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    Nhp2 NHP2 ribonucleoprotein [ Mus musculus (house mouse) ]

    Gene ID: 52530, updated on 12-Aug-2018

    Summary

    Official Symbol
    Nhp2provided by MGI
    Official Full Name
    NHP2 ribonucleoproteinprovided by MGI
    Primary source
    MGI:MGI:1098547
    See related
    Ensembl:ENSMUSG00000001056 Vega:OTTMUSG00000005610
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Nola2; D11Ertd175e; 2410130M07Rik
    Expression
    Ubiquitous expression in placenta adult (RPKM 67.7), liver E14 (RPKM 49.7) and 28 other tissues See more
    Orthologs

    Genomic context

    See Nhp2 in Genome Data Viewer
    Location:
    11 B1.3; 11 31.14 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 11 NC_000077.6 (51619773..51623714)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (51433275..51437216)

    Chromosome 11 - NC_000077.6Genomic Context describing neighboring genes Neighboring gene collagen, type XXIII, alpha 1 Neighboring gene 5-phosphohydroxy-L-lysine phospholyase Neighboring gene heterogeneous nuclear ribonucleoprotein A/B Neighboring gene RIKEN cDNA D930048N14 gene Neighboring gene required for meiotic nuclear division 5 homolog B Neighboring gene predicted gene, 30058 Neighboring gene NEDD4 binding protein 3

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    RNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    box H/ACA snoRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    box H/ACA snoRNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    telomerase RNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    cleavage involved in rRNA processing IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    maturation of LSU-rRNA IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    rRNA processing IEA
    Inferred from Electronic Annotation
    more info
     
    rRNA pseudouridine synthesis IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    ribosome biogenesis IEA
    Inferred from Electronic Annotation
    more info
     
    snRNA pseudouridine synthesis IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    telomere maintenance via telomerase ISO
    Inferred from Sequence Orthology
    more info
     
    translation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    box H/ACA snoRNP complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    box H/ACA snoRNP complex ISO
    Inferred from Sequence Orthology
    more info
     
    box H/ACA telomerase RNP complex ISO
    Inferred from Sequence Orthology
    more info
     
    nucleolus IEA
    Inferred from Electronic Annotation
    more info
     
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    telomerase holoenzyme complex ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    H/ACA ribonucleoprotein complex subunit 2
    Names
    H/ACA small nucleolar RNPs
    NHP2 ribonucleoprotein homolog
    nucleolar protein family A, member 2
    snoRNP protein NHP2

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001364736.1NP_001351665.1  H/ACA ribonucleoprotein complex subunit 2 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AK019134, AV472909, CR518445
      Conserved Domains (1) summary
      cl00600
      Location:4677
      Ribosomal_L7Ae; Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
    2. NM_026631.4NP_080907.1  H/ACA ribonucleoprotein complex subunit 2 isoform 1

      See identical proteins and their annotated locations for NP_080907.1

      Status: VALIDATED

      Source sequence(s)
      AL645602
      Consensus CDS
      CCDS24655.1
      UniProtKB/Swiss-Prot
      Q9CRB2
      Related
      ENSMUSP00000120014.1, OTTMUSP00000005780, ENSMUST00000127405.1
      Conserved Domains (1) summary
      pfam01248
      Location:46137
      Ribosomal_L7Ae; Ribosomal protein L7Ae/L30e/S12e/Gadd45 family

    RNA

    1. NR_157294.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AK019134, BF467095, CR518445

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000077.6 Reference GRCm38.p4 C57BL/6J

      Range
      51619773..51623714
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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