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    Ctnnal1 catenin alpha like 1 [ Mus musculus (house mouse) ]

    Gene ID: 54366, updated on 26-Mar-2024


    Official Symbol
    Ctnnal1provided by MGI
    Official Full Name
    catenin alpha like 1provided by MGI
    Primary source
    See related
    Ensembl:ENSMUSG00000038816 AllianceGenome:MGI:1859649
    Gene type
    protein coding
    RefSeq status
    Mus musculus
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    ACRP; Catnal1
    Predicted to enable actin filament binding activity and cadherin binding activity. Predicted to be involved in cell adhesion. Predicted to act upstream of or within Rho protein signal transduction. Predicted to be located in cytosol. Orthologous to human CTNNAL1 (catenin alpha like 1). [provided by Alliance of Genome Resources, Apr 2022]
    Broad expression in bladder adult (RPKM 18.0), CNS E11.5 (RPKM 7.9) and 21 other tissues See more
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    Genomic context

    See Ctnnal1 in Genome Data Viewer
    4 B3; 4 31.66 cM
    Exon count:
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (56810935..56865370, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (56810935..56865375, complement)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene actin-like 7a Neighboring gene elongator complex protein 1 Neighboring gene actin binding transcription modulator Neighboring gene STARR-seq mESC enhancer starr_10312 Neighboring gene STARR-positive B cell enhancer ABC_E9083 Neighboring gene transmembrane protein 245 Neighboring gene predicted gene, 25053 Neighboring gene microRNA 32

    Genomic regions, transcripts, and products


    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a


    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?



    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 
    • Targeted (3)  1 citation
    • Endonuclease-mediated (3) 

    General gene information


    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables actin filament binding IEA
    Inferred from Electronic Annotation
    more info
    enables cadherin binding IEA
    Inferred from Electronic Annotation
    more info
    Process Evidence Code Pubs
    involved_in Rho protein signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    acts_upstream_of_or_within Rho protein signal transduction ISO
    Inferred from Sequence Orthology
    more info
    involved_in cell adhesion IEA
    Inferred from Electronic Annotation
    more info
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info

    General protein information

    Preferred Names
    alpha-catenin related protein
    catenin (cadherin associated protein), alpha-like 1
    catenin alpha-like protein 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_018761.3NP_061231.3  alpha-catulin

      See identical proteins and their annotated locations for NP_061231.3

      Status: VALIDATED

      Source sequence(s)
      AW536536, BC050070, BG064548, CF896873, CJ094037, CK794820
      Consensus CDS
      O88327, Q810J3
      ENSMUSP00000036487.9, ENSMUST00000045142.15
      Conserved Domains (1) summary
      Vinculin; Vinculin family

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J


    1. NC_000070.7 Reference GRCm39 C57BL/6J

      56810935..56865370 complement
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017320319.3XP_017175808.1  alpha-catulin isoform X1

      Conserved Domains (1) summary
      Vinculin; Vinculin family