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    Eif3i eukaryotic translation initiation factor 3, subunit I [ Mus musculus (house mouse) ]

    Gene ID: 54709, updated on 23-Jun-2021

    Summary

    Official Symbol
    Eif3iprovided by MGI
    Official Full Name
    eukaryotic translation initiation factor 3, subunit Iprovided by MGI
    Primary source
    MGI:MGI:1860763
    See related
    Ensembl:ENSMUSG00000028798
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    TRI; 36kD; Eif3; 36kDa; Trip1; Eif3s2; D4Ertd632; D4Ertd632e
    Expression
    Ubiquitous expression in genital fat pad adult (RPKM 152.6), liver E14.5 (RPKM 125.2) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Eif3i in Genome Data Viewer
    Location:
    4 D2.2; 4 63.26 cM
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (129485767..129494441, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (129591974..129600648, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 4 NC_000070.5 (129269218..129277892, complement)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene lymphocyte protein tyrosine kinase Neighboring gene microRNA 8119 Neighboring gene family with sequence similarity 167, member B Neighboring gene transmembrane protein 234 Neighboring gene doublecortin domain containing 2b Neighboring gene IQ motif containing C

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables enzyme binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    contributes_to translation initiation factor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    contributes_to translation initiation factor activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables translation initiation factor activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in cytoplasmic translational initiation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within translation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in translational initiation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in translational initiation ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    eukaryotic translation initiation factor 3 subunit I
    Names
    TGF-beta receptor binding protein
    TGF-beta receptor-interacting protein 1
    TRIP-1
    eukaryotic translation initiation factor 3, subunit 1
    eukaryotic translation initiation factor 3, subunit 2 (beta)
    eukaryotic translation initiation factor 3, subunit 2 (beta, 36kD)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_018799.2NP_061269.1  eukaryotic translation initiation factor 3 subunit I

      See identical proteins and their annotated locations for NP_061269.1

      Status: VALIDATED

      Source sequence(s)
      AK010781, BP769420, CJ079467
      Consensus CDS
      CCDS18698.1
      UniProtKB/Swiss-Prot
      Q9QZD9
      Related
      ENSMUSP00000099653.5, ENSMUST00000102593.11
      Conserved Domains (3) summary
      COG2319
      Location:6311
      WD40; WD40 repeat [General function prediction only]
      sd00039
      Location:1450
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:6311
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      129485767..129494441 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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