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    Ccdc69 coiled-coil domain containing 69 [ Mus musculus (house mouse) ]

    Gene ID: 52570, updated on 27-Nov-2024

    Summary

    Official Symbol
    Ccdc69provided by MGI
    Official Full Name
    coiled-coil domain containing 69provided by MGI
    Primary source
    MGI:MGI:1196234
    See related
    Ensembl:ENSMUSG00000049588 AllianceGenome:MGI:1196234
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    D11Ertd461e; 2210021E03Rik
    Summary
    Predicted to enable microtubule binding activity. Predicted to be involved in spindle midzone assembly. Predicted to be located in spindle midzone. Predicted to be active in nucleus. Predicted to colocalize with cytoplasm. Orthologous to human CCDC69 (coiled-coil domain containing 69). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Broad expression in bladder adult (RPKM 8.4), thymus adult (RPKM 3.9) and 16 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Ccdc69 in Genome Data Viewer
    Location:
    11 B1.3; 11 32.13 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (54940559..54969608, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (55049733..55078666, complement)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene TNFAIP3 interacting protein 1 Neighboring gene STARR-positive B cell enhancer ABC_E1824 Neighboring gene 40S ribosomal protein S11-like Neighboring gene STARR-seq mESC enhancer starr_29522 Neighboring gene STARR-seq mESC enhancer starr_29523 Neighboring gene annexin A6 Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:54836566-54836859 Neighboring gene predicted gene, 19911 Neighboring gene STARR-seq mESC enhancer starr_29527 Neighboring gene STARR-positive B cell enhancer ABC_E161 Neighboring gene STARR-positive B cell enhancer ABC_E8406 Neighboring gene GM2 ganglioside activator protein Neighboring gene ATP synthase peripheral stalk-membrane subunit b, pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 
    • Targeted (2) 

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables microtubule binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in spindle midzone assembly ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in spindle midzone assembly ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    colocalizes_with cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in midbody IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in spindle midzone ISO
    Inferred from Sequence Orthology
    more info
     
    located_in spindle midzone ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    coiled-coil domain-containing protein 69

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_177471.4NP_803422.2  coiled-coil domain-containing protein 69

      See identical proteins and their annotated locations for NP_803422.2

      Status: VALIDATED

      Source sequence(s)
      AK008760, AK079810
      Consensus CDS
      CCDS36155.1
      UniProtKB/Swiss-Prot
      Q3TCJ8, Q8C515
      Related
      ENSMUSP00000054840.7, ENSMUST00000055040.13

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      54940559..54969608 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036156828.1XP_036012721.1  coiled-coil domain-containing protein 69 isoform X1

      UniProtKB/Swiss-Prot
      Q3TCJ8, Q8C515
    2. XM_011249125.2XP_011247427.1  coiled-coil domain-containing protein 69 isoform X1

      See identical proteins and their annotated locations for XP_011247427.1

      UniProtKB/Swiss-Prot
      Q3TCJ8, Q8C515