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    Atf7ip activating transcription factor 7 interacting protein [ Mus musculus (house mouse) ]

    Gene ID: 54343, updated on 23-Jun-2021

    Summary

    Official Symbol
    Atf7ipprovided by MGI
    Official Full Name
    activating transcription factor 7 interacting proteinprovided by MGI
    Primary source
    MGI:MGI:1858965
    See related
    Ensembl:ENSMUSG00000030213
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    A; AM; Mcaf; Mcaf1; 2610204M12Rik; 5830415B17Rik
    Expression
    Ubiquitous expression in thymus adult (RPKM 11.1), whole brain E14.5 (RPKM 7.8) and 28 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Atf7ip in Genome Data Viewer
    Location:
    6; 6 G1
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (136495787..136587848)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (136518789..136610850)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 6 NC_000072.5 (136467372..136555900)

    Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene ribosomal protein L36A, pseudogene 3 Neighboring gene predicted gene, 44140 Neighboring gene coenzyme Q2 homolog, prenyltransferase pseudogene Neighboring gene phospholipase B domain containing 1 Neighboring gene predicted gene, 40409 Neighboring gene protein S100-A10 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables ATP hydrolysis activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables transcription corepressor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nuclear body ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    part_of transcription regulator complex IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    activating transcription factor 7-interacting protein 1
    Names
    ATFa-associated Modulator
    MBD1-containing chromatin-associated factor 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001388194.1NP_001375123.1  activating transcription factor 7-interacting protein 1 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC124779, AC134474
      Conserved Domains (5) summary
      PHA03247
      Location:8691213
      PHA03247; large tegument protein UL36; Provisional
      PHA03307
      Location:83362
      PHA03307; transcriptional regulator ICP4; Provisional
      COG5271
      Location:290626
      MDN1; Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis]
      pfam16788
      Location:601812
      ATF7IP_BD; ATF-interacting protein binding domain
      pfam16794
      Location:11991299
      fn3_4; Fibronectin-III type domain
    2. NM_001388195.1NP_001375124.1  activating transcription factor 7-interacting protein 1 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC124779, AC134474
      Conserved Domains (5) summary
      PHA03247
      Location:8681212
      PHA03247; large tegument protein UL36; Provisional
      PHA03307
      Location:83362
      PHA03307; transcriptional regulator ICP4; Provisional
      COG5271
      Location:290623
      MDN1; Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis]
      pfam16788
      Location:598811
      ATF7IP_BD; ATF-interacting protein binding domain
      pfam16794
      Location:11981298
      fn3_4; Fibronectin-III type domain
    3. NM_001388196.1NP_001375125.1  activating transcription factor 7-interacting protein 1 isoform 4

      Status: VALIDATED

      Source sequence(s)
      AC124779, AC134474
      Conserved Domains (5) summary
      PHA03247
      Location:8661208
      PHA03247; large tegument protein UL36; Provisional
      PHA03307
      Location:83362
      PHA03307; transcriptional regulator ICP4; Provisional
      COG5271
      Location:290623
      MDN1; Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis]
      pfam16788
      Location:598809
      ATF7IP_BD; ATF-interacting protein binding domain
      pfam16794
      Location:11941294
      fn3_4; Fibronectin-III type domain
    4. NM_001388197.1NP_001375126.1  activating transcription factor 7-interacting protein 1 isoform 5

      Status: VALIDATED

      Source sequence(s)
      AC124779, AC134474
      Conserved Domains (3) summary
      PHA03247
      Location:271615
      PHA03247; large tegument protein UL36; Provisional
      pfam16788
      Location:3214
      ATF7IP_BD; ATF-interacting protein binding domain
      pfam16794
      Location:601701
      fn3_4; Fibronectin-III type domain
    5. NM_019426.3NP_062299.2  activating transcription factor 7-interacting protein 1 isoform 3

