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    Rab11a RAB11A, member RAS oncogene family [ Mus musculus (house mouse) ]

    Gene ID: 53869, updated on 22-Aug-2021

    Summary

    Official Symbol
    Rab11aprovided by MGI
    Official Full Name
    RAB11A, member RAS oncogene familyprovided by MGI
    Primary source
    MGI:MGI:1858202
    See related
    Ensembl:ENSMUSG00000004771
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Expression
    Ubiquitous expression in CNS E18 (RPKM 50.9), bladder adult (RPKM 49.3) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Rab11a in Genome Data Viewer
    Location:
    9; 9 C
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (64622582..64645038, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (64715300..64737756, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 9 NC_000075.5 (64563107..64585563, complement)

    Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene DIS3 like exosome 3'-5' exoribonuclease Neighboring gene multiple EGF-like-domains 11 Neighboring gene predicted gene, 36311 Neighboring gene nuclear encoded tRNA glutamine 9 (anticodon CTG) Neighboring gene predicted gene, 36365

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables G protein activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables GTP binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables GTPase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables microtubule binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables myosin V binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in amyloid-beta clearance by transcytosis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in astral microtubule organization ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in establishment of protein localization to membrane ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in establishment of protein localization to organelle ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in establishment of vesicle localization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in exocytosis IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in exosomal secretion ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in melanosome transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in melanosome transport IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in mitotic metaphase plate congression ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in mitotic spindle assembly ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in multivesicular body assembly ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in neuron projection development ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in neurotransmitter receptor transport, endosome to postsynaptic membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in neurotransmitter receptor transport, endosome to postsynaptic membrane ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of G2/M transition of mitotic cell cycle ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within positive regulation of axon extension IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of epithelial cell migration ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of protein localization to plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within protein localization to cell surface IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in protein localization to plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in regulation of cytokinesis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of long-term neuronal synaptic plasticity ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of multivesicular body size ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of protein transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of vesicle-mediated transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in vesicle-mediated transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in vesicle-mediated transport in synapse ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    is_active_in axon IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in axon IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in centriolar satellite ISO
    Inferred from Sequence Orthology
    more info
     
    colocalizes_with centrosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in centrosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cleavage furrow ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cytoplasmic vesicle ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in endosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in extracellular exosome ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in glutamatergic synapse ISO
    Inferred from Sequence Orthology
    more info
     
    located_in intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
     
    colocalizes_with kinetochore microtubule ISO
    Inferred from Sequence Orthology
    more info
     
    located_in membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in mitochondrion HDA PubMed 
    located_in multivesicular body ISO
    Inferred from Sequence Orthology
    more info
     
    located_in perinuclear region of cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in phagocytic vesicle ISO
    Inferred from Sequence Orthology
    more info
     
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in postsynaptic recycling endosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    is_active_in postsynaptic recycling endosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in postsynaptic recycling endosome ISO
    Inferred from Sequence Orthology
    more info
     
    part_of protein-containing complex ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in recycling endosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in recycling endosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in recycling endosome ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    located_in spindle pole ISO
    Inferred from Sequence Orthology
    more info
     
    located_in trans-Golgi network ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    is_active_in transport vesicle IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in transport vesicle ISO
    Inferred from Sequence Orthology
    more info
     
    located_in vesicle ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    ras-related protein Rab-11A
    Names
    rab-11
    NP_059078.2

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_017382.5NP_059078.2  ras-related protein Rab-11A

      See identical proteins and their annotated locations for NP_059078.2

      Status: VALIDATED

      Source sequence(s)
      AC147560, AK031143, AK147122
      Consensus CDS
      CCDS23282.1
      UniProtKB/Swiss-Prot
      P62492
      UniProtKB/TrEMBL
      Q0PD45
      Related
      ENSMUSP00000129163.2, ENSMUST00000172298.8
      Conserved Domains (1) summary
      cd01868
      Location:9173
      Rab11_like; Rab GTPase family 11 (Rab11)-like includes Rab11a, Rab11b, and Rab25

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000075.7 Reference GRCm39 C57BL/6J

      Range
      64622582..64645038 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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