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    Ap3m1 adaptor-related protein complex 3, mu 1 subunit [ Mus musculus (house mouse) ]

    Gene ID: 55946, updated on 30-Aug-2022

    Summary

    Official Symbol
    Ap3m1provided by MGI
    Official Full Name
    adaptor-related protein complex 3, mu 1 subunitprovided by MGI
    Primary source
    MGI:MGI:1929212
    See related
    Ensembl:ENSMUSG00000021824 AllianceGenome:MGI:1929212
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1200013D09Rik
    Summary
    Predicted to enable small GTPase binding activity. Involved in anterograde synaptic vesicle transport. Predicted to be located in Golgi apparatus and membrane. Predicted to be part of clathrin adaptor complex. Predicted to be active in cytoplasmic vesicle. Orthologous to human AP3M1 (adaptor related protein complex 3 subunit mu 1). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in placenta adult (RPKM 16.1), CNS E11.5 (RPKM 13.4) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Ap3m1 in Genome Data Viewer
    Location:
    14 A3; 14 11.58 cM
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (21083810..21102603, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (21033106..21052553, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 14 NC_000080.5 (21852964..21871664, complement)

    Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene vinculin Neighboring gene predicted gene, 52168 Neighboring gene uncharacterized protein C3orf14 homolog pseudogene Neighboring gene adenosine kinase Neighboring gene VISTA enhancer mm1738 Neighboring gene predicted gene, 30363

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 
    • Endonuclease-mediated (2) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables small GTPase binding ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    part_of AP-3 adaptor complex IC
    Inferred by Curator
    more info
    PubMed 
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
     
    part_of clathrin adaptor complex IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in cytoplasmic vesicle IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in early endosome IC
    Inferred by Curator
    more info
    PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    AP-3 complex subunit mu-1
    Names
    AP-3 adapter complex mu3A subunit
    AP-3 adaptor complex mu3A subunit
    adapter-related protein complex 3 mu-1 subunit
    adapter-related protein complex 3 subunit mu-1
    adaptor-related protein complex 3 subunit mu-1
    adaptor-related protein complex AP-3, mu 1 subunit
    clathrin adaptor protein mu3A
    mu-adaptin 3A
    mu3A-adaptin

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_018829.4NP_061299.3  AP-3 complex subunit mu-1

      See identical proteins and their annotated locations for NP_061299.3

      Status: VALIDATED

      Source sequence(s)
      AC163681, BC090983, BY774570, CD551381
      Consensus CDS
      CCDS26861.1
      UniProtKB/Swiss-Prot
      Q5BKQ6, Q9JKC8
      UniProtKB/TrEMBL
      A0A6P7QIB2, A0A8C6GM57
      Related
      ENSMUSP00000117346.2, ENSMUST00000154460.8
      Conserved Domains (2) summary
      cd09260
      Location:165418
      AP-3_Mu3A_Cterm; C-terminal domain of medium Mu3A subunit in ubiquitously expressed adaptor protein (AP) complex AP-3
      cd14837
      Location:3141
      AP3_Mu_N; AP-3 complex subunit mu N-terminal domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000080.7 Reference GRCm39 C57BL/6J

      Range
      21083810..21102603 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006519292.3XP_006519355.1  AP-3 complex subunit mu-1 isoform X1

      See identical proteins and their annotated locations for XP_006519355.1

      UniProtKB/Swiss-Prot
      Q5BKQ6, Q9JKC8
      UniProtKB/TrEMBL
      A0A6P7QIB2, A0A8C6GM57
      Conserved Domains (2) summary
      cd09260
      Location:165418
      AP-3_Mu3A_Cterm; C-terminal domain of medium Mu3A subunit in ubiquitously expressed adaptor protein (AP) complex AP-3
      cd14837
      Location:3141
      AP3_Mu_N; AP-3 complex subunit mu N-terminal domain
    2. XM_006519293.3XP_006519356.1  AP-3 complex subunit mu-1 isoform X1

      See identical proteins and their annotated locations for XP_006519356.1

      UniProtKB/Swiss-Prot
      Q5BKQ6, Q9JKC8
      UniProtKB/TrEMBL
      A0A6P7QIB2, A0A8C6GM57
      Related
      ENSMUSP00000022371.4, ENSMUST00000022371.10
      Conserved Domains (2) summary
      cd09260
      Location:165418
      AP-3_Mu3A_Cterm; C-terminal domain of medium Mu3A subunit in ubiquitously expressed adaptor protein (AP) complex AP-3
      cd14837
      Location:3141
      AP3_Mu_N; AP-3 complex subunit mu N-terminal domain

    RNA

    1. XR_003950866.2 RNA Sequence