00000102866.9, OTTMUST00000040518
      Conserved Domains (1) summary
      pfam00956
      Location:49233
      NAP; Nucleosome assembly protein (NAP)

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000068.7 Reference GRCm38.p4 C57BL/6J

      Range
      30061996..30072577
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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