      See identical proteins and their annotated locations for NP_062299.2

      Status: VALIDATED

      Source sequence(s)
      AC124779, AC134474
      Consensus CDS
      CCDS20651.1
      UniProtKB/Swiss-Prot
      Q7TT18
      Related
      ENSMUSP00000032335.7, ENSMUST00000032335.13
      Conserved Domains (5) summary
      PHA03247
      Location:8661210
      PHA03247; large tegument protein UL36; Provisional
      PHA03307
      Location:83362
      PHA03307; transcriptional regulator ICP4; Provisional
      COG5271
      Location:290623
      MDN1; Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis]
      pfam16788
      Location:598809
      ATF7IP_BD; ATF-interacting protein binding domain
      pfam16794
      Location:11961296
      fn3_4; Fibronectin-III type domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000072.7 Reference GRCm39 C57BL/6J

      Range
      136495787..136587848
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    2. NC_000072.7 Reference GRCm39 C57BL/6J

      Range
      136531089..136532543
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006506391.4XP_006506454.1  activating transcription factor 7-interacting protein 1 isoform X1

      Conserved Domains (5) summary
      PHA03247
      Location:8691213
      PHA03247; large tegument protein UL36; Provisional
      PHA03307
      Location:83362
      PHA03307; transcriptional regulator ICP4; Provisional
      COG5271
      Location:290626
      MDN1; Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis]
      pfam16788
      Location:601812
      ATF7IP_BD; ATF-interacting protein binding domain
      pfam16794
      Location:11991299
      fn3_4; Fibronectin-III type domain
    2. XM_036166296.1XP_036022189.1  activating transcription factor 7-interacting protein 1 isoform X2

      Conserved Domains (5) summary
      PHA03247
      Location:8661210
      PHA03247; large tegument protein UL36; Provisional
      PHA03307
      Location:83362
      PHA03307; transcriptional regulator ICP4; Provisional
      COG5271
      Location:290623
      MDN1; Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis]
      pfam16788
      Location:598809
      ATF7IP_BD; ATF-interacting protein binding domain
      pfam16794
      Location:11961296
      fn3_4; Fibronectin-III type domain
    3. XM_036166295.1XP_036022188.1  activating transcription factor 7-interacting protein 1 isoform X1

      Conserved Domains (5) summary
      PHA03247
      Location:8691213
      PHA03247; large tegument protein UL36; Provisional
      PHA03307
      Location:83362
      PHA03307; transcriptional regulator ICP4; Provisional
      COG5271
      Location:290626
      MDN1; Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis]
      pfam16788
      Location:601812
      ATF7IP_BD; ATF-interacting protein binding domain
      pfam16794
      Location:11991299
      fn3_4; Fibronectin-III type domain
    4. XM_017321681.3XP_017177170.1  activating transcription factor 7-interacting protein 1 isoform X2

      UniProtKB/Swiss-Prot
      Q7TT18
      Conserved Domains (5) summary
      PHA03247
      Location:8661210
      PHA03247; large tegument protein UL36; Provisional
      PHA03307
      Location:83362
      PHA03307; transcriptional regulator ICP4; Provisional
      COG5271
      Location:290623
      MDN1; Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis]
      pfam16788
      Location:598809
      ATF7IP_BD; ATF-interacting protein binding domain
      pfam16794
      Location:11961296
      fn3_4; Fibronectin-III type domain
    5. XM_006506390.5XP_006506453.1  activating transcription factor 7-interacting protein 1 isoform X3

      Conserved Domains (5) summary
      PHA03247
      Location:8771221
      PHA03247; large tegument protein UL36; Provisional
      PHA03307
      Location:91370
      PHA03307; transcriptional regulator ICP4; Provisional
      COG5271
      Location:298634
      MDN1; Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis]
      pfam16788
      Location:609820
      ATF7IP_BD; ATF-interacting protein binding domain
      pfam16794
      Location:12071307
      fn3_4; Fibronectin-III type domain
    6. XM_030255502.2XP_030111362.1  activating transcription factor 7-interacting protein 1 isoform X4

