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    Rpp30 ribonuclease P/MRP 30 subunit [ Mus musculus (house mouse) ]

    Gene ID: 54364, updated on 18-Sep-2024

    Summary

    Official Symbol
    Rpp30provided by MGI
    Official Full Name
    ribonuclease P/MRP 30 subunitprovided by MGI
    Primary source
    MGI:MGI:1859683
    See related
    Ensembl:ENSMUSG00000024800 AllianceGenome:MGI:1859683
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    TSG15; Rnasep2
    Summary
    Predicted to enable ribonuclease P RNA binding activity. Predicted to contribute to ribonuclease P activity. Predicted to be involved in RNA phosphodiester bond hydrolysis, endonucleolytic and tRNA 5'-leader removal. Predicted to act upstream of or within rRNA processing. Predicted to be located in nucleus. Predicted to be part of nucleolar ribonuclease P complex and ribonuclease MRP complex. Is expressed in several structures, including alimentary system; brain ventricular layer; olfactory epithelium; seminiferous cord; and vibrissa. Orthologous to human RPP30 (ribonuclease P/MRP subunit p30). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Broad expression in CNS E11.5 (RPKM 13.6), liver E14 (RPKM 10.6) and 20 other tissues See more
    Orthologs
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    Genomic context

    See Rpp30 in Genome Data Viewer
    Location:
    19 C2; 19 30.41 cM
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (36061118..36082173)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (36083689..36104773)

    Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA A830019P07 gene Neighboring gene peroxiredoxin 3 pseudogene Neighboring gene STARR-seq mESC enhancer starr_46016 Neighboring gene STARR-seq mESC enhancer starr_46017 Neighboring gene STARR-seq mESC enhancer starr_46018 Neighboring gene STARR-seq mESC enhancer starr_46019 Neighboring gene STARR-seq mESC enhancer starr_46020 Neighboring gene 5-hydroxytryptamine (serotonin) receptor 7 Neighboring gene STARR-positive B cell enhancer ABC_E7647 Neighboring gene STARR-positive B cell enhancer ABC_E5699 Neighboring gene ankyrin repeat domain 1 Neighboring gene predicted gene, 32081 Neighboring gene predicted gene, 32027

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables ribonuclease P RNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables ribonuclease P RNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables ribonuclease P activity IEA
    Inferred from Electronic Annotation
    more info
     
    contributes_to ribonuclease P activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in rRNA processing IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in tRNA 5'-leader removal IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in tRNA 5'-leader removal ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in tRNA processing IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    part_of multimeric ribonuclease P complex IEA
    Inferred from Electronic Annotation
    more info
     
    part_of multimeric ribonuclease P complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of nucleolar ribonuclease P complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
     
    part_of ribonuclease MRP complex IEA
    Inferred from Electronic Annotation
    more info
     
    part_of ribonuclease MRP complex ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    ribonuclease P protein subunit p30
    Names
    RNase P subunit 2
    RNaseP protein p30
    ribonuclease P/MRP 30kDa subunit
    ribonuclease P2
    NP_062301.3

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_019428.4NP_062301.3  ribonuclease P protein subunit p30

      See identical proteins and their annotated locations for NP_062301.3

      Status: VALIDATED

      Source sequence(s)
      AC119234
      Consensus CDS
      CCDS29770.1
      UniProtKB/Swiss-Prot
      O88796
      UniProtKB/TrEMBL
      Q6P6M0
      Related
      ENSMUSP00000025714.8, ENSMUST00000025714.9
      Conserved Domains (1) summary
      pfam01876
      Location:21224
      RNase_P_p30; RNase P subunit p30

    RNA

    1. NR_182659.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC119234

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000085.7 Reference GRCm39 C57BL/6J

      Range
      36061118..36082173
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)