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    Krr1 KRR1, small subunit (SSU) processome component, homolog (yeast) [ Mus musculus (house mouse) ]

    Gene ID: 52705, updated on 26-Sep-2022

    Summary

    Official Symbol
    Krr1provided by MGI
    Official Full Name
    KRR1, small subunit (SSU) processome component, homolog (yeast)provided by MGI
    Primary source
    MGI:MGI:1289274
    See related
    Ensembl:ENSMUSG00000063334 AllianceGenome:MGI:1289274
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Hrb2; D10Ertd773e; 2610511F02Rik
    Summary
    Predicted to enable RNA binding activity. Predicted to act upstream of or within rRNA processing. Predicted to be located in chromosome; intercellular bridge; and nucleoplasm. Predicted to be part of small-subunit processome. Predicted to be active in nucleolus. Is expressed in axial skeleton; brain; esophagus; head mesenchyme; and lung. Orthologous to human KRR1 (KRR1 small subunit processome component homolog). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 9.9), bladder adult (RPKM 6.8) and 24 other tissues See more
    Orthologs
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    Genomic context

    See Krr1 in Genome Data Viewer
    Location:
    10 D1- D2; 10 59.97 cM
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (111808600..111824335)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (111972695..111988430)

    Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene S-adenosylmethionine decarboxylase, pseudogene 3 pseudogene Neighboring gene predicted gene, 20758 Neighboring gene GLI pathogenesis-related 1 (glioma) Neighboring gene calcyphosphine 2 pseudogene Neighboring gene GLI pathogenesis-related 1 like 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within rRNA processing IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within ribosome biogenesis IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in chromosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in intercellular bridge ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleolus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    part_of small-subunit processome IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    KRR1 small subunit processome component homolog
    Names
    HIV-1 Rev binding protein 2
    HIV-1 Rev-binding protein 2 homolog
    KRR-R motif-containing protein 1
    KRR1, small subunit processome component

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_178610.4NP_848725.2  KRR1 small subunit processome component homolog

      See identical proteins and their annotated locations for NP_848725.2

      Status: VALIDATED

      Source sequence(s)
      AC167231, AK041854, CD547185
      Consensus CDS
      CCDS24168.1
      UniProtKB/Swiss-Prot
      Q8BGA5, Q8C029
      Related
      ENSMUSP00000125746.2, ENSMUST00000163048.8
      Conserved Domains (2) summary
      smart00322
      Location:157207
      KH; K homology RNA-binding domain
      COG1094
      Location:55240
      Krr1; rRNA processing protein Krr1/Pno1, contains KH domain [Translation, ribosomal structure and biogenesis]

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000076.7 Reference GRCm39 C57BL/6J

      Range
      111808600..111824335
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)