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    Ybx2 Y box protein 2 [ Mus musculus (house mouse) ]

    Gene ID: 53422, updated on 23-Oct-2018

    Summary

    Official Symbol
    Ybx2provided by MGI
    Official Full Name
    Y box protein 2provided by MGI
    Primary source
    MGI:MGI:1096372
    See related
    Ensembl:ENSMUSG00000018554 Vega:OTTMUSG00000006029
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Msy2
    Expression
    Biased expression in testis adult (RPKM 508.1) and colon adult (RPKM 19.1) See more
    Orthologs

    Genomic context

    See Ybx2 in Genome Data Viewer
    Location:
    11; 11 B3
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 11 NC_000077.6 (69935834..69941604)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (69749401..69755101)

    Chromosome 11 - NC_000077.6Genomic Context describing neighboring genes Neighboring gene neuralized E3 ubiquitin protein ligase 4 Neighboring gene G protein pathway suppressor 2 Neighboring gene eukaryotic translation initiation factor 5A Neighboring gene solute carrier family 2 (facilitated glucose transporter), member 4 Neighboring gene cofilin 1, non-muscle pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC118270

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    RNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    chromatin binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    lipid binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    mRNA 3'-UTR binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    mRNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
     
    ribonucleoprotein complex binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    translation regulator activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    mRNA stabilization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of binding IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of translation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    oogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of cold-induced thermogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of transcription, DNA-templated IEA
    Inferred from Electronic Annotation
    more info
     
    spermatid development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    fibrillar center ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    polysome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    ribonucleoprotein complex IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    Y-box-binding protein 2
    Names
    Y-box protein MSY2
    germ cell-specific Y-box-binding protein

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001347634.2NP_001334563.1  Y-box-binding protein 2 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AL596185
      Consensus CDS
      CCDS83830.1
      UniProtKB/TrEMBL
      A0A0A0MQD2
    2. NM_016875.3NP_058571.2  Y-box-binding protein 2 isoform 1

      See identical proteins and their annotated locations for NP_058571.2

      Status: VALIDATED

      Source sequence(s)
      AK131786, AK161439, AL596185, BC100454, DV661016
      Consensus CDS
      CCDS36200.1
      UniProtKB/TrEMBL
      B2RUF0, Q3TTC8, Q497N3
      Related
      ENSMUSP00000018698.5, OTTMUSP00000006276, ENSMUST00000018698.11
      Conserved Domains (1) summary
      pfam00313
      Location:95164
      CSD; 'Cold-shock' DNA-binding domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000077.6 Reference GRCm38.p4 C57BL/6J

      Range
      69935834..69941604
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006533738.3XP_006533801.1  Y-box-binding protein 2 isoform X1

      See identical proteins and their annotated locations for XP_006533801.1

      Conserved Domains (1) summary
      pfam00313
      Location:95164
      CSD; 'Cold-shock' DNA-binding domain
    2. XM_006533739.3XP_006533802.1  Y-box-binding protein 2 isoform X2

      See identical proteins and their annotated locations for XP_006533802.1

      Conserved Domains (1) summary
      cd04458
      Location:97126
      CSP_CDS; Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea. CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box protein. ...
    3. XM_006533740.1XP_006533803.1  Y-box-binding protein 2 isoform X3

      See identical proteins and their annotated locations for XP_006533803.1

      Conserved Domains (1) summary
      pfam00313
      Location:1887
      CSD; 'Cold-shock' DNA-binding domain
    4. XM_006533741.3XP_006533804.1  Y-box-binding protein 2 isoform X4

      Related
      ENSMUSP00000104242.2, OTTMUSP00000006277, ENSMUST00000108601.2, OTTMUST00000013543
      Conserved Domains (1) summary
      pfam00313
      Location:1887
      CSD; 'Cold-shock' DNA-binding domain
    5. XM_006533742.1XP_006533805.1  Y-box-binding protein 2 isoform X5

      See identical proteins and their annotated locations for XP_006533805.1

    RNA

    1. XR_001780025.1 RNA Sequence

    Reference GRCm38.p4 NOD/MrkTac

    Genomic

    1. NT_187026.1 Reference GRCm38.p4 NOD/MrkTac

      Range
      40429..46129
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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