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    ZCWPW1 zinc finger CW-type and PWWP domain containing 1 [ Homo sapiens (human) ]

    Gene ID: 55063, updated on 17-Jun-2024

    Summary

    Official Symbol
    ZCWPW1provided by HGNC
    Official Full Name
    zinc finger CW-type and PWWP domain containing 1provided by HGNC
    Primary source
    HGNC:HGNC:23486
    See related
    Ensembl:ENSG00000078487 MIM:618900; AllianceGenome:HGNC:23486
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    ZCW1
    Summary
    Enables methyl-CpG binding activity and methylated histone binding activity. Predicted to be involved in meiosis I; positive regulation of DNA metabolic process; and spermatogenesis. Predicted to act upstream of or within homologous chromosome pairing at meiosis. Predicted to be located in XY body. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Broad expression in testis (RPKM 25.2), thyroid (RPKM 2.9) and 16 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See ZCWPW1 in Genome Data Viewer
    Location:
    7q22.1
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 7 NC_000007.14 (100400872..100428703, complement)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 7 NC_060931.1 (101640949..101668781, complement)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (99998495..100026326, complement)

    Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene STAG3L5P-PVRIG2P-PILRB readthrough Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26356 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26357 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26358 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26359 Neighboring gene paired immunoglobin like type 2 receptor beta Neighboring gene OCT4-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:99968027-99968778 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26360 Neighboring gene paired immunoglobin like type 2 receptor alpha Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26361 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:99995395-99995894 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26362 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18431 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26363 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26364 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18432 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26365 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18433 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:100034207-100034710 Neighboring gene PPP1R35 antisense RNA 1 Neighboring gene methylphosphate capping enzyme Neighboring gene protein phosphatase 1 regulatory subunit 35

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Phenotypes

    EBI GWAS Catalog

    Description
    An atlas of genetic influences on human blood metabolites.
    EBI GWAS Catalog
    Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease.
    EBI GWAS Catalog

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • FLJ10057, DKFZp434N0510

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables methyl-CpG binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables methylated histone binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables methylated histone binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables methylated histone binding IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    enables methylated histone binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in cell differentiation IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within homologous chromosome pairing at meiosis ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in homologous chromosome pairing at meiosis ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in meiosis I ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in positive regulation of DNA recombination ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in positive regulation of double-strand break repair ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in spermatogenesis ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    located_in chromosome IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    zinc finger CW-type PWWP domain protein 1
    Names
    zinc finger CW-type and PWWP domain 1
    zinc finger, CW-type with PWWP domain 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001258008.3NP_001244937.1  zinc finger CW-type PWWP domain protein 1 isoform 2

      See identical proteins and their annotated locations for NP_001244937.1

      Status: VALIDATED

      Source sequence(s)
      AC005071, AC092849
      Consensus CDS
      CCDS59067.1
      UniProtKB/Swiss-Prot
      Q9H0M4
      Related
      ENSP00000354210.4, ENST00000360951.8
      Conserved Domains (2) summary
      pfam07496
      Location:256302
      zf-CW; CW-type Zinc Finger
      cl02554
      Location:314417
      PWWP; The PWWP domain, named for a conserved Pro-Trp-Trp-Pro motif, is a small domain consisting of 100-150 amino acids. The PWWP domain is found in numerous proteins that are involved in cell division, growth and differentiation. Most PWWP-domain proteins ...
    2. NM_001386008.1NP_001372937.1  zinc finger CW-type PWWP domain protein 1 isoform 14

      Status: VALIDATED

      Source sequence(s)
      AC005071, AC092849
      Conserved Domains (1) summary
      cl02554
      Location:85155
      PWWP; The PWWP domain, named for a conserved Pro-Trp-Trp-Pro motif, is a small domain consisting of 100-150 amino acids. The PWWP domain is found in numerous proteins that are involved in cell division, growth and differentiation. Most PWWP-domain proteins ...
    3. NM_001386009.1NP_001372938.1  zinc finger CW-type PWWP domain protein 1 isoform 10

