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    Ubqln2 ubiquilin 2 [ Mus musculus (house mouse) ]

    Gene ID: 54609, updated on 18-Sep-2018

    Summary

    Official Symbol
    Ubqln2provided by MGI
    Official Full Name
    ubiquilin 2provided by MGI
    Primary source
    MGI:MGI:1860283
    See related
    Ensembl:ENSMUSG00000050148 Vega:OTTMUSG00000019381
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Dsk2; Chap1; Plic2; Plic-2; HRIHFB2157
    Orthologs

    Genomic context

    See Ubqln2 in Genome Data Viewer
    Location:
    X; X F3
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) X NC_000086.7 (153498232..153501562)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) X NC_000086.6 (149932775..149936105)

    Chromosome X - NC_000086.7Genomic Context describing neighboring genes Neighboring gene Kruppel-like factor 8 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene Neighboring gene predicted gene, 39543 Neighboring gene cysteine-rich perinuclear theca 3

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    autophagy IEA
    Inferred from Electronic Annotation
    more info
     
    negative regulation of G protein-coupled receptor internalization ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of clathrin-dependent endocytosis ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of ER-associated ubiquitin-dependent protein catabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of autophagosome assembly ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of macroautophagy ISO
    Inferred from Sequence Orthology
    more info
     
    ubiquitin-dependent ERAD pathway ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    cytoplasmic vesicle IEA
    Inferred from Electronic Annotation
    more info
     
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    ubiquilin-2
    Names
    Ubiquitin-related protein
    protein linking IAP with cytoskeleton 2
    ubiquitin-like product Chap1/Dsk2

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_018798.2NP_061268.2  ubiquilin-2

      See identical proteins and their annotated locations for NP_061268.2

      Status: VALIDATED

      Source sequence(s)
      BC053022
      Consensus CDS
      CCDS30482.1
      UniProtKB/Swiss-Prot
      Q9QZM0
      Related
      ENSMUSP00000056888.8, OTTMUSP00000020893, ENSMUST00000060714.9, OTTMUST00000046253
      Conserved Domains (4) summary
      smart00727
      Location:396440
      STI1; Heat shock chaperonin-binding motif
      cd01808
      Location:33103
      hPLIC_N; Ubiquitin-like domain of hPLIC-1 and hPLIC2
      smart00213
      Location:33103
      UBQ; Ubiquitin homologues
      cd14399
      Location:595634
      UBA_PLICs; UBA domain of eukaryotic protein linking integrin-associated protein (IAP, also known as CD47) with cytoskeleton (PLIC) proteins

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000086.7 Reference GRCm38.p4 C57BL/6J

      Range
      153498232..153501562
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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