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    Bri3 brain protein I3 [ Mus musculus (house mouse) ]

    Gene ID: 55950, updated on 26-Sep-2022

    Summary

    Official Symbol
    Bri3provided by MGI
    Official Full Name
    brain protein I3provided by MGI
    Primary source
    MGI:MGI:1933174
    See related
    Ensembl:ENSMUSG00000047843 AllianceGenome:MGI:1933174
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    I3
    Summary
    Predicted to enable identical protein binding activity. Predicted to be located in lysosome and membrane. Predicted to be integral component of membrane. Is expressed in pituitary gland. Orthologous to human BRI3 (brain protein I3). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in stomach adult (RPKM 96.2), adrenal adult (RPKM 87.7) and 27 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Bri3 in Genome Data Viewer
    Location:
    5; 5 G2
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (144181247..144383567)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (144244437..144264573)

    Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene basic helix-loop-helix family, member a15 Neighboring gene tectonin beta-propeller repeat containing 1 Neighboring gene RIKEN cDNA 2900089D17 gene Neighboring gene BAI1-associated protein 2-like 1 Neighboring gene predicted gene 15708 Neighboring gene Dmrt1 interacting ncRNA Neighboring gene predicted gene, 33552 Neighboring gene predicted gene, 33714 Neighboring gene predicted gene, 33765

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 
    • Endonuclease-mediated (1) 

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in lysosome IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001163709.1NP_001157181.1  brain protein I3 isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (2) has a distinct N-terminus and is shorter than isoform 1.
      Source sequence(s)
      AC139636, AK049027, AK080467, BE991935
      Consensus CDS
      CCDS51694.1
      UniProtKB/TrEMBL
      E9PUB2, Q8C4X5, Q8C7X8
      Related
      ENSMUSP00000106323.2, ENSMUST00000110695.8
      Conserved Domains (1) summary
      pfam10164
      Location:40120
      DUF2367; Uncharacterized conserved protein (DUF2367)
    2. NM_018772.4NP_061242.3  brain protein I3 isoform 1

      See identical proteins and their annotated locations for NP_061242.3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      AC139636, AK049027, AK080467, BE991935
      Consensus CDS
      CCDS19848.1
      UniProtKB/Swiss-Prot
      P28662, Q9Z1S1
      UniProtKB/TrEMBL
      A0A6P5PQI3, Q8C4X5, Q8C7X8
      Related
      ENSMUSP00000057263.7, ENSMUST00000056578.7
      Conserved Domains (1) summary
      pfam10164
      Location:29124
      DUF2367; Uncharacterized conserved protein (DUF2367)

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000071.7 Reference GRCm39 C57BL/6J

      Range
      144181247..144383567
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036165318.1XP_036021211.1  brain protein I3 isoform X1

      Conserved Domains (1) summary
      pfam10164
      Location:2982
      DUF2367; Uncharacterized conserved protein (DUF2367)

    RNA

    1. XR_004942543.1 RNA Sequence

      Related
      ENSMUST00000155491.8