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    Gripap1 GRIP1 associated protein 1 [ Mus musculus (house mouse) ]

    Gene ID: 54645, updated on 31-Jan-2019

    Summary

    Official Symbol
    Gripap1provided by MGI
    Official Full Name
    GRIP1 associated protein 1provided by MGI
    Primary source
    MGI:MGI:1859616
    See related
    Ensembl:ENSMUSG00000031153
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Sfc10; GRASP-1; AI854681; DXImx47e; mKIAA1167
    Expression
    Ubiquitous expression in frontal lobe adult (RPKM 16.9), cerebellum adult (RPKM 16.4) and 28 other tissues See more
    Orthologs

    Genomic context

    See Gripap1 in Genome Data Viewer
    Location:
    X A1.1; X 3.51 cM
    Exon count:
    26
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) X NC_000086.7 (7789961..7820567)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) X NC_000086.6 (7367121..7397689)

    Chromosome X - NC_000086.7Genomic Context describing neighboring genes Neighboring gene SMT3 suppressor of mif two 3 homolog 2, pseudogene (S. cerevisiae) Neighboring gene transcription factor E3 Neighboring gene predicted gene, 39487 Neighboring gene microRNA 1198 Neighboring gene potassium voltage-gated channel, Shal-related family, member 1 Neighboring gene OTU domain containing 5

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    cell junction IEA
    Inferred from Electronic Annotation
    more info
     
    cell projection IEA
    Inferred from Electronic Annotation
    more info
     
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    endosome IEA
    Inferred from Electronic Annotation
    more info
     
    extrinsic component of postsynaptic early endosome membrane ISO
    Inferred from Sequence Orthology
    more info
     
    glutamatergic synapse ISO
    Inferred from Sequence Orthology
    more info
     
    intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    postsynaptic recycling endosome ISO
    Inferred from Sequence Orthology
    more info
     
    synapse IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    GRIP1-associated protein 1
    Names
    HCMV-interacting protein

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001290455.1NP_001277384.1  GRIP1-associated protein 1 isoform 1

      See identical proteins and their annotated locations for NP_001277384.1

      Status: VALIDATED

      Source sequence(s)
      AI642681, AL671995, BC138523
      Consensus CDS
      CCDS72334.1
      UniProtKB/TrEMBL
      A2AEW8
      Related
      ENSMUSP00000111339.2, ENSMUST00000115675.8
      Conserved Domains (1) summary
      pfam07888
      Location:2290
      CALCOCO1; Calcium binding and coiled-coil domain (CALCOCO1) like
    2. NM_001359289.1NP_001346218.1  GRIP1-associated protein 1 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AL671995
      Conserved Domains (1) summary
      cl25732
      Location:215560
      SMC_N; RecF/RecN/SMC N terminal domain
    3. NM_001359290.1NP_001346219.1  GRIP1-associated protein 1 isoform 4

      Status: VALIDATED

      Source sequence(s)
      AL671995
      Conserved Domains (2) summary
      cl25732
      Location:193480
      SMC_N; RecF/RecN/SMC N terminal domain
      cl26511
      Location:235732
      Neuromodulin_N; Gap junction protein N-terminal region
    4. NM_001359291.1NP_001346220.1  GRIP1-associated protein 1 isoform 5

      Status: VALIDATED

      Source sequence(s)
      AL671995
      Conserved Domains (1) summary
      cl25732
      Location:260602
      SMC_N; RecF/RecN/SMC N terminal domain
    5. NM_001359293.1NP_001346222.1  GRIP1-associated protein 1 isoform 6

      Status: VALIDATED

      Source sequence(s)
      AL671995
      Conserved Domains (2) summary
      TIGR04211
      Location:7108
      SH3_and_anchor; SH3 domain protein
      cl25732
      Location:170540
      SMC_N; RecF/RecN/SMC N terminal domain
    6. NM_207670.2NP_997553.1  GRIP1-associated protein 1 isoform 2

      See identical proteins and their annotated locations for NP_997553.1

      Status: VALIDATED

      Source sequence(s)
      AI642681, AL671995, BC138523
      Consensus CDS
      CCDS40844.1
      UniProtKB/Swiss-Prot
      Q8VD04
      UniProtKB/TrEMBL
      A2AEW8
      Related
      ENSMUSP00000068789.7, ENSMUST00000065932.13
      Conserved Domains (2) summary
      PLN00181
      Location:518708
      PLN00181; protein SPA1-RELATED; Provisional
      TIGR02168
      Location:260602
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000086.7 Reference GRCm38.p4 C57BL/6J

