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    Ctnnal1 catenin (cadherin associated protein), alpha-like 1 [ Mus musculus (house mouse) ]

    Gene ID: 54366, updated on 14-Sep-2021

    Summary

    Official Symbol
    Ctnnal1provided by MGI
    Official Full Name
    catenin (cadherin associated protein), alpha-like 1provided by MGI
    Primary source
    MGI:MGI:1859649
    See related
    Ensembl:ENSMUSG00000038816
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    A; Cat; ACRP; C86009; Catnal1; AI616177; AW545119
    Expression
    Broad expression in bladder adult (RPKM 18.0), CNS E11.5 (RPKM 7.9) and 21 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Ctnnal1 in Genome Data Viewer
    Location:
    4; 4 B3
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (56810935..56865370, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (56810935..56865375, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 4 NC_000070.5 (56823807..56878083, complement)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene actin-like 7a Neighboring gene elongator complex protein 1 Neighboring gene actin binding transcription modulator Neighboring gene transmembrane protein 245 Neighboring gene predicted gene, 25053 Neighboring gene microRNA 32

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 
    • Targeted (3)  1 citation
    • Endonuclease-mediated (1) 

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables actin filament binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables cadherin binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within Rho protein signal transduction ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in cell adhesion IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    alpha-catulin
    Names
    alpha-catenin related protein
    catenin alpha-like 1
    catenin alpha-like protein 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_018761.3NP_061231.3  alpha-catulin

      See identical proteins and their annotated locations for NP_061231.3

      Status: VALIDATED

      Source sequence(s)
      AW536536, BC050070, BG064548, CF896873, CJ094037, CK794820
      Consensus CDS
      CCDS18200.1
      UniProtKB/Swiss-Prot
      O88327
      Related
      ENSMUSP00000036487.9, ENSMUST00000045142.15
      Conserved Domains (1) summary
      pfam01044
      Location:91674
      Vinculin; Vinculin family

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      56810935..56865370 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017320319.3XP_017175808.1  alpha-catulin isoform X1

      Conserved Domains (1) summary
      pfam01044
      Location:54411
      Vinculin; Vinculin family
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