      Status: VALIDATED

      Source sequence(s)
      AC005071, AC092849
      UniProtKB/TrEMBL
      A0A0S2Z5K5
      Conserved Domains (2) summary
      pfam07496
      Location:188234
      zf-CW; CW-type Zinc Finger
      cl02554
      Location:246349
      PWWP; The PWWP domain, named for a conserved Pro-Trp-Trp-Pro motif, is a small domain consisting of 100-150 amino acids. The PWWP domain is found in numerous proteins that are involved in cell division, growth and differentiation. Most PWWP-domain proteins ...
    4. NM_001386010.1NP_001372939.1  zinc finger CW-type PWWP domain protein 1 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC005071, AC092849
      Consensus CDS
      CCDS94155.1
      UniProtKB/TrEMBL
      A0A804HK41, B4DXS7
      Related
      ENSP00000507762.1, ENST00000684423.1
      Conserved Domains (2) summary
      cd05837
      Location:314417
      MSH6_like; The PWWP domain is present in MSH6, a mismatch repair protein homologous to bacterial MutS. The PWWP domain of histone-lysine N-methyltransferase, also known as Nuclear SET domain-containing protein 3, is also included. Mutations in MSH6 have been ...
      pfam07496
      Location:256302
      zf-CW; CW-type Zinc Finger
    5. NM_001386011.1NP_001372940.1  zinc finger CW-type PWWP domain protein 1 isoform 12

      Status: VALIDATED

      Source sequence(s)
      AC005071, AC092849
      Conserved Domains (2) summary
      pfam07496
      Location:125171
      zf-CW; CW-type Zinc Finger
      cl02554
      Location:183286
      PWWP; The PWWP domain, named for a conserved Pro-Trp-Trp-Pro motif, is a small domain consisting of 100-150 amino acids. The PWWP domain is found in numerous proteins that are involved in cell division, growth and differentiation. Most PWWP-domain proteins ...
    6. NM_001386012.1NP_001372941.1  zinc finger CW-type PWWP domain protein 1 isoform 7

      Status: VALIDATED

      Source sequence(s)
      AC005071, AC092849
      UniProtKB/TrEMBL
      B4DXS7
      Conserved Domains (2) summary
      cd05837
      Location:183286
      MSH6_like; The PWWP domain is present in MSH6, a mismatch repair protein homologous to bacterial MutS. The PWWP domain of histone-lysine N-methyltransferase, also known as Nuclear SET domain-containing protein 3, is also included. Mutations in MSH6 have been ...
      pfam07496
      Location:125171
      zf-CW; CW-type Zinc Finger
    7. NM_001386013.1NP_001372942.1  zinc finger CW-type PWWP domain protein 1 isoform 6

      Status: VALIDATED

      Source sequence(s)
      AC005071, AC092849
      Conserved Domains (2) summary
      pfam07496
      Location:256303
      zf-CW; CW-type Zinc Finger
      cl02554
      Location:315418
      PWWP; The PWWP domain, named for a conserved Pro-Trp-Trp-Pro motif, is a small domain consisting of 100-150 amino acids. The PWWP domain is found in numerous proteins that are involved in cell division, growth and differentiation. Most PWWP-domain proteins ...
    8. NM_001386015.1NP_001372944.1  zinc finger CW-type PWWP domain protein 1 isoform 11

      Status: VALIDATED

      Source sequence(s)
      AC005071, AC092849
      UniProtKB/TrEMBL
      A0A0S2Z5J5
      Conserved Domains (2) summary
      cd05837
      Location:113216
      MSH6_like; The PWWP domain is present in MSH6, a mismatch repair protein homologous to bacterial MutS. The PWWP domain of histone-lysine N-methyltransferase, also known as Nuclear SET domain-containing protein 3, is also included. Mutations in MSH6 have been ...
      pfam07496
      Location:55101
      zf-CW; CW-type Zinc Finger
    9. NM_001386016.1NP_001372945.1  zinc finger CW-type PWWP domain protein 1 isoform 4

      Status: VALIDATED

      Source sequence(s)
      AC005071, AC092849
      UniProtKB/TrEMBL
      B4DXS7
      Conserved Domains (2) summary
      cd05837
      Location:314417
      MSH6_like; The PWWP domain is present in MSH6, a mismatch repair protein homologous to bacterial MutS. The PWWP domain of histone-lysine N-methyltransferase, also known as Nuclear SET domain-containing protein 3, is also included. Mutations in MSH6 have been ...
      pfam07496
      Location:256302
      zf-CW; CW-type Zinc Finger
    10. NM_001386017.1NP_001372946.1  zinc finger CW-type PWWP domain protein 1 isoform 5