      Range
      7789961..7820567
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006527669.3XP_006527732.1  GRIP1-associated protein 1 isoform X1

      Conserved Domains (1) summary
      pfam07888
      Location:8306
      CALCOCO1; Calcium binding and coiled-coil domain (CALCOCO1) like
    2. XM_017318570.1XP_017174059.1  GRIP1-associated protein 1 isoform X16

    3. XM_006527674.3XP_006527737.1  GRIP1-associated protein 1 isoform X6

      Conserved Domains (1) summary
      cl23849
      Location:384494
      TrbI; Bacterial conjugation TrbI-like protein
    4. XM_006527672.3XP_006527735.1  GRIP1-associated protein 1 isoform X4

      Conserved Domains (1) summary
      cl23849
      Location:399509
      TrbI; Bacterial conjugation TrbI-like protein
    5. XM_006527670.3XP_006527733.1  GRIP1-associated protein 1 isoform X2

      Conserved Domains (3) summary
      PLN00181
      Location:556746
      PLN00181; protein SPA1-RELATED; Provisional
      COG0419
      Location:194650
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      pfam07888
      Location:53297
      CALCOCO1; Calcium binding and coiled-coil domain (CALCOCO1) like
    6. XM_006527676.3XP_006527739.1  GRIP1-associated protein 1 isoform X8

      Conserved Domains (2) summary
      cl15838
      Location:158257
      Phage_GPO; Phage capsid scaffolding protein (GPO) serine peptidase
      cl23849
      Location:370480
      TrbI; Bacterial conjugation TrbI-like protein
    7. XM_017318565.1XP_017174054.1  GRIP1-associated protein 1 isoform X7

    8. XM_017318566.1XP_017174055.1  GRIP1-associated protein 1 isoform X11

    9. XM_017318568.1XP_017174057.1  GRIP1-associated protein 1 isoform X13

      Conserved Domains (1) summary
      cl25732
      Location:260602
      SMC_N; RecF/RecN/SMC N terminal domain
    10. XM_006527671.3XP_006527734.1  GRIP1-associated protein 1 isoform X3

      Conserved Domains (1) summary
      pfam07888
      Location:2290
      CALCOCO1; Calcium binding and coiled-coil domain (CALCOCO1) like
    11. XM_006527677.3XP_006527740.1  GRIP1-associated protein 1 isoform X9

      Conserved Domains (1) summary
      cl25732
      Location:215560
      SMC_N; RecF/RecN/SMC N terminal domain
    12. XM_017318567.1XP_017174056.1  GRIP1-associated protein 1 isoform X12

      Conserved Domains (2) summary
      cl25732
      Location:193480
      SMC_N; RecF/RecN/SMC N terminal domain
      cl26511
      Location:235732
      Neuromodulin_N; Gap junction protein N-terminal region
    13. XM_006527673.3XP_006527736.1  GRIP1-associated protein 1 isoform X5

      Conserved Domains (1) summary
      TIGR02168
      Location:9622
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    14. XM_006527680.3XP_006527743.1  GRIP1-associated protein 1 isoform X10

      Conserved Domains (1) summary
      COG4985
      Location:27114
      COG4985; ABC-type phosphate transport system, auxiliary component [Inorganic ion transport and metabolism]
    15. XM_017318569.1XP_017174058.1  GRIP1-associated protein 1 isoform X15

      UniProtKB/TrEMBL
      A2AEW9
      Related
      ENSMUSP00000099218.3, ENSMUST00000101694.9
      Conserved Domains (2) summary
      TIGR04211
      Location:7108
      SH3_and_anchor; SH3 domain protein
      cl25732
      Location:170540
      SMC_N; RecF/RecN/SMC N terminal domain
    16. XM_006527681.3XP_006527744.1  GRIP1-associated protein 1 isoform X14

      Conserved Domains (1) summary
      COG4985
      Location:27114
      COG4985; ABC-type phosphate transport system, auxiliary component [Inorganic ion transport and metabolism]
    17. XM_006527683.3XP_006527746.1  GRIP1-associated protein 1 isoform X17

      Conserved Domains (2) summary
      COG4985
      Location:27114
      COG4985; ABC-type phosphate transport system, auxiliary component [Inorganic ion transport and metabolism]
      cl23849
      Location:307417
      TrbI; Bacterial conjugation TrbI-like protein
    18. XM_006527684.2XP_006527747.1  GRIP1-associated protein 1 isoform X18

      Conserved Domains (1) summary
      cl15838
      Location:40139
      Phage_GPO; Phage capsid scaffolding protein (GPO) serine peptidase
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