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    Pgrmc1 progesterone receptor membrane component 1 [ Mus musculus (house mouse) ]

    Gene ID: 53328, updated on 6-Sep-2021

    Summary

    Official Symbol
    Pgrmc1provided by MGI
    Official Full Name
    progesterone receptor membrane component 1provided by MGI
    Primary source
    MGI:MGI:1858305
    See related
    Ensembl:ENSMUSG00000006373
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    P; Ve; mPR; HPR6; PPMR; Vema; HPR6.6; AA415812
    Expression
    Ubiquitous expression in liver adult (RPKM 269.7), adrenal adult (RPKM 243.6) and 27 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Pgrmc1 in Genome Data Viewer
    Location:
    X; X A3.3
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) X NC_000086.8 (35861846..35869732)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (36598193..36606079)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) X NC_000086.6 (34138220..34146074)

    Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene predicted gene, 22364 Neighboring gene predicted gene 14569 Neighboring gene A kinase (PRKA) anchor protein 17B Neighboring gene ribosomal protein L7, pseudogene 9

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables heme binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables heme binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables lipid binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein homodimerization activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables steroid binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in associative learning ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in heme biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in memory ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in modification of synaptic structure ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of synapse organization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of protein localization to plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in cell body ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in endomembrane system IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
     
    located_in integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in intracellular membrane-bounded organelle IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in mitochondrial outer membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
     
    located_in neuron projection ISO
    Inferred from Sequence Orthology
    more info
     
    located_in neuronal cell body ISO
    Inferred from Sequence Orthology
    more info
     
    located_in synapse ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    membrane-associated progesterone receptor component 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_016783.4NP_058063.2  membrane-associated progesterone receptor component 1

      See identical proteins and their annotated locations for NP_058063.2

      Status: VALIDATED

      Source sequence(s)
      AK153272, BP770245, CK618071
      Consensus CDS
      CCDS30060.1
      UniProtKB/Swiss-Prot
      O55022
      UniProtKB/TrEMBL
      Q3TXU8
      Related
      ENSMUSP00000073061.7, ENSMUST00000073339.7
      Conserved Domains (1) summary
      pfam00173
      Location:72136
      Cyt-b5; Cytochrome b5-like Heme/Steroid binding domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000086.8 Reference GRCm39 C57BL/6J

      Range
      35861846..35869732
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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