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    Ap3m1 adaptor-related protein complex 3, mu 1 subunit [ Mus musculus (house mouse) ]

    Gene ID: 55946, updated on 31-Jan-2019

    Summary

    Official Symbol
    Ap3m1provided by MGI
    Official Full Name
    adaptor-related protein complex 3, mu 1 subunitprovided by MGI
    Primary source
    MGI:MGI:1929212
    See related
    Ensembl:ENSMUSG00000021824
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    C78982; R75378; 1200013D09Rik
    Expression
    Ubiquitous expression in placenta adult (RPKM 16.1), CNS E11.5 (RPKM 13.4) and 28 other tissues See more
    Orthologs

    Genomic context

    See Ap3m1 in Genome Data Viewer
    Location:
    14 A3; 14 11.58 cM
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 14 NC_000080.6 (21033742..21052535, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 14 NC_000080.5 (21852964..21871664, complement)

    Chromosome 14 - NC_000080.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 30212 Neighboring gene vinculin Neighboring gene predicted gene, 30274 Neighboring gene adenosine kinase Neighboring gene predicted gene, 30363

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    Pathways from BioSystems

    • Lysosome, organism-specific biosystem (from KEGG)
      Lysosome, organism-specific biosystemLysosomes are membrane-delimited organelles in animal cells serving as the cell's main digestive compartment to which all sorts of macromolecules are delivered for degradation. They contain more than...
    • Lysosome, conserved biosystem (from KEGG)
      Lysosome, conserved biosystemLysosomes are membrane-delimited organelles in animal cells serving as the cell's main digestive compartment to which all sorts of macromolecules are delivered for degradation. They contain more than...

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    Rab GTPase binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    anterograde axonal transport IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    anterograde synaptic vesicle transport IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    intracellular protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    vesicle-mediated transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
     
    axon IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    axon cytoplasm IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    cell IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    clathrin adaptor complex IEA
    Inferred from Electronic Annotation
    more info
     
    cytoplasmic vesicle IEA
    Inferred from Electronic Annotation
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    synapse IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 

    General protein information

    Preferred Names
    AP-3 complex subunit mu-1
    Names
    AP-3 adapter complex mu3A subunit
    AP-3 adaptor complex mu3A subunit
    adapter-related protein complex 3 mu-1 subunit
    adapter-related protein complex 3 subunit mu-1
    adaptor-related protein complex 3 subunit mu-1
    adaptor-related protein complex AP-3, mu 1 subunit
    clathrin adaptor protein mu3A
    mu-adaptin 3A
    mu3A-adaptin

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_018829.4NP_061299.3  AP-3 complex subunit mu-1

      See identical proteins and their annotated locations for NP_061299.3

      Status: VALIDATED

      Source sequence(s)
      AC163681, BC090983, BY774570, CD551381
      Consensus CDS
      CCDS26861.1
      UniProtKB/Swiss-Prot
      Q9JKC8
      Related
      ENSMUSP00000117346.1, ENSMUST00000154460.7
      Conserved Domains (2) summary
      cd09260
      Location:165418
      AP-3_Mu3A_Cterm; C-terminal domain of medium Mu3A subunit in ubiquitously expressed adaptor protein (AP) complex AP-3
      cl02092
      Location:1144
      Clat_adaptor_s; Clathrin adaptor complex small chain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000080.6 Reference GRCm38.p4 C57BL/6J

      Range
      21033742..21052535 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006519292.1XP_006519355.1  AP-3 complex subunit mu-1 isoform X1

      See identical proteins and their annotated locations for XP_006519355.1

      UniProtKB/Swiss-Prot
      Q9JKC8
      Conserved Domains (2) summary
      cd09260
      Location:165418
      AP-3_Mu3A_Cterm; C-terminal domain of medium Mu3A subunit in ubiquitously expressed adaptor protein (AP) complex AP-3
      cl02092
      Location:1144
      Clat_adaptor_s; Clathrin adaptor complex small chain
    2. XM_006519293.1XP_006519356.1  AP-3 complex subunit mu-1 isoform X1

      See identical proteins and their annotated locations for XP_006519356.1

      UniProtKB/Swiss-Prot
      Q9JKC8
      Conserved Domains (2) summary
      cd09260
      Location:165418
      AP-3_Mu3A_Cterm; C-terminal domain of medium Mu3A subunit in ubiquitously expressed adaptor protein (AP) complex AP-3
      cl02092
      Location:1144
      Clat_adaptor_s; Clathrin adaptor complex small chain
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