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    Vti1b vesicle transport through interaction with t-SNAREs 1B [ Mus musculus (house mouse) ]

    Gene ID: 53612, updated on 23-Jun-2021

    Summary

    Official Symbol
    Vti1bprovided by MGI
    Official Full Name
    vesicle transport through interaction with t-SNAREs 1Bprovided by MGI
    Primary source
    MGI:MGI:1855688
    See related
    Ensembl:ENSMUSG00000021124
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Vti1; GES30; SNARE; MVti1b; AU015348; Vti1-rp1
    Expression
    Ubiquitous expression in cortex adult (RPKM 37.7), frontal lobe adult (RPKM 36.2) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Vti1b in Genome Data Viewer
    Location:
    12; 12 C3
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (79202791..79219428, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (79156017..79172685, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 12 NC_000078.5 (80257004..80273445, complement)

    Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene ribosomal protein large PO subunit pseudogene Neighboring gene arginase type II Neighboring gene predicted gene, 40462 Neighboring gene retinol dehydrogenase 11 Neighboring gene retinol dehydrogenase 12

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables SNAP receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables SNARE binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables SNARE binding ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    enables chloride channel inhibitor activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in Golgi to vacuole transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in intra-Golgi vesicle-mediated transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in intracellular protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in macroautophagy IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in regulation of protein localization to plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in regulation of protein localization to plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in retrograde transport, endosome to Golgi IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in vesicle fusion IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in vesicle fusion with Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in vesicle-mediated transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in ER to Golgi transport vesicle membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    is_active_in Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in Golgi apparatus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
     
    part_of SNARE complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of SNARE complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in anchored component of membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in early endosome membrane ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in endoplasmic reticulum membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in endosome IEA
    Inferred from Electronic Annotation
    more info
     
    located_in integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in late endosome membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in late endosome membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in lysosomal membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in lysosome IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in neuronal cell body ISO
    Inferred from Sequence Orthology
    more info
     
    located_in perinuclear region of cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in perinuclear region of cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in recycling endosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in recycling endosome membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in synaptic vesicle ISO
    Inferred from Sequence Orthology
    more info
     
    located_in vesicle ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    vesicle transport through interaction with t-SNAREs homolog 1B
    Names
    A novel SNARE
    Soluble N-ethylmaleimide-sensitive factor-attachment protein receptor
    vesicle transport through interaction with t-SNAREs 1B homolog
    vesicle transport v-SNARE protein Vti1-like 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001364374.1NP_001351303.1  vesicle transport through interaction with t-SNAREs homolog 1B isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC154585
      Conserved Domains (2) summary
      cd15890
      Location:75136
      SNARE_Vti1b; SNARE motif of Vti1b-like
      pfam05008
      Location:135
      V-SNARE; Vesicle transport v-SNARE protein N-terminus
    2. NM_016800.3NP_058080.2  vesicle transport through interaction with t-SNAREs homolog 1B isoform 1

      See identical proteins and their annotated locations for NP_058080.2

      Status: VALIDATED

      Source sequence(s)
      BQ177030, BY280269, CX239415
      Consensus CDS
      CCDS26008.1
      UniProtKB/TrEMBL
      Q91XH6
      Related
      ENSMUSP00000057462.7, ENSMUST00000055262.13
      Conserved Domains (2) summary
      cd15890
      Location:136197
      SNARE_Vti1b; SNARE motif of Vti1b-like
      pfam05008
      Location:1896
      V-SNARE; Vesicle transport v-SNARE protein N-terminus

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000078.7 Reference GRCm39 C57BL/6J

      Range
      79202791..79219428 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011244143.3XP_011242445.1  vesicle transport through interaction with t-SNAREs homolog 1B isoform X2

      See identical proteins and their annotated locations for XP_011242445.1

      Conserved Domains (2) summary
      cd15890
      Location:75136
      SNARE_Vti1b; SNARE motif of Vti1b-like
      pfam05008
      Location:135
      V-SNARE; Vesicle transport v-SNARE protein N-terminus
    2. XM_036157529.1XP_036013422.1  vesicle transport through interaction with t-SNAREs homolog 1B isoform X1

      Conserved Domains (2) summary
      cd15890
      Location:133194
      SNARE_Vti1b; SNARE motif of Vti1b-like
      pfam05008
      Location:3693
      V-SNARE; Vesicle transport v-SNARE protein N-terminus
    3. XM_036157530.1XP_036013423.1  vesicle transport through interaction with t-SNAREs homolog 1B isoform X3

      Conserved Domains (1) summary
      cd15890
      Location:2283
      SNARE_Vti1b; SNARE motif of Vti1b-like
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