      Conserved Domains (5) summary
      PHA03247
      Location:8741218
      PHA03247; large tegument protein UL36; Provisional
      PHA03307
      Location:91370
      PHA03307; transcriptional regulator ICP4; Provisional
      COG5271
      Location:298631
      MDN1; Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis]
      pfam16788
      Location:606817
      ATF7IP_BD; ATF-interacting protein binding domain
      pfam16794
      Location:12041304
      fn3_4; Fibronectin-III type domain
    7. XM_006506388.5XP_006506451.2  activating transcription factor 7-interacting protein 1 isoform X1

      See identical proteins and their annotated locations for XP_006506451.2

      Conserved Domains (5) summary
      PHA03247
      Location:8691213
      PHA03247; large tegument protein UL36; Provisional
      PHA03307
      Location:83362
      PHA03307; transcriptional regulator ICP4; Provisional
      COG5271
      Location:290626
      MDN1; Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis]
      pfam16788
      Location:601812
      ATF7IP_BD; ATF-interacting protein binding domain
      pfam16794
      Location:11991299
      fn3_4; Fibronectin-III type domain
    8. XM_006506389.5XP_006506452.2  activating transcription factor 7-interacting protein 1 isoform X2

      See identical proteins and their annotated locations for XP_006506452.2

      UniProtKB/Swiss-Prot
      Q7TT18
      Conserved Domains (5) summary
      PHA03247
      Location:8661210
      PHA03247; large tegument protein UL36; Provisional
      PHA03307
      Location:83362
      PHA03307; transcriptional regulator ICP4; Provisional
      COG5271
      Location:290623
      MDN1; Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis]
      pfam16788
      Location:598809
      ATF7IP_BD; ATF-interacting protein binding domain
      pfam16794
      Location:11961296
      fn3_4; Fibronectin-III type domain
    9. XM_036166294.1XP_036022187.1  activating transcription factor 7-interacting protein 1 isoform X1

      Conserved Domains (5) summary
      PHA03247
      Location:8691213
      PHA03247; large tegument protein UL36; Provisional
      PHA03307
      Location:83362
      PHA03307; transcriptional regulator ICP4; Provisional
      COG5271
      Location:290626
      MDN1; Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis]
      pfam16788
      Location:601812
      ATF7IP_BD; ATF-interacting protein binding domain
      pfam16794
      Location:11991299
      fn3_4; Fibronectin-III type domain
    10. XM_030255503.2XP_030111363.1  activating transcription factor 7-interacting protein 1 isoform X2

      Conserved Domains (5) summary
      PHA03247
      Location:8661210
      PHA03247; large tegument protein UL36; Provisional
      PHA03307
      Location:83362
      PHA03307; transcriptional regulator ICP4; Provisional
      COG5271
      Location:290623
      MDN1; Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis]
      pfam16788
      Location:598809
      ATF7IP_BD; ATF-interacting protein binding domain
      pfam16794
      Location:11961296
      fn3_4; Fibronectin-III type domain
    11. XM_006506392.3XP_006506455.1  activating transcription factor 7-interacting protein 1 isoform X1

      See identical proteins and their annotated locations for XP_006506455.1

      Conserved Domains (5) summary
      PHA03247
      Location:8691213
      PHA03247; large tegument protein UL36; Provisional
      PHA03307
      Location:83362
      PHA03307; transcriptional regulator ICP4; Provisional
      COG5271
      Location:290626
      MDN1; Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis]
      pfam16788
      Location:601812
      ATF7IP_BD; ATF-interacting protein binding domain
      pfam16794
      Location:11991299
      fn3_4; Fibronectin-III type domain

    RNA

    1. XR_004942987.1 RNA Sequence

    2. XR_004942986.1 RNA Sequence

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