      Status: VALIDATED

      Source sequence(s)
      AC005071, AC092849
      UniProtKB/TrEMBL
      B4DXS7
      Conserved Domains (2) summary
      cd05837
      Location:315418
      MSH6_like; The PWWP domain is present in MSH6, a mismatch repair protein homologous to bacterial MutS. The PWWP domain of histone-lysine N-methyltransferase, also known as Nuclear SET domain-containing protein 3, is also included. Mutations in MSH6 have been ...
      pfam07496
      Location:256303
      zf-CW; CW-type Zinc Finger
    11. NM_001386018.1NP_001372947.1  zinc finger CW-type PWWP domain protein 1 isoform 6

      Status: VALIDATED

      Source sequence(s)
      AC005071, AC092849
      Conserved Domains (2) summary
      pfam07496
      Location:256303
      zf-CW; CW-type Zinc Finger
      cl02554
      Location:315418
      PWWP; The PWWP domain, named for a conserved Pro-Trp-Trp-Pro motif, is a small domain consisting of 100-150 amino acids. The PWWP domain is found in numerous proteins that are involved in cell division, growth and differentiation. Most PWWP-domain proteins ...
    12. NM_001386019.1NP_001372948.1  zinc finger CW-type PWWP domain protein 1 isoform 10

      Status: VALIDATED

      Source sequence(s)
      AC005071, AC092849
      UniProtKB/TrEMBL
      A0A0S2Z5K5
      Conserved Domains (2) summary
      pfam07496
      Location:188234
      zf-CW; CW-type Zinc Finger
      cl02554
      Location:246349
      PWWP; The PWWP domain, named for a conserved Pro-Trp-Trp-Pro motif, is a small domain consisting of 100-150 amino acids. The PWWP domain is found in numerous proteins that are involved in cell division, growth and differentiation. Most PWWP-domain proteins ...
    13. NM_001386020.1NP_001372949.1  zinc finger CW-type PWWP domain protein 1 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC005071, AC092849
      Consensus CDS
      CCDS59067.1
      Conserved Domains (2) summary
      pfam07496
      Location:256302
      zf-CW; CW-type Zinc Finger
      cl02554
      Location:314417
      PWWP; The PWWP domain, named for a conserved Pro-Trp-Trp-Pro motif, is a small domain consisting of 100-150 amino acids. The PWWP domain is found in numerous proteins that are involved in cell division, growth and differentiation. Most PWWP-domain proteins ...
    14. NM_001386021.1NP_001372950.1  zinc finger CW-type PWWP domain protein 1 isoform 13

      Status: VALIDATED

      Source sequence(s)
      AC005071, AC092849
      Conserved Domains (2) summary
      pfam07496
      Location:55102
      zf-CW; CW-type Zinc Finger
      cl02554
      Location:114217
      PWWP; The PWWP domain, named for a conserved Pro-Trp-Trp-Pro motif, is a small domain consisting of 100-150 amino acids. The PWWP domain is found in numerous proteins that are involved in cell division, growth and differentiation. Most PWWP-domain proteins ...
    15. NM_001386022.1NP_001372951.1  zinc finger CW-type PWWP domain protein 1 isoform 8

      Status: VALIDATED

      Source sequence(s)
      AC005071, AC092849
      Conserved Domains (2) summary
      pfam07496
      Location:256302
      zf-CW; CW-type Zinc Finger
      cl02554
      Location:314385
      PWWP; The PWWP domain, named for a conserved Pro-Trp-Trp-Pro motif, is a small domain consisting of 100-150 amino acids. The PWWP domain is found in numerous proteins that are involved in cell division, growth and differentiation. Most PWWP-domain proteins ...
    16. NM_001386023.1NP_001372952.1  zinc finger CW-type PWWP domain protein 1 isoform 9

      Status: VALIDATED

      Source sequence(s)
      AC005071, AC092849
      UniProtKB/TrEMBL
      A0A0S2Z5E1
      Conserved Domains (2) summary
      pfam07496
      Location:188235
      zf-CW; CW-type Zinc Finger
      cl02554
      Location:247350
      PWWP; The PWWP domain, named for a conserved Pro-Trp-Trp-Pro motif, is a small domain consisting of 100-150 amino acids. The PWWP domain is found in numerous proteins that are involved in cell division, growth and differentiation. Most PWWP-domain proteins ...
    17. NM_001388066.1NP_001374995.1  zinc finger CW-type PWWP domain protein 1 isoform 15

      Status: VALIDATED

      Source sequence(s)
      AC005071, AC092849
    18. NM_017984.6NP_060454.3  zinc finger CW-type PWWP domain protein 1 isoform 1

