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    Ddx20 DEAD (Asp-Glu-Ala-Asp) box polypeptide 20 [ Mus musculus (house mouse) ]

    Gene ID: 53975, updated on 31-Jan-2019

    Summary

    Official Symbol
    Ddx20provided by MGI
    Official Full Name
    DEAD (Asp-Glu-Ala-Asp) box polypeptide 20provided by MGI
    Primary source
    MGI:MGI:1858415
    See related
    Ensembl:ENSMUSG00000027905
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    dp103; GEMIN3
    Expression
    Broad expression in testis adult (RPKM 40.1), ovary adult (RPKM 10.1) and 23 other tissues See more
    Orthologs

    Genomic context

    See Ddx20 in Genome Data Viewer
    Location:
    3; 3 F2.2
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 3 NC_000069.6 (105678270..105688118, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 3 NC_000069.5 (105481380..105490489, complement)

    Chromosome 3 - NC_000069.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 34837 Neighboring gene potassium voltage-gated channel, Shal-related family, member 3, opposite strand Neighboring gene potassium voltage-gated channel, Shal-related family, member 3 Neighboring gene inka box actin regulator 2 Neighboring gene RAS-related protein 1a

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Homology

    Clone Names

    • MGC159174

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    helicase activity IEA
    Inferred from Electronic Annotation
    more info
     
    histone deacetylase binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
     
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein binding, bridging IDA
    Inferred from Direct Assay
    more info
    PubMed 
    protein domain specific binding ISO
    Inferred from Sequence Orthology
    more info
     
    repressing transcription factor binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    RNA splicing IEA
    Inferred from Electronic Annotation
    more info
     
    mRNA processing IEA
    Inferred from Electronic Annotation
    more info
     
    negative regulation of cell proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of transcription by RNA polymerase II IDA
    Inferred from Direct Assay
    more info
    PubMed 
    negative regulation of transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of transcription, DNA-templated ISO
    Inferred from Sequence Orthology
    more info
     
    oogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of apoptotic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of apoptotic process ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of steroid biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    spliceosomal snRNP assembly ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    RNA polymerase II transcription repressor complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    SMN complex ISO
    Inferred from Sequence Orthology
    more info
     
    SMN-Sm protein complex ISO
    Inferred from Sequence Orthology
    more info
     
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    transcriptional repressor complex IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    probable ATP-dependent RNA helicase DDX20
    Names
    DEAD box protein 20
    DEAD box protein DP 103
    DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 20
    ROSF-1
    component of gems 3
    gemin-3
    regulator of steroidogenic factor 1
    NP_059093.3
    XP_006501764.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_017397.3NP_059093.3  probable ATP-dependent RNA helicase DDX20

      See identical proteins and their annotated locations for NP_059093.3

      Status: PROVISIONAL

      Source sequence(s)
      BC125471
      Consensus CDS
      CCDS38581.1
      UniProtKB/Swiss-Prot
      Q9JJY4
      Related
      ENSMUSP00000088176.6, ENSMUST00000090680.10
      Conserved Domains (3) summary
      smart00487
      Location:78280
      DEXDc; DEAD-like helicases superfamily
      pfam00271
      Location:295405
      Helicase_C; Helicase conserved C-terminal domain
      cl21455
      Location:65266
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000069.6 Reference GRCm38.p4 C57BL/6J

      Range
      105678270..105688118 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006501701.3XP_006501764.1  probable ATP-dependent RNA helicase DDX20 isoform X1

      See identical proteins and their annotated locations for XP_006501764.1

      UniProtKB/Swiss-Prot
      Q9JJY4
      Conserved Domains (3) summary
      smart00487
      Location:78280
      DEXDc; DEAD-like helicases superfamily
      pfam00271
      Location:295405
      Helicase_C; Helicase conserved C-terminal domain
      cl21455
      Location:65266
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
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