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    SLC35F6 solute carrier family 35 member F6 [ Homo sapiens (human) ]

    Gene ID: 54978, updated on 5-Mar-2024

    Summary

    Official Symbol
    SLC35F6provided by HGNC
    Official Full Name
    solute carrier family 35 member F6provided by HGNC
    Primary source
    HGNC:HGNC:26055
    See related
    Ensembl:ENSG00000213699 MIM:619667; AllianceGenome:HGNC:26055
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    ANT2BP; TANGO9; C2orf18
    Summary
    Predicted to enable transmembrane transporter activity. Involved in negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway and positive regulation of cell population proliferation. Located in several cellular components, including lysosomal membrane; mitochondrion; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in thyroid (RPKM 11.5), skin (RPKM 10.8) and 25 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See SLC35F6 in Genome Data Viewer
    Location:
    2p23.3
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 2 NC_000002.12 (26764284..26781231)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 2 NC_060926.1 (26805872..26822820)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (26987152..27004099)

    Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene ribosomal protein L37 pseudogene 11 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:26919925-26920426 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:26929035-26929932 Neighboring gene potassium two pore domain channel subfamily K member 3 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:26932169-26933090 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:26933091-26934010 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr2:26946480-26947679 Neighboring gene H3K27ac hESC enhancer GRCh37_chr2:26960802-26961302 Neighboring gene H3K27ac hESC enhancer GRCh37_chr2:26961303-26961803 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:26965319-26965824 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:26972913-26973660 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:26975905-26976652 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:26976653-26977400 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:26977401-26978148 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:26981141-26981888 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:26981889-26982634 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15476 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11276 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:27007325-27008094 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15477 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11277 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15478 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15479 Neighboring gene MPRA-validated peak3629 silencer Neighboring gene centromere protein A Neighboring gene CDKN2A interacting protein N-terminal like pseudogene 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Potential readthrough

    Included gene: CENPA

    Clone Names

    • FLJ20555

    General protein information

    Preferred Names
    solute carrier family 35 member F6
    Names
    ANT2-binding protein
    transmembrane protein C2orf18
    transport and golgi organization 9 homolog

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_017877.4NP_060347.2  solute carrier family 35 member F6 precursor

      See identical proteins and their annotated locations for NP_060347.2

      Status: VALIDATED

      Source sequence(s)
      AC011740, AY358820
      Consensus CDS
      CCDS1728.1
      UniProtKB/Swiss-Prot
      D6W543, Q53GK2, Q8N357, Q8NBX6, Q9NWX0
      Related
      ENSP00000345528.5, ENST00000344420.10
      Conserved Domains (1) summary
      pfam06027
      Location:95222
      SLC35F; Solute carrier family 35

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000002.12 Reference GRCh38.p14 Primary Assembly

      Range
      26764284..26781231
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060926.1 Alternate T2T-CHM13v2.0

      Range
      26805872..26822820
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)