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    Plrg1 pleiotropic regulator 1 [ Mus musculus (house mouse) ]

    Gene ID: 53317, updated on 23-Jun-2021

    Summary

    Official Symbol
    Plrg1provided by MGI
    Official Full Name
    pleiotropic regulator 1provided by MGI
    Primary source
    MGI:MGI:1858197
    See related
    Ensembl:ENSMUSG00000027998
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Tan; C80566; Tango4; AA958940
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 34.5), CNS E14 (RPKM 30.5) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Plrg1 in Genome Data Viewer
    Location:
    3; 3 E3
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (82962845..82979598)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (83055538..83072291)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 3 NC_000069.5 (82859460..82876213)

    Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 40075 Neighboring gene fibrinogen beta chain Neighboring gene predicted gene 10710 Neighboring gene dachsous cadherin related 2 Neighboring gene predicted gene, 54183

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Component Evidence Code Pubs
    part_of Cul4-RING E3 ubiquitin ligase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of DNA replication factor A complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of Prp19 complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of U2-type catalytic step 2 spliceosome ISO
    Inferred from Sequence Orthology
    more info
     
    part_of catalytic step 2 spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of catalytic step 2 spliceosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in fibrillar center ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nuclear membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nuclear speck ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    part_of spliceosomal complex IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    pleiotropic regulator 1
    Names
    pleiotropic regulator 1, PRL1 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_016784.3NP_058064.2  pleiotropic regulator 1

      See identical proteins and their annotated locations for NP_058064.2

      Status: PROVISIONAL

      Source sequence(s)
      AK077197
      Consensus CDS
      CCDS17433.1
      UniProtKB/Swiss-Prot
      Q922V4
      Related
      ENSMUSP00000114968.2, ENSMUST00000150268.8
      Conserved Domains (3) summary
      COG2319
      Location:192488
      WD40; WD40 repeat [General function prediction only]
      cd00200
      Location:195489
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:208243
      7WD40; WD40 repeat [structural motif]

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000069.7 Reference GRCm39 C57BL/6J

      Range
      82962845..82979598
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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