      See identical proteins and their annotated locations for NP_060454.3

      Status: VALIDATED

      Source sequence(s)
      AC005071, AC092849
      Consensus CDS
      CCDS43623.1
      UniProtKB/Swiss-Prot
      A8MVF5, B4DUQ2, Q8NA98, Q9BUD0, Q9H0M4, Q9NWF7
      UniProtKB/TrEMBL
      B4DXS7
      Related
      ENSP00000381109.2, ENST00000398027.6
      Conserved Domains (2) summary
      cd05837
      Location:313416
      MSH6_like; The PWWP domain is present in MSH6, a mismatch repair protein homologous to bacterial MutS. The PWWP domain of histone-lysine N-methyltransferase, also known as Nuclear SET domain-containing protein 3, is also included. Mutations in MSH6 have been ...
      pfam07496
      Location:256301
      zf-CW; CW-type Zinc Finger

    RNA

    1. NR_169828.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC005071, AC092849
    2. NR_169829.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC005071, AC092849
    3. NR_169830.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC005071, AC092849
    4. NR_169831.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC005071, AC092849
    5. NR_169832.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC005071, AC092849
    6. NR_169834.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC005071, AC092849
    7. NR_169835.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC005071, AC092849
    8. NR_169836.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC005071, AC092849
    9. NR_169837.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC005071, AC092849
    10. NR_169838.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC005071, AC092849
    11. NR_169839.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC005071, AC092849

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000007.14 Reference GRCh38.p14 Primary Assembly

      Range
      100400872..100428703 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_047420554.1XP_047276510.1  zinc finger CW-type PWWP domain protein 1 isoform X10

    2. XM_006716038.5XP_006716101.1  zinc finger CW-type PWWP domain protein 1 isoform X3

      UniProtKB/TrEMBL
      B4DXS7
      Conserved Domains (2) summary
      cd05837
      Location:314417
      MSH6_like; The PWWP domain is present in MSH6, a mismatch repair protein homologous to bacterial MutS. The PWWP domain of histone-lysine N-methyltransferase, also known as Nuclear SET domain-containing protein 3, is also included. Mutations in MSH6 have been ...
      pfam07496
      Location:256302
      zf-CW; CW-type Zinc Finger
    3. XM_017012379.3XP_016867868.1  zinc finger CW-type PWWP domain protein 1 isoform X8

      Conserved Domains (2) summary
      pfam07496
      Location:256302
      zf-CW; CW-type Zinc Finger
      cl02554
      Location:314385
      PWWP; The PWWP domain, named for a conserved Pro-Trp-Trp-Pro motif, is a small domain consisting of 100-150 amino acids. The PWWP domain is found in numerous proteins that are involved in cell division, growth and differentiation. Most PWWP-domain proteins ...
    4. XM_024446815.2XP_024302583.1  zinc finger CW-type PWWP domain protein 1 isoform X6

      UniProtKB/TrEMBL
      B4DXS7
      Conserved Domains (2) summary
      pfam07496
      Location:257302
      zf-CW; CW-type Zinc Finger
      cl02554
      Location:314385
      PWWP; The PWWP domain, named for a conserved Pro-Trp-Trp-Pro motif, is a small domain consisting of 100-150 amino acids. The PWWP domain is found in numerous proteins that are involved in cell division, growth and differentiation. Most PWWP-domain proteins ...
    5. XM_005250480.4XP_005250537.1  zinc finger CW-type PWWP domain protein 1 isoform X7

      Conserved Domains (2) summary
      pfam07496
      Location:257303
      zf-CW; CW-type Zinc Finger
      cl02554
      Location:315386
      PWWP; The PWWP domain, named for a conserved Pro-Trp-Trp-Pro motif, is a small domain consisting of 100-150 amino acids. The PWWP domain is found in numerous proteins that are involved in cell division, growth and differentiation. Most PWWP-domain proteins ...
    6. XM_006716040.5XP_006716103.1  zinc finger CW-type PWWP domain protein 1 isoform X5

      UniProtKB/TrEMBL
      B4DXS7
      Conserved Domains (2) summary
      pfam07496
      Location:257303
      zf-CW; CW-type Zinc Finger
      cl02554
      Location:315386
      PWWP; The PWWP domain, named for a conserved Pro-Trp-Trp-Pro motif, is a small domain consisting of 100-150 amino acids. The PWWP domain is found in numerous proteins that are involved in cell division, growth and differentiation. Most PWWP-domain proteins ...
    7. XM_006716035.5XP_006716098.1  zinc finger CW-type PWWP domain protein 1 isoform X1

