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    Actr1a ARP1 actin-related protein 1A, centractin alpha [ Mus musculus (house mouse) ]

    Gene ID: 54130, updated on 31-Jan-2019

    Summary

    Official Symbol
    Actr1aprovided by MGI
    Official Full Name
    ARP1 actin-related protein 1A, centractin alphaprovided by MGI
    Primary source
    MGI:MGI:1858964
    See related
    Ensembl:ENSMUSG00000025228
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Arp1; actin-RPV; alpha-Arp1
    Expression
    Ubiquitous expression in testis adult (RPKM 78.3), CNS E18 (RPKM 74.5) and 28 other tissues See more
    Orthologs

    Genomic context

    See Actr1a in Genome Data Viewer
    Location:
    19; 19 C3
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 19 NC_000085.6 (46376814..46395735, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 19 NC_000085.5 (46451304..46470225, complement)

    Chromosome 19 - NC_000085.6Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 2310034G01 gene Neighboring gene major facilitator superfamily domain containing 13a Neighboring gene SUFU negative regulator of hedgehog signaling Neighboring gene tripartite motif-containing 8

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    COPI-coated vesicle ISO
    Inferred from Sequence Orthology
    more info
     
    cell cortex region ISO
    Inferred from Sequence Orthology
    more info
     
    centriole ISO
    Inferred from Sequence Orthology
    more info
     
    centrosome ISO
    Inferred from Sequence Orthology
    more info
     
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    dynactin complex IEA
    Inferred from Electronic Annotation
    more info
     
    manchette ISO
    Inferred from Sequence Orthology
    more info
     
    microtubule cytoskeleton ISO
    Inferred from Sequence Orthology
    more info
     
    myelin sheath HDA PubMed 

    General protein information

    Preferred Names
    alpha-centractin
    Names
    ARP1 actin-related protein 1 homolog A, centractin alpha
    actin-related protein 1 alpha
    centrosome-associated actin homolog

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001365070.1NP_001351999.1  alpha-centractin isoform 2

      Status: VALIDATED

      Source sequence(s)
      AK019518, BY794369, CD776146
      Conserved Domains (1) summary
      cl17037
      Location:5307
      NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily
    2. NM_016860.2NP_058556.1  alpha-centractin isoform 1

      See identical proteins and their annotated locations for NP_058556.1

      Status: VALIDATED

      Source sequence(s)
      AB010297, BY794369, CD776146
      Consensus CDS
      CCDS29878.1
      UniProtKB/Swiss-Prot
      P61164
      Related
      ENSMUSP00000039844.4, ENSMUST00000040270.4
      Conserved Domains (1) summary
      cl17037
      Location:5376
      NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000085.6 Reference GRCm38.p4 C57BL/6J

      Range
      46376814..46395735 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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