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    Sfmbt1 Scm-like with four mbt domains 1 [ Mus musculus (house mouse) ]

    Gene ID: 54650, updated on 23-Jun-2021

    Summary

    Official Symbol
    Sfmbt1provided by MGI
    Official Full Name
    Scm-like with four mbt domains 1provided by MGI
    Primary source
    MGI:MGI:1859609
    See related
    Ensembl:ENSMUSG00000006527
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    S; Smr; Sfmbt; AA536974; 4930442N21Rik; 9330180L21Rik
    Expression
    Broad expression in testis adult (RPKM 3.7), placenta adult (RPKM 2.4) and 24 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Sfmbt1 in Genome Data Viewer
    Location:
    14 B; 14 18.99 cM
    Exon count:
    28
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (30436806..30544678)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (30714849..30822721)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 14 NC_000080.5 (31528035..31635907)

    Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 53839 Neighboring gene RFT1 homolog Neighboring gene RIKEN cDNA 1700087M22 gene Neighboring gene transformer 2 beta homolog pseudogene Neighboring gene STIM activating enhancer Neighboring gene musculoskeletal, embryonic nuclear protein 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • DKFZp434L243

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables chromatin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables histone binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables histone binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables transcription corepressor activity IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    scm-like with four MBT domains protein 1
    Names
    Scm-related gene containing four mbt domains 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001166531.1NP_001160003.1  scm-like with four MBT domains protein 1

      See identical proteins and their annotated locations for NP_001160003.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) represents use of an alternate promoter and 5' UTR, compared to variant 1. Variants 1, 2, and 3 all encode the same protein.
      Source sequence(s)
      AB032165, AC154436, AK160573
      Consensus CDS
      CCDS26897.1
      UniProtKB/Swiss-Prot
      Q9JMD1
      UniProtKB/TrEMBL
      Q3TUT9
      Conserved Domains (3) summary
      cd09581
      Location:779863
      SAM_Scm-like-4MBT1,2; SAM domain of Scm-like-4MBT1,2 proteins of Polycomb group
      smart00561
      Location:23120
      MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
      pfam12140
      Location:499614
      SLED; SLED domain
    2. NM_001166532.1NP_001160004.1  scm-like with four MBT domains protein 1

      See identical proteins and their annotated locations for NP_001160004.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript. Variants 1, 2, and 3 all encode the same protein.
      Source sequence(s)
      AB032165, AC154436, BC036972
      Consensus CDS
      CCDS26897.1
      UniProtKB/Swiss-Prot
      Q9JMD1
      Related
      ENSMUSP00000056744.5, ENSMUST00000054230.12
      Conserved Domains (3) summary
      cd09581
      Location:779863
      SAM_Scm-like-4MBT1,2; SAM domain of Scm-like-4MBT1,2 proteins of Polycomb group
      smart00561
      Location:23120
      MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
      pfam12140
      Location:499614
      SLED; SLED domain
    3. NM_019460.2NP_062333.1  scm-like with four MBT domains protein 1

      See identical proteins and their annotated locations for NP_062333.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) represents use of an alternate promoter and 5' UTR, compared to variant 1. Variants 1, 2, and 3 all encode the same protein.
      Source sequence(s)
      AB032165, AC154436, BC066188, CJ077633
      Consensus CDS
      CCDS26897.1
      UniProtKB/Swiss-Prot
      Q9JMD1
      Related
      ENSMUSP00000107802.2, ENSMUST00000112184.10
      Conserved Domains (3) summary
      cd09581
      Location:779863
      SAM_Scm-like-4MBT1,2; SAM domain of Scm-like-4MBT1,2 proteins of Polycomb group
      smart00561
      Location:23120
      MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
      pfam12140
      Location:499614
      SLED; SLED domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000080.7 Reference GRCm39 C57BL/6J

      Range
      30436806..30544678
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006519289.5XP_006519352.1  scm-like with four MBT domains protein 1 isoform X1

      See identical proteins and their annotated locations for XP_006519352.1

      UniProtKB/Swiss-Prot
      Q9JMD1
      Conserved Domains (3) summary
      cd09581
      Location:779863
      SAM_Scm-like-4MBT1,2; SAM domain of Scm-like-4MBT1,2 proteins of Polycomb group
      smart00561
      Location:23120
      MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
      pfam12140
      Location:499614
      SLED; SLED domain
    2. XM_036158762.1XP_036014655.1  scm-like with four MBT domains protein 1 isoform X3

      Conserved Domains (3) summary
      cd09581
      Location:394478
      SAM_Scm-like-4MBT1,2; SAM domain of Scm-like-4MBT1,2 proteins of Polycomb group
      smart00561
      Location:166
      MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
      pfam12140
      Location:114229
      SLED; SLED domain
    3. XM_030247889.2XP_030103749.1  scm-like with four MBT domains protein 1 isoform X1

      Related
      ENSMUSP00000153962.2, ENSMUST00000227303.2
      Conserved Domains (3) summary
      cd09581
      Location:779863
      SAM_Scm-like-4MBT1,2; SAM domain of Scm-like-4MBT1,2 proteins of Polycomb group
      smart00561
      Location:23120
      MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
      pfam12140
      Location:499614
      SLED; SLED domain
    4. XM_011245120.3XP_011243422.1  scm-like with four MBT domains protein 1 isoform X1

      See identical proteins and their annotated locations for XP_011243422.1

      UniProtKB/Swiss-Prot
      Q9JMD1
      Conserved Domains (3) summary
      cd09581
      Location:779863
      SAM_Scm-like-4MBT1,2; SAM domain of Scm-like-4MBT1,2 proteins of Polycomb group
      smart00561
      Location:23120
      MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
      pfam12140
      Location:499614
      SLED; SLED domain
    5. XM_006519288.4XP_006519351.1  scm-like with four MBT domains protein 1 isoform X1

      See identical proteins and their annotated locations for XP_006519351.1

      UniProtKB/Swiss-Prot
      Q9JMD1
      Conserved Domains (3) summary
      cd09581
      Location:779863
      SAM_Scm-like-4MBT1,2; SAM domain of Scm-like-4MBT1,2 proteins of Polycomb group
      smart00561
      Location:23120
      MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
      pfam12140
      Location:499614
      SLED; SLED domain
    6. XM_006519287.4XP_006519350.1  scm-like with four MBT domains protein 1 isoform X1

      See identical proteins and their annotated locations for XP_006519350.1

      UniProtKB/Swiss-Prot
      Q9JMD1
      Related
      ENSMUSP00000153861.2, ENSMUST00000228006.2
      Conserved Domains (3) summary
      cd09581
      Location:779863
      SAM_Scm-like-4MBT1,2; SAM domain of Scm-like-4MBT1,2 proteins of Polycomb group
      smart00561
      Location:23120
      MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
      pfam12140
      Location:499614
      SLED; SLED domain
    7. XM_006519290.1XP_006519353.1  scm-like with four MBT domains protein 1 isoform X2

      Conserved Domains (3) summary
      cd09581
      Location:633717
      SAM_Scm-like-4MBT1,2; SAM domain of Scm-like-4MBT1,2 proteins of Polycomb group
      smart00561
      Location:212305
      MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
      pfam12140
      Location:353468
      SLED; SLED domain

    RNA

    1. XR_004938416.1 RNA Sequence

    2. XR_004938415.1 RNA Sequence

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_175254.2: Suppressed sequence

      Description
      NM_175254.2: This RefSeq was permanently suppressed because currently there is support for the transcript but not for the protein.
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