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    Ebag9 estrogen receptor-binding fragment-associated gene 9 [ Mus musculus (house mouse) ]

    Gene ID: 55960, updated on 26-Sep-2022

    Summary

    Official Symbol
    Ebag9provided by MGI
    Official Full Name
    estrogen receptor-binding fragment-associated gene 9provided by MGI
    Primary source
    MGI:MGI:1859920
    See related
    Ensembl:ENSMUSG00000022339 AllianceGenome:MGI:1859920
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Rcas1
    Summary
    Predicted to act upstream of or within apoptotic process. Predicted to be located in Golgi apparatus and membrane. Predicted to be integral component of membrane. Predicted to be active in secretory granule. Is expressed in several structures, including central nervous system; genitourinary system; liver; retina; and spleen. Human ortholog(s) of this gene implicated in breast cancer. Orthologous to human EBAG9 (estrogen receptor binding site associated antigen 9). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 3.4), bladder adult (RPKM 3.3) and 28 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Ebag9 in Genome Data Viewer
    Location:
    15; 15 B3.2
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (44482623..44504929)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (44619227..44641538)

    Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 22392 Neighboring gene ENY2 transcription and export complex 2 subunit Neighboring gene polycystic kidney and hepatic disease 1-like 1 Neighboring gene syntabulin (syntaxin-interacting) Neighboring gene RIKEN cDNA 2310069G16 gene Neighboring gene predicted gene, 33852

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (3)  1 citation
    • Endonuclease-mediated (2) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC118417

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    acts_upstream_of_or_within apoptotic process IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in secretory granule IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in secretory granule ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    receptor-binding cancer antigen expressed on SiSo cells
    Names
    cancer-associated surface antigen RCAS1
    estrogen receptor-binding fragment-associated gene 9 protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001357690.2NP_001344619.1  receptor-binding cancer antigen expressed on SiSo cells

      Status: VALIDATED

      Source sequence(s)
      AC128736
      Consensus CDS
      CCDS27457.1
      UniProtKB/Swiss-Prot
      Q9QYD0
      Related
      ENSMUSP00000154361.2, ENSMUST00000227691.2
      Conserved Domains (1) summary
      pfam07946
      Location:160203
      DUF1682; Protein of unknown function (DUF1682)
    2. NM_001357691.2NP_001344620.1  receptor-binding cancer antigen expressed on SiSo cells

      Status: VALIDATED

      Source sequence(s)
      AC128736
      Consensus CDS
      CCDS27457.1
      UniProtKB/Swiss-Prot
      Q9QYD0
      Related
      ENSMUSP00000153791.2, ENSMUST00000226165.2
      Conserved Domains (1) summary
      pfam07946
      Location:160203
      DUF1682; Protein of unknown function (DUF1682)
    3. NM_001411929.1NP_001398858.1  receptor-binding cancer antigen expressed on SiSo cells

      Status: VALIDATED

      Source sequence(s)
      AC128736
    4. NM_019480.6NP_062353.3  receptor-binding cancer antigen expressed on SiSo cells

      See identical proteins and their annotated locations for NP_062353.3

      Status: VALIDATED

      Source sequence(s)
      AC128736
      Consensus CDS
      CCDS27457.1
      UniProtKB/Swiss-Prot
      Q9D0V7, Q9QYD0
      Related
      ENSMUSP00000022964.8, ENSMUST00000022964.9
      Conserved Domains (1) summary
      pfam07946
      Location:160203
      DUF1682; Protein of unknown function (DUF1682)

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000081.7 Reference GRCm39 C57BL/6J

      Range
      44482623..44504929
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006521195.5XP_006521258.1  receptor-binding cancer antigen expressed on SiSo cells isoform X1

      UniProtKB/Swiss-Prot
      Q9D0V7, Q9QYD0
      Conserved Domains (1) summary
      pfam07946
      Location:160203
      DUF1682; Protein of unknown function (DUF1682)