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    Nop58 NOP58 ribonucleoprotein [ Mus musculus (house mouse) ]

    Gene ID: 55989, updated on 12-Aug-2018

    Summary

    Official Symbol
    Nop58provided by MGI
    Official Full Name
    NOP58 ribonucleoproteinprovided by MGI
    Primary source
    MGI:MGI:1933184
    See related
    Ensembl:ENSMUSG00000026020 Vega:OTTMUSG00000047257
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    SIK; MSSP; Nol5; nop5
    Expression
    Broad expression in CNS E11.5 (RPKM 41.5), liver E14 (RPKM 35.5) and 20 other tissues See more
    Orthologs

    Genomic context

    See Nop58 in Genome Data Viewer
    Location:
    1; 1 C2
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 1 NC_000067.6 (59684951..59711510)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 1 NC_000067.5 (59741850..59768354)

    Chromosome 1 - NC_000067.6Genomic Context describing neighboring genes Neighboring gene predicted gene 973 Neighboring gene predicted gene, 33833 Neighboring gene small ubiquitin-like modifier 1 Neighboring gene small nucleolar RNA, C/D box 70 Neighboring gene small nucleolar RNA, C/D box 11 Neighboring gene bone morphogenetic protein receptor, type II (serine/threonine kinase) Neighboring gene family with sequence similarity 117, member B Neighboring gene arginyl-tRNA synthetase 2, mitochondrial pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC105209

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    ATPase binding ISO
    Inferred from Sequence Orthology
    more info
     
    TFIID-class transcription factor complex binding ISO
    Inferred from Sequence Orthology
    more info
     
    snoRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    snoRNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    ribosome biogenesis IEA
    Inferred from Electronic Annotation
    more info
     
    snoRNA localization ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    Cajal body ISO
    Inferred from Sequence Orthology
    more info
     
    box C/D snoRNP complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    fibrillar center ISO
    Inferred from Sequence Orthology
    more info
     
    nucleolus ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    pre-snoRNP complex ISO
    Inferred from Sequence Orthology
    more info
     
    small nucleolar ribonucleoprotein complex ISO
    Inferred from Sequence Orthology
    more info
     
    small-subunit processome IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    nucleolar protein 58
    Names
    NOP58 ribonucleoprotein homolog
    SIK similar protein
    nucleolar protein 5

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_018868.2NP_061356.2  nucleolar protein 58

      See identical proteins and their annotated locations for NP_061356.2

      Status: VALIDATED

      Source sequence(s)
      AK034577, AK044216, AK134286
      Consensus CDS
      CCDS35587.1
      UniProtKB/Swiss-Prot
      Q6DFW4
      Related
      ENSMUSP00000140250.1, OTTMUSP00000067100, ENSMUST00000191142.6, OTTMUST00000122181
      Conserved Domains (3) summary
      smart00931
      Location:162213
      NOSIC; NOSIC (NUC001) domain
      pfam01798
      Location:168396
      Nop; snoRNA binding domain, fibrillarin
      pfam08156
      Location:266
      NOP5NT; NOP5NT (NUC127) domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000067.6 Reference GRCm38.p4 C57BL/6J

      Range
      59684951..59711510
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006496149.2XP_006496212.1  nucleolar protein 58 isoform X1

      See identical proteins and their annotated locations for XP_006496212.1

      Conserved Domains (2) summary
      smart00931
      Location:99150
      NOSIC; NOSIC (NUC001) domain
      pfam01798
      Location:105333
      Nop; snoRNA binding domain, fibrillarin
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