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    CEP55 centrosomal protein 55 [ Homo sapiens (human) ]

    Gene ID: 55165, updated on 8-Jul-2021

    Summary

    Official Symbol
    CEP55provided by HGNC
    Official Full Name
    centrosomal protein 55provided by HGNC
    Primary source
    HGNC:HGNC:1161
    See related
    Ensembl:ENSG00000138180 MIM:610000
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    CT111; MARCH; URCC6; C10orf3
    Expression
    Broad expression in testis (RPKM 13.8), lymph node (RPKM 8.3) and 14 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See CEP55 in Genome Data Viewer
    Location:
    10q23.33
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    109.20210514 current GRCh38.p13 (GCF_000001405.39) 10 NC_000010.11 (93496612..93529094)
    105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (95256369..95288849)

    Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene ribosomal protein L17 pseudogene 34 Neighboring gene myoferlin Neighboring gene Sharpr-MPRA regulatory region 10561 Neighboring gene RNA, 5S ribosomal pseudogene 323 Neighboring gene uncharacterized LOC105378436 Neighboring gene free fatty acid receptor 4

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • FLJ10540

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables identical protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in Flemming body IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in centriolar satellite IDA
    Inferred from Direct Assay
    more info
     
    located_in centriole IEA
    Inferred from Electronic Annotation
    more info
     
    located_in centrosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cleavage furrow IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in intercellular bridge IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane HDA PubMed 
    is_active_in midbody IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in midbody IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
     

    General protein information

    Preferred Names
    centrosomal protein of 55 kDa
    Names
    cancer/testis antigen 111
    centrosomal protein 55kDa
    up-regulated in colon cancer 6

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001127182.2NP_001120654.2  centrosomal protein of 55 kDa

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) results from use of an alternate splice donor site for exon 1.
      Source sequence(s)
      AL356214
      Consensus CDS
      CCDS7428.1
      Conserved Domains (1) summary
      COG1196
      Location:21405
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    2. NM_018131.5NP_060601.4  centrosomal protein of 55 kDa

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) results from use of an alternate splice donor site for exon 1.
      Source sequence(s)
      AL356214
      Consensus CDS
      CCDS7428.1
      Related
      ENSP00000360540.3, ENST00000371485.8
      Conserved Domains (1) summary
      COG1196
      Location:21405
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

    RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p13 Primary Assembly

    Genomic

    1. NC_000010.11 Reference GRCh38.p13 Primary Assembly

      Range
      93496612..93529094
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011539919.1XP_011538221.1  centrosomal protein of 55 kDa isoform X1

      See identical proteins and their annotated locations for XP_011538221.1

      Conserved Domains (1) summary
      pfam12180
      Location:235
      EABR; TSG101 and ALIX binding domain of CEP55
    2. XM_011539918.1XP_011538220.1  centrosomal protein of 55 kDa isoform X1

      See identical proteins and their annotated locations for XP_011538220.1

      Conserved Domains (1) summary
      pfam12180
      Location:235
      EABR; TSG101 and ALIX binding domain of CEP55
    3. XM_017016373.1XP_016871862.1  centrosomal protein of 55 kDa isoform X1

      Conserved Domains (1) summary
      pfam12180
      Location:235
      EABR; TSG101 and ALIX binding domain of CEP55
    4. XM_017016372.1XP_016871861.1  centrosomal protein of 55 kDa isoform X1

      Conserved Domains (1) summary
      pfam12180
      Location:235
      EABR; TSG101 and ALIX binding domain of CEP55
    5. XM_011539920.2XP_011538222.1  centrosomal protein of 55 kDa isoform X1

      See identical proteins and their annotated locations for XP_011538222.1

      Conserved Domains (1) summary
      pfam12180
      Location:235
      EABR; TSG101 and ALIX binding domain of CEP55
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