Format

Send to:

Choose Destination
    • Showing Current items.

    Rab11a RAB11A, member RAS oncogene family [ Mus musculus (house mouse) ]

    Gene ID: 53869, updated on 9-Sep-2018

    Summary

    Official Symbol
    Rab11aprovided by MGI
    Official Full Name
    RAB11A, member RAS oncogene familyprovided by MGI
    Primary source
    MGI:MGI:1858202
    See related
    Ensembl:ENSMUSG00000004771 Vega:OTTMUSG00000036848
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Expression
    Ubiquitous expression in CNS E18 (RPKM 50.9), bladder adult (RPKM 49.3) and 28 other tissues See more
    Orthologs

    Genomic context

    See Rab11a in Genome Data Viewer
    Location:
    9; 9 C
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 9 NC_000075.6 (64715300..64737756, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 9 NC_000075.5 (64563107..64585563, complement)

    Chromosome 9 - NC_000075.6Genomic Context describing neighboring genes Neighboring gene DIS3 like exosome 3'-5' exoribonuclease Neighboring gene multiple EGF-like-domains 11 Neighboring gene predicted gene, 36311 Neighboring gene nuclear encoded tRNA glutamine 9 (anticodon CTG) Neighboring gene predicted gene, 36365

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    GTP binding ISO
    Inferred from Sequence Orthology
    more info
     
    GTPase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    GTPase activity ISO
    Inferred from Sequence Orthology
    more info
     
    microtubule binding ISO
    Inferred from Sequence Orthology
    more info
     
    myosin V binding ISO
    Inferred from Sequence Orthology
    more info
     
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    Rab protein signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    astral microtubule organization ISO
    Inferred from Sequence Orthology
    more info
     
    cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    establishment of protein localization to membrane ISO
    Inferred from Sequence Orthology
    more info
     
    establishment of protein localization to organelle ISO
    Inferred from Sequence Orthology
    more info
     
    establishment of vesicle localization ISO
    Inferred from Sequence Orthology
    more info
     
    exocytosis IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    exosomal secretion ISO
    Inferred from Sequence Orthology
    more info
     
    intracellular protein transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    melanosome transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    melanosome transport IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    mitotic metaphase plate congression ISO
    Inferred from Sequence Orthology
    more info
     
    mitotic spindle assembly ISO
    Inferred from Sequence Orthology
    more info
     
    multivesicular body assembly ISO
    Inferred from Sequence Orthology
    more info
     
    neuron projection development ISO
    Inferred from Sequence Orthology
    more info
     
    neurotransmitter receptor transport, endosome to postsynaptic membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    neurotransmitter receptor transport, endosome to postsynaptic membrane ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of G2/M transition of mitotic cell cycle ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of axon extension IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of epithelial cell migration ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of protein localization to plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    protein localization to plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    regulation of cytokinesis ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of long-term neuronal synaptic plasticity ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of multivesicular body size ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of protein transport ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of vesicle-mediated transport ISO
    Inferred from Sequence Orthology
    more info
     
    vesicle-mediated transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    vesicle-mediated transport ISO
    Inferred from Sequence Orthology
    more info
     
    vesicle-mediated transport in synapse ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    Schaffer collateral - CA1 synapse ISO
    Inferred from Sequence Orthology
    more info
     
    axon IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    axon IDA
    Inferred from Direct Assay
    more info
    PubMed 
    colocalizes_with centrosome ISO
    Inferred from Sequence Orthology
    more info
     
    cleavage furrow ISO
    Inferred from Sequence Orthology
    more info
     
    cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cytoplasmic vesicle ISO
    Inferred from Sequence Orthology
    more info
     
    endosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    extracellular exosome ISO
    Inferred from Sequence Orthology
    more info
     
    glutamatergic synapse ISO
    Inferred from Sequence Orthology
    more info
     
    intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
     
    colocalizes_with kinetochore microtubule ISO
    Inferred from Sequence Orthology
    more info
     
    membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    microtubule organizing center ISO
    Inferred from Sequence Orthology
    more info
     
    mitochondrion HDA PubMed 
    multivesicular body ISO
    Inferred from Sequence Orthology
    more info
     
    perinuclear region of cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    phagocytic vesicle ISO
    Inferred from Sequence Orthology
    more info
     
    plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    postsynaptic recycling endosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    postsynaptic recycling endosome ISO
    Inferred from Sequence Orthology
    more info
     
    protein-containing complex ISO
    Inferred from Sequence Orthology
    more info
     
    recycling endosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    recycling endosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    recycling endosome ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    spindle pole ISO
    Inferred from Sequence Orthology
    more info
     
    trans-Golgi network ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    transport vesicle IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    transport vesicle ISO
    Inferred from Sequence Orthology
    more info
     
    vesicle ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    ras-related protein Rab-11A
    Names
    rab-11

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_017382.5NP_059078.2  ras-related protein Rab-11A

      See identical proteins and their annotated locations for NP_059078.2

      Status: VALIDATED

      Source sequence(s)
      AC147560, AK031143, AK147122
      Consensus CDS
      CCDS23282.1
      UniProtKB/Swiss-Prot
      P62492
      UniProtKB/TrEMBL
      Q0PD45
      Related
      ENSMUSP00000129163.1, OTTMUSP00000052667, ENSMUST00000172298.7, OTTMUST00000094624
      Conserved Domains (1) summary
      cd01868
      Location:9173
      Rab11_like; Rab GTPase family 11 (Rab11)-like includes Rab11a, Rab11b, and Rab25

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000075.6 Reference GRCm38.p4 C57BL/6J

      Range
      64715300..64737756 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Support Center