      See identical proteins and their annotated locations for XP_006716098.1

      UniProtKB/TrEMBL
      B4DXS7
      Conserved Domains (2) summary
      cd05837
      Location:315418
      MSH6_like; The PWWP domain is present in MSH6, a mismatch repair protein homologous to bacterial MutS. The PWWP domain of histone-lysine N-methyltransferase, also known as Nuclear SET domain-containing protein 3, is also included. Mutations in MSH6 have been ...
      pfam07496
      Location:257303
      zf-CW; CW-type Zinc Finger
    8. XM_047420552.1XP_047276508.1  zinc finger CW-type PWWP domain protein 1 isoform X4

      UniProtKB/Swiss-Prot
      A8MVF5, B4DUQ2, Q8NA98, Q9BUD0, Q9H0M4, Q9NWF7
      UniProtKB/TrEMBL
      B4DXS7
    9. XM_047420553.1XP_047276509.1  zinc finger CW-type PWWP domain protein 1 isoform X6

      UniProtKB/TrEMBL
      B4DXS7
    10. XM_047420551.1XP_047276507.1  zinc finger CW-type PWWP domain protein 1 isoform X2

      UniProtKB/TrEMBL
      A0A804HK41, B4DXS7
    11. XM_006716036.4XP_006716099.1  zinc finger CW-type PWWP domain protein 1 isoform X1

      See identical proteins and their annotated locations for XP_006716099.1

      UniProtKB/TrEMBL
      B4DXS7
      Conserved Domains (2) summary
      cd05837
      Location:315418
      MSH6_like; The PWWP domain is present in MSH6, a mismatch repair protein homologous to bacterial MutS. The PWWP domain of histone-lysine N-methyltransferase, also known as Nuclear SET domain-containing protein 3, is also included. Mutations in MSH6 have been ...
      pfam07496
      Location:257303
      zf-CW; CW-type Zinc Finger
    12. XM_024446817.2XP_024302585.1  zinc finger CW-type PWWP domain protein 1 isoform X9

      Conserved Domains (2) summary
      pfam07496
      Location:257303
      zf-CW; CW-type Zinc Finger
      cl02554
      Location:315331
      PWWP; The PWWP domain, named for a conserved Pro-Trp-Trp-Pro motif, is a small domain consisting of 100-150 amino acids. The PWWP domain is found in numerous proteins that are involved in cell division, growth and differentiation. Most PWWP-domain proteins ...

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060931.1 Alternate T2T-CHM13v2.0

      Range
      101640949..101668781 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054358551.1XP_054214526.1  zinc finger CW-type PWWP domain protein 1 isoform X10

    2. XM_054358543.1XP_054214518.1  zinc finger CW-type PWWP domain protein 1 isoform X3

      UniProtKB/TrEMBL
      B4DXS7
    3. XM_054358549.1XP_054214524.1  zinc finger CW-type PWWP domain protein 1 isoform X8

    4. XM_054358547.1XP_054214522.1  zinc finger CW-type PWWP domain protein 1 isoform X6

      UniProtKB/TrEMBL
      B4DXS7
    5. XM_054358548.1XP_054214523.1  zinc finger CW-type PWWP domain protein 1 isoform X7

    6. XM_054358545.1XP_054214520.1  zinc finger CW-type PWWP domain protein 1 isoform X5

      UniProtKB/TrEMBL
      B4DXS7
    7. XM_054358541.1XP_054214516.1  zinc finger CW-type PWWP domain protein 1 isoform X1

      UniProtKB/TrEMBL
      B4DXS7
    8. XM_054358544.1XP_054214519.1  zinc finger CW-type PWWP domain protein 1 isoform X4

      UniProtKB/Swiss-Prot
      A8MVF5, B4DUQ2, Q8NA98, Q9BUD0, Q9H0M4, Q9NWF7
      UniProtKB/TrEMBL
      B4DXS7
    9. XM_054358546.1XP_054214521.1  zinc finger CW-type PWWP domain protein 1 isoform X6

      UniProtKB/TrEMBL
      B4DXS7
    10. XM_054358542.1XP_054214517.1  zinc finger CW-type PWWP domain protein 1 isoform X2

      UniProtKB/TrEMBL
      A0A804HK41, B4DXS7
    11. XM_054358540.1XP_054214515.1  zinc finger CW-type PWWP domain protein 1 isoform X1

      UniProtKB/TrEMBL
      B4DXS7
    12. XM_054358550.1XP_054214525.1  zinc finger CW-type PWWP domain protein 1 isoform X9