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    Cdca8 cell division cycle associated 8 [ Mus musculus (house mouse) ]

    Gene ID: 52276, updated on 23-Jun-2021

    Summary

    Official Symbol
    Cdca8provided by MGI
    Official Full Name
    cell division cycle associated 8provided by MGI
    Primary source
    MGI:MGI:1196274
    See related
    Ensembl:ENSMUSG00000028873
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Bo; Da; BOR; DasraB; MESRGP; AU044747; Borealin; D4Ertd421; D4Ertd421e; 4831429J16Rik
    Expression
    Broad expression in liver E14 (RPKM 40.8), liver E14.5 (RPKM 38.3) and 17 other tissues See more
    Orthologs
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    Genomic context

    See Cdca8 in Genome Data Viewer
    Location:
    4 D2.2; 4 57.93 cM
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (124812258..124830710, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (124918465..124936917, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 4 NC_000070.5 (124595709..124614161, complement)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene yrdC domain containing (E.coli) Neighboring gene mannosidase, endo-alpha-like Neighboring gene RIKEN cDNA 1700125G02 gene Neighboring gene Eph receptor A10 Neighboring gene RIKEN cDNA 9930104L06 gene Neighboring gene predicted gene 12930 Neighboring gene predicted gene, 32371

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within cell division IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in chromosome organization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in mitotic metaphase plate congression ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in mitotic sister chromatid segregation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in chromocenter IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in chromosome IEA
    Inferred from Electronic Annotation
    more info
     
    part_of chromosome passenger complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of chromosome passenger complex ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in chromosome, centromeric region IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in chromosome, centromeric region ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    located_in intercellular bridge ISO
    Inferred from Sequence Orthology
    more info
     
    located_in midbody ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    part_of protein-containing complex ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in spindle midzone IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    borealin
    Names
    MESrg
    cell division cycle-associated protein 8
    embryonic stem cell-related

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_026560.4NP_080836.3  borealin

      See identical proteins and their annotated locations for NP_080836.3

      Status: VALIDATED

      Source sequence(s)
      AK077717, BY137168
      Consensus CDS
      CCDS18631.1
      UniProtKB/Swiss-Prot
      Q8BHX3
      Related
      ENSMUSP00000081319.4, ENSMUST00000084296.10
      Conserved Domains (2) summary
      pfam10444
      Location:2276
      Nbl1_Borealin_N; Nbl1 / Borealin N terminal
      pfam10512
      Location:170284
      Borealin; Cell division cycle-associated protein 8

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      124812258..124830710 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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