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    Txndc17 thioredoxin domain containing 17 [ Mus musculus (house mouse) ]

    Gene ID: 52700, updated on 8-Aug-2021

    Summary

    Official Symbol
    Txndc17provided by MGI
    Official Full Name
    thioredoxin domain containing 17provided by MGI
    Primary source
    MGI:MGI:1289248
    See related
    Ensembl:ENSMUSG00000020803
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    TRP; Txn; TRP14; Txnl5; D11Ertd672; D11Ertd672e; 4831443O22Rik
    Expression
    Ubiquitous expression in placenta adult (RPKM 53.8), large intestine adult (RPKM 37.7) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Txndc17 in Genome Data Viewer
    Location:
    11 B4; 11 43.92 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (72098380..72101313)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (72207554..72210487)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (72021056..72023989)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene PITPNM family member 3 Neighboring gene predicted gene, 46286 Neighboring gene RIKEN cDNA 4933427D14 gene Neighboring gene RIKEN cDNA 4930563E22 gene Neighboring gene mediator complex subunit 31 Neighboring gene solute carrier family 13 (sodium-dependent citrate transporter), member 5 Neighboring gene predicted gene, 34252

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables peroxidase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein-disulfide reductase (NAD(P)) activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables protein-disulfide reductase (NAD(P)) activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in tumor necrosis factor-mediated signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    thioredoxin domain-containing protein 17
    Names
    14 kDa thioredoxin-related protein
    protein 42-9-9
    putative 42-9-9 protein
    thioredoxin-like 5
    thioredoxin-like protein 5

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_026559.3NP_080835.1  thioredoxin domain-containing protein 17

      See identical proteins and their annotated locations for NP_080835.1

      Status: VALIDATED

      Source sequence(s)
      AK076425
      Consensus CDS
      CCDS24980.1
      UniProtKB/Swiss-Prot
      Q9CQM5
      Related
      ENSMUSP00000021158.4, ENSMUST00000021158.4
      Conserved Domains (1) summary
      cd02952
      Location:4121
      TRP14_like; Human TRX-related protein 14 (TRP14)-like family; composed of proteins similar to TRP14, a 14kD cytosolic protein that shows disulfide reductase activity in vitro with a different substrate specificity compared with another human cytosolic protein, TRX1. ...

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      72098380..72101313
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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