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    Agpat5 1-acylglycerol-3-phosphate O-acyltransferase 5 (lysophosphatidic acid acyltransferase, epsilon) [ Mus musculus (house mouse) ]

    Gene ID: 52123, updated on 23-Jun-2021

    Summary

    Official Symbol
    Agpat5provided by MGI
    Official Full Name
    1-acylglycerol-3-phosphate O-acyltransferase 5 (lysophosphatidic acid acyltransferase, epsilon)provided by MGI
    Primary source
    MGI:MGI:1196345
    See related
    Ensembl:ENSMUSG00000031467
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    D8Ertd319; D8Ertd319e; 1110013A05Rik
    Expression
    Ubiquitous expression in ovary adult (RPKM 12.3), placenta adult (RPKM 11.5) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Agpat5 in Genome Data Viewer
    Location:
    8 A1.3; 8 10.3 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (18896295..18934429)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (18846279..18884413)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 8 NC_000074.5 (18846279..18884413)

    Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene microcephaly, primary autosomal recessive 1 Neighboring gene angiopoietin 2 Neighboring gene predicted gene, 53403 Neighboring gene predicted gene, 35934 Neighboring gene X-linked Kx blood group related 5 Neighboring gene predicted gene, 40464

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 
    • Endonuclease-mediated (1) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables 1-acylglycerol-3-phosphate O-acyltransferase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables 1-acylglycerol-3-phosphate O-acyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables acyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in endomembrane system IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
     
    located_in endoplasmic reticulum membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in mitochondrion HDA PubMed 
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nuclear envelope ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon
    Names
    1-AGP acyltransferase 5
    1-AGPAT 5
    LPAAT-epsilon
    lysophosphatidic acid acyltransferase epsilon
    NP_081068.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_026792.3NP_081068.1  1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon

      See identical proteins and their annotated locations for NP_081068.1

      Status: VALIDATED

      Source sequence(s)
      AC129567, BC062903
      Consensus CDS
      CCDS22126.1
      UniProtKB/Swiss-Prot
      Q9D1E8
      Related
      ENSMUSP00000117025.2, ENSMUST00000149565.8
      Conserved Domains (2) summary
      cd07990
      Location:63264
      LPLAT_LCLAT1-like; Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LCLAT1-like
      pfam16076
      Location:260319
      Acyltransf_C; Acyltransferase C-terminus

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000074.7 Reference GRCm39 C57BL/6J

      Range
      18896295..18934429
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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