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    Agpat1 1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha) [ Mus musculus (house mouse) ]

    Gene ID: 55979, updated on 23-Jun-2021

    Summary

    Official Symbol
    Agpat1provided by MGI
    Official Full Name
    1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha)provided by MGI
    Primary source
    MGI:MGI:1932075
    See related
    Ensembl:ENSMUSG00000034254
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1-A; Lpa; 1-AGP; 1-AGPAT; AW047140
    Expression
    Ubiquitous expression in duodenum adult (RPKM 284.0), testis adult (RPKM 273.5) and 27 other tissues See more
    Orthologs
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    Genomic context

    See Agpat1 in Genome Data Viewer
    Location:
    17 B1; 17 18.18 cM
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (34823169..34832423)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (34604195..34613449)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 17 NC_000083.5 (34742806..34750394)

    Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene advanced glycosylation end product-specific receptor Neighboring gene ring finger protein 5 Neighboring gene EGF-like domain 8 Neighboring gene palmitoyl-protein thioesterase 2 Neighboring gene proline-rich transmembrane protein 1 Neighboring gene FK506 binding protein-like

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables 1-acylglycerol-3-phosphate O-acyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables 1-acylglycerol-3-phosphate O-acyltransferase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables 1-acylglycerol-3-phosphate O-acyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables acyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
     
    located_in integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    1-acyl-sn-glycerol-3-phosphate acyltransferase alpha
    Names
    1-AGP acyltransferase 1
    1-AGPAT 1
    Lpaat-alpha
    lysophosphatidic acid acyltransferase alpha
    NP_001156851.1
    NP_061350.3
    XP_006524710.1
    XP_006524711.1
    XP_030105775.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001163379.1NP_001156851.1  1-acyl-sn-glycerol-3-phosphate acyltransferase alpha precursor

      See identical proteins and their annotated locations for NP_001156851.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein.
      Source sequence(s)
      CT009767
      Consensus CDS
      CCDS37590.1
      UniProtKB/Swiss-Prot
      O35083
      UniProtKB/TrEMBL
      A0A0R4J263
      Related
      ENSMUSP00000048573.9, ENSMUST00000037489.15
      Conserved Domains (1) summary
      cd07989
      Location:66253
      LPLAT_AGPAT-like; Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like
    2. NM_018862.3NP_061350.3  1-acyl-sn-glycerol-3-phosphate acyltransferase alpha precursor

      See identical proteins and their annotated locations for NP_061350.3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same protein.
      Source sequence(s)
      CT009767
      Consensus CDS
      CCDS37590.1
      UniProtKB/Swiss-Prot
      O35083
      UniProtKB/TrEMBL
      A0A0R4J263
      Related
      ENSMUSP00000109776.4, ENSMUST00000114140.10
      Conserved Domains (1) summary
      cd07989
      Location:66253
      LPLAT_AGPAT-like; Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000083.7 Reference GRCm39 C57BL/6J

      Range
      34823169..34832423
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006524647.3XP_006524710.1  1-acyl-sn-glycerol-3-phosphate acyltransferase alpha isoform X1

      See identical proteins and their annotated locations for XP_006524710.1

      UniProtKB/Swiss-Prot
      O35083
      UniProtKB/TrEMBL
      A0A0R4J263
      Conserved Domains (1) summary
      cd07989
      Location:66253
      LPLAT_AGPAT-like; Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like
    2. XM_006524648.2XP_006524711.1  1-acyl-sn-glycerol-3-phosphate acyltransferase alpha isoform X1

      See identical proteins and their annotated locations for XP_006524711.1

      UniProtKB/Swiss-Prot
      O35083
      UniProtKB/TrEMBL
      A0A0R4J263
      Conserved Domains (1) summary
      cd07989
      Location:66253
      LPLAT_AGPAT-like; Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like
    3. XM_030249915.1XP_030105775.1  1-acyl-sn-glycerol-3-phosphate acyltransferase alpha isoform X1

      Conserved Domains (1) summary
      cd07989
      Location:66253
      LPLAT_AGPAT-like; Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like
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