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    Cdca8 cell division cycle associated 8 [ Mus musculus (house mouse) ]

    Gene ID: 52276, updated on 31-Jan-2019

    Summary

    Official Symbol
    Cdca8provided by MGI
    Official Full Name
    cell division cycle associated 8provided by MGI
    Primary source
    MGI:MGI:1196274
    See related
    Ensembl:ENSMUSG00000028873
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    BOR; DasraB; MESRGP; AU044747; Borealin; D4Ertd421e; 4831429J16Rik
    Expression
    Broad expression in liver E14 (RPKM 40.8), liver E14.5 (RPKM 38.3) and 17 other tissues See more
    Orthologs

    Genomic context

    See Cdca8 in Genome Data Viewer
    Location:
    4 D2.2; 4 57.93 cM
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 4 NC_000070.6 (124918465..124936917, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 4 NC_000070.5 (124595709..124614161, complement)

    Chromosome 4 - NC_000070.6Genomic Context describing neighboring genes Neighboring gene yrdC domain containing (E.coli) Neighboring gene mannosidase, endo-alpha-like Neighboring gene RIKEN cDNA 1700125G02 gene Neighboring gene Eph receptor A10 Neighboring gene RIKEN cDNA 9930104L06 gene Neighboring gene predicted gene, 40243

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    cell division IEA
    Inferred from Electronic Annotation
    more info
     
    chromosome organization ISO
    Inferred from Sequence Orthology
    more info
     
    mitotic metaphase plate congression ISO
    Inferred from Sequence Orthology
    more info
     
    mitotic sister chromatid segregation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    chromocenter IDA
    Inferred from Direct Assay
    more info
    PubMed 
    chromosome IEA
    Inferred from Electronic Annotation
    more info
     
    chromosome passenger complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    chromosome passenger complex ISO
    Inferred from Sequence Orthology
    more info
     
    chromosome, centromeric region IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    chromosome, centromeric region ISO
    Inferred from Sequence Orthology
    more info
     
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    intercellular bridge ISO
    Inferred from Sequence Orthology
    more info
     
    midbody ISO
    Inferred from Sequence Orthology
    more info
     
    nucleolus ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    protein-containing complex ISO
    Inferred from Sequence Orthology
    more info
     
    spindle midzone IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    borealin
    Names
    MESrg
    cell division cycle-associated protein 8
    embryonic stem cell-related

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_026560.4NP_080836.3  borealin

      See identical proteins and their annotated locations for NP_080836.3

      Status: VALIDATED

      Source sequence(s)
      AK077717, BY137168
      Consensus CDS
      CCDS18631.1
      UniProtKB/Swiss-Prot
      Q8BHX3
      Related
      ENSMUSP00000081319.3, ENSMUST00000084296.9
      Conserved Domains (2) summary
      pfam10444
      Location:2276
      Nbl1_Borealin_N; Nbl1 / Borealin N terminal
      pfam10512
      Location:170284
      Borealin; Cell division cycle-associated protein 8

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000070.6 Reference GRCm38.p4 C57BL/6J

      Range
      124918465..124936917 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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