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    Sgta small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha [ Mus musculus (house mouse) ]

    Gene ID: 52551, updated on 22-Aug-2021

    Summary

    Official Symbol
    Sgtaprovided by MGI
    Official Full Name
    small glutamine-rich tetratricopeptide repeat (TPR)-containing, alphaprovided by MGI
    Primary source
    MGI:MGI:1098703
    See related
    Ensembl:ENSMUSG00000004937
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Sg; Sgt; Stg; AI194281; D10Ertd190; D10Ertd190e; 5330427H01Rik
    Expression
    Ubiquitous expression in adrenal adult (RPKM 191.2), mammary gland adult (RPKM 106.5) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Sgta in Genome Data Viewer
    Location:
    10 C1; 10 39.72 cM
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (80879905..80896105, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (81044071..81060271, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 10 NC_000076.5 (80506818..80522899, complement)

    Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene DIRAS family, GTP-binding RAS-like 1 Neighboring gene predicted gene 16099 Neighboring gene solute carrier family 39 (zinc transporter), member 3 Neighboring gene thimet oligopeptidase 1 Neighboring gene cAMP responsive element binding protein 3-like 3

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC6336

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables BAT3 complex binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables molecular adaptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables protein heterodimerization activity ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    enables protein homodimerization activity ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    enables protein self-association ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    part_of TRC complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    small glutamine-rich tetratricopeptide repeat-containing protein alpha
    Names
    alpha-SGT
    small glutamine-rich tetratricopeptide repeat (TPR) containing protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001358549.1NP_001345478.1  small glutamine-rich tetratricopeptide repeat-containing protein alpha isoform 1

      Status: VALIDATED

      Source sequence(s)
      AK051005, AK079168, BY143324, BY287841, CD775676
      Consensus CDS
      CCDS35990.1
      Conserved Domains (3) summary
      sd00006
      Location:92120
      TPR; TPR repeat [structural motif]
      pfam16546
      Location:564
      SGTA_dimer; Homodimerisation domain of SGTA
      cl26005
      Location:106212
      PLN03088; SGT1, suppressor of G2 allele of SKP1; Provisional
    2. NM_001358550.1NP_001345479.1  small glutamine-rich tetratricopeptide repeat-containing protein alpha isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC152500, AK051005, BY084509, CD775676
      Consensus CDS
      CCDS88056.1
      Related
      ENSMUSP00000151949.2, ENSMUST00000218208.2
      Conserved Domains (3) summary
      PLN03088
      Location:105211
      PLN03088; SGT1, suppressor of G2 allele of SKP1; Provisional
      sd00006
      Location:91119
      TPR; TPR repeat [structural motif]
      pfam16546
      Location:564
      SGTA_dimer; Homodimerization domain of SGTA
    3. NM_024499.2NP_078775.1  small glutamine-rich tetratricopeptide repeat-containing protein alpha isoform 1

      See identical proteins and their annotated locations for NP_078775.1

      Status: VALIDATED

      Source sequence(s)
      AC152500, AK051005, AK079168, BY084509, CD775676
      Consensus CDS
      CCDS35990.1
      UniProtKB/Swiss-Prot
      Q8BJU0
      Related
      ENSMUSP00000005067.6, ENSMUST00000005067.6
      Conserved Domains (3) summary
      sd00006
      Location:92120
      TPR; TPR repeat [structural motif]
      pfam16546
      Location:564
      SGTA_dimer; Homodimerisation domain of SGTA
      cl26005
      Location:106212
      PLN03088; SGT1, suppressor of G2 allele of SKP1; Provisional

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000076.7 Reference GRCm39 C57BL/6J

      Range
      80879905..80896105 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006513877.2XP_006513940.1  small glutamine-rich tetratricopeptide repeat-containing protein alpha isoform X1

      See identical proteins and their annotated locations for XP_006513940.1

      UniProtKB/Swiss-Prot
      Q8BJU0
      UniProtKB/TrEMBL
      Q3TN35
      Conserved Domains (3) summary
      PLN03088
      Location:105211
      PLN03088; SGT1, suppressor of G2 allele of SKP1; Provisional
      sd00006
      Location:91119
      TPR; TPR repeat [structural motif]
      pfam16546
      Location:564
      SGTA_dimer; Homodimerization domain of SGTA
    2. XM_030245176.2XP_030101036.1  small glutamine-rich tetratricopeptide repeat-containing protein alpha isoform X2

      Conserved Domains (2) summary
      PLN03088
      Location:4110
      PLN03088; SGT1, suppressor of G2 allele of SKP1; Provisional
      sd00006
      Location:2353
      TPR; TPR repeat [structural motif]
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