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    Ppp2r2d protein phosphatase 2, regulatory subunit B, delta [ Mus musculus (house mouse) ]

    Gene ID: 52432, updated on 21-Oct-2021

    Summary

    Official Symbol
    Ppp2r2dprovided by MGI
    Official Full Name
    protein phosphatase 2, regulatory subunit B, deltaprovided by MGI
    Primary source
    MGI:MGI:1289252
    See related
    Ensembl:ENSMUSG00000041769
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    MDS026; D7Ertd753e; 1300017E19Rik
    Expression
    Ubiquitous expression in testis adult (RPKM 18.0), whole brain E14.5 (RPKM 10.6) and 28 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Ppp2r2d in Genome Data Viewer
    Location:
    7 F4; 7 82.95 cM
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (138448073..138484786)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (138846350..138883057)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 7 NC_000073.5 (146038069..146074740)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 30874 Neighboring gene mitogen-activated protein kinase 1 interacting protein 1 Neighboring gene BCL2/adenovirus E1B interacting protein 3 Neighboring gene gamma-glutamyl hydrolase pseudogene Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables protein phosphatase regulator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within cell division IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in peptidyl-serine dephosphorylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of protein phosphatase type 2A complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001347618.1NP_001334547.1  serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) contains an alternate exon in the 5' end and uses a downstream start codon compared to variant 1. It encodes isoform 2, which is shorter at the N-terminus compared to isoform 1.
      Source sequence(s)
      AC149221
      Consensus CDS
      CCDS85447.1
      UniProtKB/TrEMBL
      F6RV17
      Conserved Domains (2) summary
      COG5170
      Location:2283
      CDC55; Serine/threonine protein phosphatase 2A, regulatory subunit [Signal transduction mechanisms]
      sd00039
      Location:2157
      7WD40; WD40 repeat [structural motif]
    2. NM_026391.2NP_080667.1  serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform isoform 1

      See identical proteins and their annotated locations for NP_080667.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the longer isoform (1).
      Source sequence(s)
      BC066022
      Consensus CDS
      CCDS21950.1
      UniProtKB/Swiss-Prot
      Q925E7
      Related
      ENSMUSP00000040321.7, ENSMUST00000041097.13
      Conserved Domains (2) summary
      COG5170
      Location:14448
      CDC55; Serine/threonine protein phosphatase 2A, regulatory subunit [Signal transduction mechanisms]
      sd00039
      Location:3785
      7WD40; WD40 repeat [structural motif]

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      138448073..138484786
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006508015.3XP_006508078.1  serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform isoform X1

      See identical proteins and their annotated locations for XP_006508078.1

      UniProtKB/TrEMBL
      F6RV17
      Conserved Domains (2) summary
      COG5170
      Location:2283
      CDC55; Serine/threonine protein phosphatase 2A, regulatory subunit [Signal transduction mechanisms]
      sd00039
      Location:2157
      7WD40; WD40 repeat [structural motif]
    2. XM_036153235.1XP_036009128.1  serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform isoform X1

      Conserved Domains (2) summary
      COG5170
      Location:2283
      CDC55; Serine/threonine protein phosphatase 2A, regulatory subunit [Signal transduction mechanisms]
      sd00039
      Location:2157
      7WD40; WD40 repeat [structural motif]
    3. XM_030242762.2XP_030098622.1  serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform isoform X1

      Conserved Domains (2) summary
      COG5170
      Location:2283
      CDC55; Serine/threonine protein phosphatase 2A, regulatory subunit [Signal transduction mechanisms]
      sd00039
      Location:2157
      7WD40; WD40 repeat [structural motif]
    4. XM_030242764.2XP_030098624.1  serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform isoform X1

      Conserved Domains (2) summary
      COG5170
      Location:2283
      CDC55; Serine/threonine protein phosphatase 2A, regulatory subunit [Signal transduction mechanisms]
      sd00039
      Location:2157
      7WD40; WD40 repeat [structural motif]
    5. XM_017322350.3XP_017177839.1  serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform isoform X1

      UniProtKB/TrEMBL
      F6RV17
      Conserved Domains (2) summary
      COG5170
      Location:2283
      CDC55; Serine/threonine protein phosphatase 2A, regulatory subunit [Signal transduction mechanisms]
      sd00039
      Location:2157
      7WD40; WD40 repeat [structural motif]
    6. XM_030242766.2XP_030098626.1  serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform isoform X1

      Conserved Domains (2) summary
      COG5170
      Location:2283
      CDC55; Serine/threonine protein phosphatase 2A, regulatory subunit [Signal transduction mechanisms]
      sd00039
      Location:2157
      7WD40; WD40 repeat [structural motif]
    7. XM_006508020.5XP_006508083.1  serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform isoform X2

      Conserved Domains (2) summary
      COG5170
      Location:31280
      CDC55; Serine/threonine protein phosphatase 2A, regulatory subunit [Signal transduction mechanisms]
      sd00039
      Location:68119
      7WD40; WD40 repeat [structural motif]
    8. XM_030242763.1XP_030098623.1  serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform isoform X1

      Conserved Domains (2) summary
      COG5170
      Location:2283
      CDC55; Serine/threonine protein phosphatase 2A, regulatory subunit [Signal transduction mechanisms]
      sd00039
      Location:2157
      7WD40; WD40 repeat [structural motif]
    9. XM_036153233.1XP_036009126.1  serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform isoform X1

      Related
      ENSMUSP00000119004.2, ENSMUST00000155672.8
      Conserved Domains (2) summary
      COG5170
      Location:2283
      CDC55; Serine/threonine protein phosphatase 2A, regulatory subunit [Signal transduction mechanisms]
      sd00039
      Location:2157
      7WD40; WD40 repeat [structural motif]
    10. XM_036153234.1XP_036009127.1  serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform isoform X1

      Conserved Domains (2) summary
      COG5170
      Location:2283
      CDC55; Serine/threonine protein phosphatase 2A, regulatory subunit [Signal transduction mechanisms]
      sd00039
      Location:2157
      7WD40; WD40 repeat [structural motif]
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